Module 9 Patho Cancer

Which of the following statements about alcohol intake and cancer risk is true?

Alcohol intake increases the development of smoking-related cancers

Which of the following is not a typical characteristic of cancer cells?

Decreased responsiveness to growth signals

Which of the following mutational routes is necessary to cause cancer with a tumor suppressor gene mutation?

Deletion of both copies of a tumor suppressor gene

Which of the following cancers always arises from an initial mutation in the blood-forming cells of the bone marrow?

Leukemia

Chronic active hepatitis B infection is a risk factor for developing which of the following types of cancer?

Liver

Radon exposure increases an individual's risk for which of the following cancers?

Lung

Malignant tumors have a tendency to?

all of the above grow rapidly, metastasize to distant tissues, invade surrounding tissues

Which of the following genetic events is capable of activating oncogenes?

amplification

The process of triggering new blood vessel formation in a tumor is called

angiogenesis

Normally, the tumor suppressor gene p53 induces

apoptosis

Mechanisms that cause cancer pain include all of the following expect

cancer cells residing in lymph nodes

Sarcomas are cancers that arise from?

connective tissues

Cervical carcinoma in situ

contains cancer cells that have not invaded the surrounding tissue

Helicobacter pylori infection is a bacterial cause of?

gastric cancer

Cancer-causing mutations to protooncogenes result in?

increased cell division

One way that a tumor suppressor gene can become inactivated in the absence of mutation or deletion is through gene

silencing

Determining the size of the tumor, the degree of node involvement, and the extent of distant metastasis is called

staging

Immortality in cancer cells is obtained through the production of?

telomerase