OSU Chapters 2-8
A pharmacist receives an order to compound dexamethasone ophthalmic solution. The compounding monograph lists the following ingredients: Dexamethasone sodium phosphate 1% (E value = 0.17) Sodium chloride QS to make an isotonic solution Sterile water QS AD 10 mL How many milligrams of sodium chloride are needed to make the ophthalmic solution isotonic?
20 (p.142)
The pharmacist receives an order for a female patient (5'2", 189 pounds) to receive a 400 mg/kg infusion of Gammagard based on ideal body weight. Calculate the patient's Gammagard dose in grams.
20 (p.167)
Which of TP's treatments, when given intravenously, will require a non-PVC container? A. Lactated ringers B. Total parenteral nutrition C. Prograf D. Cellcept E. Cubicin
A. Lactated ringers (p.101)
Which of LY's medications treat her angina by decreasing myocardial oxygen demand? (Select ALL that apply.) A. Nitroglycerin B. Furosemide C. Digoxin D. Coreg CR E. Benicar
A. Nitroglycerin C. Digoxin (p.477)
Which medication on LD's profile can cause peripheral edema? A. Norvasc B. Hydrochlorothiazide C. Aricept D. Glyburide E. Zoloft
A. Norvasc (p.464)
Which of the following provides the least accurate measure of liquids for compounding? A. Pipette B. Oral syringe C. Graduated cylinder D. Mohr pipette E. Glass beaker
A. Pipette (p.250)
Home Medications: Amiodarone 400 mg QD Labs: K = 3.2 (3.5-5) Glucose = 141 (100-125) Ca = 8.4 (8.5-10.5) TSH = 6.5 (0.4-4) Hgb = 12.2 (13.8-17.2) DL's antiarrhythmic treatment could be contributing to which laboratory abnormality? A. Potassium B. Calcium C. TSH D. Hemoglobin E. Glucose
A. Potassium (p.73)
A few months later, CL comes to the HIV clinic complaining of muscle aches and pain in her legs. Which of the following medications could be responsible? A. Zithromax B. Risperdal C. Descovy D. Adderall E. Isentress
B. Risperdal (p.430)
Which of the following drugs exerts its antiarrhythmic effect by blocking potassium channels in the myocardium, leading to prolongation of the refractory period? A. Lidocaine B. Sotalol C. Flecainide D. Verapamil E. Adenosine
B. Sotalol (p.513)
What value is needed to determine the volume of peanut oil (in milliliters) required to prepare the cooling ointment? A. pH B. Specific gravity C. Valence D. E value E. Molecular weight
B. Specific gravity (p.135)
Which of the following is an independent variable in this study? A. Type of ACS presentation B. LDL levels C. Ezetimibe/simvastatin treatment D.All-cause mortality E. Stroke
C. Ezetimibe/simvastatin treatment (p.203)
Home medication: Nasacort Allergy 24 HR When FW is picking up his medication refills at the pharmacy, he tells the pharmacist that he cannot find his over-the-counter allergy medication on the usual shelf. The pharmacist confirms that his particular brand is out of stock, but tells FW that he can purchase another brand, or a generic, with the same active ingredient. What ingredient should FW be looking for in the products available? A. Budesonide B.Mometasone C.Fluticasone D. Triamcinolone E. Ciclesonide
C. Fluticasone (p.558)
The pharmacy department received the following parenteral nutrition orders for a 79-year-old patient. Nutrition Goal: 1750 total calories per day from all sources 2-in-1 Parenteral Solution: Dextrose 312 grams Amino acids 62 grams Sodium chloride 32 mEg Sodium acetate 12 mEg Potassium 20 mEg Magnesium sulfate 10 mEq Phosphate 28 mmol Calcium 24.5 mEg Multivitamins 10 ml Trace elements 1 ml Famotidine 10 mg Regular insulin 10 units Sterile water qs ad 1900 mL The patient's condition has improved and the pharmacy receives the following order: "Convert patient from 2-in-1 PN + lipids to continuous NG tube feeding with Glucerna Glycemic Control (1.2 kcal/mL). Start at 50% of current calories and infuse over 24 hours. At what rate (mL/hr) should the Glucerna Glycemic Control be set to infuse? (Answer
10 (p.148)
The pharmacy department received the following parenteral nutrition orders for a 79-year-old patient. Nutrition Goal: 1750 total calories per day from all sources 30% Intralipid Infuse over 12 hours daily At what rate (mL/hr) should the 30% Intralipid be infused?
10 (p.148)
New order: Cubicin 6 mg/kg IV daily Discontinue IV fluids Start TPN: 1800 mL D20W, 750 mL FreAmine 8.5%, 252 mL Intralipid 20%, 50 mL of electrolytes/minerals The pharmacy has D70W and D10W in stock. How many milliliters of D70W are needed to prepare the TPN ordered?
100 (p.137)
A 48-year-old male patient (5'11", 78 kg, SCr = 1.1 mg/dL) is on digoxin 0.25 mg PO daily for rate control of atrial fibrillation. He is rushed to the ICU after a multi-vehicle trauma on the highway. His digoxin dose will need to be converted to intravenous (IV) form. The pharmacist looks up the conversion and notes that the dose should be reduced 20% when converting from oral to IV. How many micrograms of IV digoxin should the patient receive per day?
