Osteoporosis book just the drugs (minus charts, theyre in other quizlet)
Alorithm for osteoporosis: No traumma fracture and Sent for DXA testing T-score: -1.1 to -2.4 at femoral neck or spine with FRAX 10-year probability of hip fracture<3% or mjor Osteoporosis-related fracture<20%
1. Bone healthy lifestyle 2. Dietary Calcium 1000-2000 mg/d 3. Vit D 800-1000 UI/d 4. Medication therapy prevention doses (only biphosphonates have these) Re-evaluate q 2 or more years
Alorithm for osteoporosis: No traumma fracture and Sent for DXA testing T-score</= -2.5 at femoral neck or spine OR Tscore -1.1 to -2.4 at femoral neck or spine with FRAX 10-year probability of hip fracture<3% or mjor Osteoporosis-related fracture<20%
1. Bone healthy lifestyle 2. Dietary Calcium 1000-2000 mg/d 3. Vit D 800-1000 UI/d 4. Medication therapy(1stline: alen,rise,zolen, or denos, alt: iban, raloxif, or teripa, Last: Intranasal calc)
Alorithm for osteoporosis: No traumma fracture and Sent for DXA testing Tscore: >/= - 1
1. Bone healthy lifestyle 2. Dietary Calcium 1000-2000 mg/d 3. Vit D 800-1000 UI/d Re-evaluate BMD in 5 yr or as appropriate
Alorithm for osteoporosis: Presence of trauma fracture
1. Evaluate for 2ndary causes 2. Bone healthy lifestyle 3. Dietary Calcium 1000-2000 mg/d 4. Vit D 800-1000 UI/d 5. Medication therapy
Alorithm for osteoporosis: Medication therapy for trauma fracture
1st line: alendronate, risedronate, Zoledronic acid, or denosumab Alt: Ibandronate, Raloxifene, or teriparatide Lastline: Intranasal Calcitronin
Alorithm for osteoporosis: No presence of trauma fracture
They have to be: Woman=/> 65 Man =/>70 Postmenopausal<65 or man 50-69 w/risk of fracture Abnormal BMD test FRAX- major osteoporotic risk>9.3% Radiographic evidence of low bone mass Medical conditions known to increase the risk for bone loss and fracture If they are any of this, procede to DXA testing
So when do we use 1st line: alendronate, risedronate, Zoledronic acid, or denosumab Alt: Ibandronate, Raloxifene, or teriparatide Lastline: Intranasal Calcitronin
Trauma fracture Tscore: -1.1 to -2.5, failed prevention doses Tscore: <-2.5, or -1.1--2.4 w/Fem neck or spne FRAX 10-yr probability >3% or major eosterporosis >20%
What are prevention doses
Used for tscore -1.1 to -2.4 (biphosphonates)