Lab XII

Your subject has an arterial O2 content of 18.0 vols%, a venous O2 of 7.6 vols%, an RR interval of 0.43 sec, and a stroke volume of 99 ml/beat. What is this subject's absolute VO2? calculate to 2 decimal places, no units required

1.44 Venous O2 = arterial O2 - avo2 diff avo2 = arterial - venous avo2 diff = Vo2/Q * 100 Q = RR interval/60 = HR HR * SV / 1000 avo2/100 Q * ans

Your subject has an a-vO2difference of 11.7 vols%, an RR interval of 0.36 sec, and an end diastolic volume of 160.3 ml and an end systolic volume of 65 ml. What is this subject's absolute VO2? calculate to 2 decimal places, no units required

1.86 1. avo2 diff = (VO2/Q) * 100 (but it is given) 2. Q = HR * SV/1000 HR = 60/ RR interval SV = EDV - ESV 3. avO2 diff = (VO2/Q) 1. 11.7 vols% 2. 60/0.36 = 166.7 160.3-65 = 95.3 166.7*95.3 = 15886.5/1000 3. 11.7 = VO2/15.89 divide each side by 100 0.117 = VO2/15.89 multiple each side by 15.89 0.117*15.89 = 1.86

Your subject has a cardiac output of 12.5, a heart rate of 112, and a blood pressure of 170/97. What is their stroke volume in ml/beat? (no units required)

111.61 Cardiac output x 1000/heart rate (12.5)(1000/112)

Your subject has a hemoglobin concentration of 14.4, an SaO2 of 97 VO2 of 1.1 cardiac output of 13.4, a heart rate of 158, an end ejection fraction of 62 and a blood pressure of 176/82. What is their end systolic volume in ml? (must include units of ml)

13.4/158 = 0.08481 0.08481*1000 = 84.81 84.81/.62= 136.79 136.79-84.81 = 52

Your subject has an a-vO2difference of 11.8 vols%, an RR interval of 0.38 sec, and an end diastolic volume of 176.8 ml and an end systolic volume of 42 ml. What is this subject's stroke volume in ml? calculate to 2 decimal places, no units required

134.8 SV = EDV - ESV

Your subject has a stroke volume of 124 ml/beat, a heart rate of 114, and a blood pressure of 151/73. What is their cardiac output in L/min? (no units required)

14.1

Your subject has a hemoglobin concentration of 15.4 g/dL, an SaO2 of 97%, a VO2 of 2.2 cardiac output of 14.7, a heart rate of 114, and a blood pressure of 174/99. What is theira-vO2difference? (no units required)

15 (VO2/Q) x 100 (2.2/14.7) (100)

What is a typical resting venous O2 content of an adult male human with average hemoglobin concentrations, arterial O2 saturation, and average resting a-vO2 difference (e.g. [Hb] of 15 g/dL, SaO2 of 98%)? No units required

15.4

What is a typical maximal exercise stroke volume in a trained subject? (use ml)

150

What is a typical resting TPR (in dyn/s.cm5) for an adult human with an average cardiac output and average blood pressure?

1500

Your subject has a hemoglobin concentration of 15.1, an SaO2 of 96 VO2 of 1.3 cardiac output of 13.5, a heart rate of 136, an end ejection fraction of 65 and a blood pressure of 150/94. What is their end diastolic volume in ml? (must include units of ml)

153 Q/HR = SV SV*1000 = SV EF (as a fraction) = SV / EDV >>> to isolate EDV, do SV / EF (as fraction)

What is a typical maximal exercise SBP for an adult female subject?

155

What is a typical maximal exercise SBP for an adult male subject?

164-200

What is a typical maximal exercise a-vO2difference in a trained subject?

17

Your subject has a stroke volume of 101 ml/beat, an RR innterval of 0.352, and a blood pressure of 145/77. What is their cardiac output in L/min? (no units required)

17.2 Q = SV * HR SV needs to be in L/min (divide by 1000) HR = 60/RR

Your subject has a hemoglobin concentration of 14.8, an SaO2 of 96 VO2 of 1.9 cardiac output of 14.7, a heart rate of 155, and a blood pressure of 161/74. What is their arterial O2 content? (must include units )

19.8 Hb * 1.39 * O2 sat%

Your subject has an arterial O2 content of 17.9 vols%, a venous O2 of 6.7 vols%, an RR interval of 0.35 sec, and a stroke volume of 107 ml/beat. What is this subject's absolute VO2? calculate to 2 decimal places, no units required

2.05 1. avO2 diff = (VO2/Q)*100 venous O2 = arterial O2 - avO2 diff 2. Q = HR*SV 3. avO2 diff = (VO2/Q)

