inclusion

Heinz bodies are most commonly oval or

round.

A mature erythrocyte containing siderotic granules is referred to as a

siderocyte,

Howell-Jolly bodies can be observed on a Wright-stained peripheral blood smear post

splenectomy or when spleen is not working properly

Heinz bodies do not appear on a peripheral blood smear stained with a Wright or Wright-Giemsa-stain. A

supravital stain, such as brilliant green, crystal violet, or new methylene blue is necessary for Heinz bodies to be observed.

The presence of erythrocyte inclusions may indicate the presence of disease.

true

Cabot rings appear as thin, red-

violet-staining strands in the shape of rings, figure eights,

reticulocyte

ribosome

siderotic granules form

ring around the nucleus

If present, how many Howell-Jolly bodies are usually seen within a given erythrocyte?

1

What is the composition of the granules associated with basophilic stippling?

Aggregates of ribosomes

This image represents a field of red blood cells (RBCs) that were stained using a supravital stain. How would these cells appear if they were viewed on a Wright stained smear?

Polychromatophilic RBCs

Heinz bodies are composed of which of the following?

Denatured hemoglobin

Heinz bodies can be found in which of the following disorders?

G6PD deficiency

Siderotic Granules To verify that red cell inclusions contain iron, it is necessary to use an iron stain,

Prussian blue.

In which of the following conditions would you expect to find Howell-Jolly bodies?

Hyposplenism (low functioning spleen)

In which of the following conditions might Cabot rings be observed in erythrocytes on a Wright-stained peripheral blood smear?

oderate iron deficiency anemia and megaloblastic anemia

Which of the following statements characterize a reticulocyte?

Its reticulum is visible with a supravital stain, such as new methylene blue.

Pappenheimer bodies are also seen

peripheral blood following a splenectomy

Which of the following is NOT present in normal bone marrow and would be associated with a disease or disorder?

Ringed sideroblast

In which of the following disorders would you probably observe coarse basophilic stippling on a Wright-stained peripheral blood smear?

Thalassemia and lead poisoning

Howell-Jolly bodies

presence of megaloblastic anemia or abnormal erythropoiesis.hemolytic anemias, thalassemia, and sickle cell anemia.

Howell jolly bodies

These RBC inclusions contain DNA.

hich of the following statements best describes the appearance of Cabot rings

Thin, reddish-violet-staining strands in the shapes of rings, figure eights, or the letter B

polychromatophilic RBCs

blue-gray appearance when compared to the other RBCs in the field.

Reticulocytes appear

blue-gray on the Wright or Wright-Giemsa-stained smear and are referred to as polychromatophilic red cells

Pappenheimer bodies

by an increase in the storage of iron, such as sideroblastic anemia and thalassemia

The basophilic stippling that is clinically significant is referred to as

coarse stippling

Heinz bodies are commonly associated with

glucose-6-phosphate dehydrogenase (G6PD) deficiency and other red cell enzyme disorders.

Pappenheimer bodies, while visible on a Wright's stained smear, should be confirmed with

iron stain, such as Prussian blue stain.

2 or more can be seen on the holly

jolly bodies

Cabot rings have been observed in

megaloblastic anemia, lead poisoning, severe anemia, leukemia, myelodysplastic syndromes, and other cases of dyserythropoiesis.