NSU Genetics Chapter 18 Quiz

Growth of new blood vessels in and around a tumor is called _______________. A. dedifferentiation B. angiogenesis C. invasiveness D. metastasis

B. angiogenesis

Which type of mutation does not cause cancer & can occur in cancerous & noncancerous cells? A. driver mutation B. passenger mutation C. somatic mutation D. germline mutation E. proto-oncogene mutation

B. passenger mutation

Traditional treatments for cancer, such as chemotherapy and radiation, are effective because ___________________. A. they stimulate cells to differentiate B. they kill rapidly dividing cells C. they prevent apoptosis D. they inhibit angiogenesis

B. they kill rapidly dividing cells

Genes that normally promote cell division when it is appropriate are called _________________. A. oncogenes B. tumor suppressor genes C. proto-oncogenes D. DNA repair genes

C. proto-oncogenes

Which of the following statement(s) about cancer are true? A. all tumors are cancerous B. tumor suppressor genes cause cancer when they are activated C. cancer develops when a cell divides less frequently than it should D. cancer can result from inappropriately activated telomerase enzyme E. all of the above

D. cancer can result from inappropriately activated telomerase enzyme

Sporadic cancers result from _________________. A. exposure to a cancer-causing virus B. recessive or dominant germline mutations C. mutation in a sperm or oocyte D. recessive or dominant mutation in a somatic cell

D. recessive or dominant mutation in a somatic cell

Which of the following events at the cellular level can result in the development of cancer? A. increased proportion of stem cells within a tissue B. dedifferentiation C. activation of cancer stem cells D. defective tissue repair E. all of the above

E. all of the above

Mathew has the inherited form of the eye cancer retinoblastoma (RB). His disease is caused by _____________________.

a germline mutation in one RB allele & a somatic mutation on the other allele

The cause of P53-related cancers is __________________.

failure to repair damaged DNA, allowing the cell to continue dividing

Sally was just diagnosed with an aggressive form of breast cancer called HER2. The cancer started because ______________________.

her affected breast cells have extra HER2 receptors for epidermal growth factor, so they receive too many signals to divide