What is a typical resting arterial O2 content of an adult male human with average hemoglobin concentrations and arterial O2 saturation ([Hb] of 15 g/dL and an SaO2 of 98%)? No units required

20.4

Your subject has a hemoglobin concentration of 15.3, an SaO2 of 97 VO2 of 2.0 cardiac output of 13.8, a heart rate of 124, and a blood pressure of 176/95. What is their arterial O2 content? (must include units )

20.63 Arterial oxygen content = Hb * 1.39 * O2 sat%

Your subject has a stroke volume of 129 ml/beat, an RR innterval of 0.364, and a blood pressure of 140/81. What is their cardiac output in L/min? (no units required)

21.3 Q = SV * HR - SV needs to be in L/min HR = 60/RR interval 60/0.364 164.84*129 / 1000

What is a typical resting a-vO2difference in an untrained subject?

5

What is a typical resting venous return (in L/min) in an untrained subject?

5

Your subject has a hemoglobin concentration of 13.9 g/dL, an SaO2 of 99%, a VO2 of 1.5 cardiac output of 14.7, a heart rate of 141, and a blood pressure of 171/65. What is their total peripheral resistance? (no units required)

546 TPR = (MAP/Q)*80

Your subject has a hemoglobin concentration of 14.3, an SaO2 of 97 VO2 of 1.8 cardiac output of 14.0, a heart rate of 145, an end ejection fraction of 60 and a blood pressure of 163/76. What is their end systolic volume in ml? (must include units of ml)

64.1

What is a typical resting stroke volume in an untrained subject? (use ml)

75

Your subject has a hemoglobin concentration of 15.4 g/dL, an SaO2 of 97%, a VO2 of 1.3 cardiac output of 13.3, a heart rate of 158, and a blood pressure of 157/70. What is theira-vO2difference? (no units required)

9.8 a-vO2diff = (VO2/Q) * 100

Your subject has a cardiac output of 13.2, a heart rate of 165, and a blood pressure of 135/72. What is their mean arterial pressure? (no units required)

93 MAP = DBP + 1/3 (PP)

Match the following with the appropriate parts of this figure:

A - percent saturation in arterial blood B - 75% G - 100 F - PO2 in systemic tissues I - position of curve with low temperature H - position of curve with high temperature

As stroke volume increases, it would be expected that End Systolic Volume would:

Decrease

Your subject has an a-vO2difference of 8.2 vols%, an RR interval of 0.44 sec, and an end diastolic volume of 176.4 ml and an end systolic volume of 42 ml. What is this cardiac output (use L)? calculate to 2 decimal places, no units required

Q = HR*SV 60/0.44 = 136.36 SV = EDV-ESV 176.4-42 = 134.4 136.36*134.4 = 18326.78/1000 = 18.33

If graph i depicts the changes in a-vO2 difference (y axis) between rest and maximal intensity cycling exercise, what would be appropriate values for a and b on the Y axis in an utrained healthy adult male?

a = 4.5 b = 15.8

If graph i depicts the changes in cardiac output (y axis) between rest and maximal intensity cycling exercise in a healthy untrained subject, what would be appropriate values for points a and b on the y axis in an elite male endurance athlete?

a = 5 b = 42.1

If graph i depicts the changes in a-vO2 difference (y axis) between rest and maximal intensity cycling exercise, what would be appropriate values for a and b on the Y axis in a highly trained healthy adult male?

a = 5.2 b = 17.9

If graph v depicts the changes in venous O2 content (y axis) between rest and maximal intensity cycling exercise, what would be appropriate values for a and b on the Y axis in an untrained healthy adult male?

a = 5.8 b = 14.9

If graph i depicts the changes in DBP (y axis) between rest and maximal isometric knee extensions, what other cardiovascular response(s) to exercise contribute to this change?

an increase in TPR during thist type of activity

If graph i depicts the changes in a-vO2 difference (y axis) between rest and maximal intensity cycling exercise, what factors could be causing this change?

an increase in body temperature

If graph ii depicts the changes in stroke volume (y axis) between rest and maximal intensity cycling exercise in a healthy untrained subject, what factors could be contributing to this change?

an increase in venous return

If graph i depicts the changes in TPR (y axis) between rest and maximal isometric knee extensions, how would this change influence the blood pressure response to exercise?

it is why DBP increases during this type of activity

If graph v depicts the changes in TPR (y axis) between rest and maximal intensity cycling exercise, how would this figure look different if the subject were performing dynamic knee extensions?

