Nursing Application: Antifungals
1. Nystatin 2. Fluconazole 3. Griseofulvin 4. Amphotericin B a. Monitoring Criteria b. Look/Sound Alike Drugs
1a. No routine tests recommended 1b. Dilantin, naftifine, niacin, nitrogylcerin, phenytoin 2a. Creatinine at baseline, Liver Function Tests (LFTs) 2b.Flucytosine, fluoxetine, furosemide, itraconazole, metronidazole 3a. No routine tests recommended 3b. Gastrografin 4a. BUN, Creatinine at baseline, then frequently; CBC; electrolytes; Liver Function Tests 4b. Amphotericin B liposomal confused with: amphotericin B deoxycholate; amphotericin B; amphotericin B lipid complex
The nurse is reviewing instructions for vaginal antifungal drugs with a patient. Which statement by the nurse is an appropriate instruction regarding these drugs?
"Abstain from sexual intercourse until the treatment has been completed and the infection has resolved."
A patient is taking nystatin (Mycostatin) oral lozenges to treat an oral candidiasis infection resulting from inhaled corticosteroid therapy for asthma. Which instruction by the nurse is appropriate?
"Let the lozenge dissolve slowly and completely in your mouth without chewing it."
Why is Charles susceptible to lung infections? Select all that apply.
*He has a chronic condition which weakens the immune system *His age creates a weaker immune system *He has COPD which makes him more susceptible to lung infections
Which of the following are main teaching points to focus on for children like four-year-old Jessica? Select all that apply.
*Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. *Griseofulvin could make you sunburn more easily. Avoid sunlight. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. *Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). *Take with a fatty meal to aid absorption and lessen stomach upset. *Store at room temperature away from moisture, heat, and light. *If you use this medicine long-term, you may need frequent medical tests.
Of the medications listed below, which two can be used to treat oral candidiasis?
*fluconazole *nystatin
1. Fever 2. Hyperactive response 3. Nausea and vomiting 4. Allergic type reactions, but not anaphylaxis
1. Antipyretics 2. Corticosteroids 3. Antiemetics 4. Antihistamines
Griseofulvin is a/an 1.______________ medication used to treat 2._________________ fungal infections.
1. oral 2. systemic
A patient is taking nystatin (Mycostatin) in an oral troche form for oral candidiasis. Which instruction is correct?
Allow the troche to dissolve slowly in the mouth.
Fifteen minutes after an infusion of amphotericin B was started, the patient begins to complain of fever, chills, muscle pain, and nausea. His heart rate has increased slightly, but his blood pressure is down to 100/68 mm Hg. What is the nurse's priority?
Assess for other symptoms of this expected infusion-related reaction.
The nurse is preparing an infusion of amphotericin B for a patient who has a severe fungal infection. Which intervention is appropriate regarding the potential adverse effects of amphotericin B?
Before beginning the infusion, administering an antipyretic and an antiemetic drug
What organ is infected when someone has a aspergillosis infection?
Lungs
Which medication is used to treat oral candidasis?
Nystatin
During therapy with amphotericin B, the nurse will monitor the patient for known adverse effects that would be reflected by which laboratory result?
Serum potassium level of 2.7 mEq/L
The nurse is administering one of the lipid formulations of amphotericin B. When giving this drug, which concept is important to remember?
The lipid formulations are associated with fewer adverse effects than the older drugs.
What macronutrient is it important to consume when taking griseofulvin?
fat