it would increase instead of decrease

If graph v depicts the changes in TPR (y axis) between rest and maximal intensity cycling exercise, how would this figure look different if the subject were performing isometric knee extensions?

it would increase instead of decrease

If graph ii depicts the changes in stroke volume (y axis) between rest and maximal intensity cycling exercise, how would this figure look different if we took these measurements in the same subject after 2 months of cycling 5 days per week?

it would increase more and plateau at a higher intensity

If graph v depicts the changes in TPR (y axis) between rest and maximal intensity cycling exercise, how would this figure look different if the subject were performing arm crank exercise?

it would still decrease, but not as much

If graph ii depicts the changes in stroke volume (y axis) between rest and maximal intensity cycling exercise, how would this figure look different if the subject were performing arm crank exercise?

it would still increase, but not as much

If graph i depicts the changes in a-vO2 difference (y axis) between rest and maximal intensity cycling exercise, what factors could be causing this change?

loss of plasma volume

If graph iii depicts the changes in heart rate (y axis) between rest and maximal intensity cycling exercise, what is causing this change?

none of these answers, the heart rate should never be zero for a living subject

If graph iii depicts the changes in cardiac output (y axis) between rest and maximal intensity cycling exercise in a healthy untrained subject, what would be appropriate values for points a and b on the y axis in a healthy untrained female subject?

none of these answers; cardiac output should never be zero in a healhty living subject

If graph i depicts the changes in a-vO2 difference (y axis) between rest and maximal intensity cycling exercise, what factors could be causing this change?

redistribution of blood flow away from inactive tissues and towards active tissues (especially muscle)

If graph i depicts the changes in heart rate (y axis) between rest and maximal intensity cycling exercise, what is causing this change?

three of these answers

If graph ii depicts the changes in stroke volume (y axis) between rest and maximal intensity cycling exercise in a healthy untrained subject, what factors could be contributing to this change?

two of these answers

If graph iv depicts the changes in cardiac output (y axis) during prolonged cylcling exercise (time on the x axis), what factors explain this lack of change?

two of these answers

If graph v depicts the changes in end systolic volume (y axis) between rest and maximal intensity cycling exercise in a healthy untrained subject, what factors could be contributing to this change?

two of these answers

Match the following with the appropriate parts of this figure:

venous O2 content - E 20 Vols% - D PO2 in systemic arteries - G 40 mmHg - F position of curve at rest - I position of curve during exercise - H

Your subject has a hemoglobin concentration of 15.4, an SaO2 of 99 VO2 of 1.4 cardiac output of 12.6, a heart rate of 158, and a blood pressure of 162/73. What is their venous O2 content? (must include units )

venous O2 content = arterial O2 - a-vO2 diff arterial O2 = Hb * 1.39 * SaO2 a-vO2 = VO2/Q then * 100

One of the following graphs depicts the most common changes in diastolic blood pressure (Y axis) from rest to maximal intensity cycing exercise (on the X axis) in a young healthy subject with an appropriate vasodilatory response to exercise. Which graph best illustrates the trend for this variable?

vi

If graph i depicts the changes in a-vO2 difference (y axis) between rest and maximal intensity cycling exercise, what factors could be causing this change?

a decrease in active muscle pO2

If graph vi depicts the changes in DBP (y axis) between rest and maximal cycing exercise, what other cardiovascular response(s) to exercise contribute to this change?

a decrease in TPR during this type of activity

If graph i depicts the changes in a-vO2 difference (y axis) between rest and maximal intensity cycling exercise, what factors could be causing this change?

a decrease in blood pH

which of the following would NOT be expected to increase a-vO2 difference during an exercise bout?

a decrease in pulmonary capillary pO2

Your subject has a hemoglobin concentration of 13.9 g/dL, an SaO2 of 99%, a VO2 of 1.6 cardiac output of 12.1, a heart rate of 139, and a blood pressure of 179/72. What is their total peripheral resistance? (no units required)

711.9 TPR = (MAP/Q)*80

If graph ii depicts the changes in stroke volume (y axis) between rest and maximal intensity cycling exercise in a healthy untrained subject, what would be appropriate values for points a and b on the y axis in a healthy untrained female subject?

a = 65 b = 119

If graph ii depicts the changes in stroke volume (y axis) between rest and maximal intensity cycling exercise in a healthy untrained subject, what would be appropriate values for points a and b on the y axis in an elite male endurance athlete?

a = 72 b = 220

If graph ii depicts the changes in stroke volume (y axis) between rest and maximal intensity cycling exercise in a healthy untrained subject, what factors could be contributing to why this variable plateaus in most subjects during acute exercise?

ventricular filling time decreases at high intensities