200 (p.119)
A patient is receiving gentamicin 180 mg IV Q8H for a Gram-negative infection. A peak and trough are ordered and the pharmacist on the pharmacokinetic dosing service determines the following patient-specific information: Vd = 31.5 L CI = 6.3 L/hr What is the half-life (hrs) of gentamicin in this patient?
3.2 (p.1017)
While checking drips in the intensive care unit, the pharmacist notes that one of the patients (weight = 62 kg) is receiving 250 mL D5W to infuse at 3 mcg/kg/minute. There are currently 100 a cisatracurium drip. The current order is for cisatracurium 100 mg in milliliters remaining in the bag. Assuming no rate changes, how many hours does the pharmacist have before the bag will be empty and the nurse will need to hang a new bag?
3.6 (p.169)
While checking drips in the intensive care unit, the pharmacist notes that one of the patients (weight = 62 kg) is receiving a cisatracurium drip. The current order is for cisatracurium 100 mg in 250 mL D5W to infuse at 3 mcg/kg/minute. There are currently 100 milliliters remaining in the bag. Assuming no rate changes, how many hours does the pharmacist have before the bag will be empty and the nurse will need to hang a new bag?
3.6 (p.169)
Labs: (4/8) aPTT: 127 sec On the morning on April 8th, SZ's heparin drip is running at 16.5 mL/hr. The hospital uses premixed heparin bags (25,000 units/250 mL). What rate (mL/hr) should the infusion be changed to? Heparin dose adjustment protocol: aPTT: 119-135 Rebolus or Hold: NONE Rate Adjustment: Decrease by 2 units/kg/hr Recheck PTT: 6 hrs
30 (p.169)
A total of 18,144 patients were included; 9,067 patients recirves ezetimibe/simvastatin and 9,077 patients receives simvastatin alone. A safety analysis in this study showed that 181 patients in the simvastatin group experienced myopathy compared to 422 patients in the ezetimibe/simvastatin group. What isthe number needed to harm for this endpoint?
33 (p.210)
Mg (mEq/L) = 1.1 (1.3-2.1) How many milliequivalents of magnesium is DL receiving daily to correct his serum magnesium level (M.W. MgO = 40.3)?
40 (p.146)
The pharmacy department received the following parenteral nutrition orders for a 79-year-old patient. Nutrition Goal: 1750 total calories per day from all sources 2-in-1 Parenteral Solution: Dextrose 312 grams Amino acids 62 grams Sodium chloride 32 mEq Sodium acetate 12 mEq Potassium 20 mEg Magnesium sulfate 10 mEq Phosphate 28 mmol Calcium 24.5 mEg Multivitamins 10 mL Trace elements 1 mL Famotidine 10 mg Regular insulin 10 units Sterile water qs ad 1900 mL The pharmacy technician compounding the PN solution used potassium phosphate to add the 28 mmol of phosphate needed. If potassium phosphate solution contains 3 mmol of phosphate and 4.4 mEq of potassium in each mL, how many extra mEq of potassium have been added beyond what was prescribed?
41 (p.158)
The pharmacy department received the following parenteral nutrition orders for a 79-year-old patient. Nutrition Goal: 1750 total calories per day from all sources 2-in-1 Parenteral Solution: Dextrose 312 grams Amino acids 62 grams Sodium chloride 32 mEq Sodium acetate 12 mEg Potassium 20 mEq Magnesium sulfate 10 mEq Phosphate 28 mmol Calcium 24.5 mEg Multivitamins 10 mL Trace elements 1 mL Famotidine 10 mg Regular insulin 10 units Sterile water qs ad 1900 mL 30% Intralipid: Infuse over 12 hours daily If phosphate contains 2 mEq PO4/mmol, what is the combined calcium and phosphorus in this parenteral nutrition order in mEg/L?
42.4 (p.159)
The hazard rate for the primary endpoint (CV death, MI, UA, coronary revascularization beyond 30 days, or stroke) was lower in the ezetimibe/simvastatin group compared with the simvastatin alone group (32.7% vs. 34.7%, 95% CI 0.89-0.99). What is the relative risk reduction of the primary endpoint in the intent-to-treat population?
5.8 (p.208)
A patient will receive a continuous infusion of bivalirudin 250 mg in 500 mL to run at 105 mg/hr. The hospital has IV tubing sets that deliver 15 drops/mL. What should the flow rate be in drops/minute to deliver this infusion?
53 (p.172)
The pharmacist is compounding the ointment below. Cooling Ointment (Water-in-OiI) Ingredients: Peanut oil 57.5 g White wax 12.5 g Glycerol monooleate 5 g Rose oil 1 drop Water 25 g Assuming the rose oil drop has a negligible weight, what is the percentage strength (w/w) of peanut oil in the prepared compound?
57.5 (p.128)
A pharmacist receives an order for a D10W infusion to run at 45 mL/hour. The pharmacy has only D50W and sterile water available, due to a purchasing miscommunication. How much D50W should be added to one liter of sterile water to make D10W?
60 (p.137)
A surgery patient is receiving 1,420 mL of D30W, 460 mL of 10% amino acid solution, 210 mL of 20% Intralipid and 45 mL of calories is represented by dextrose? What percentage of the non-protein calories is represented by dextrose?
67 (p.148)
A prescriber orders 500 ml of a 1:400 acetic acid bladder irrigation for a patient. How many milliliters of a 1.5% stock solution of acetic acid are needed to prepare the bladder irrigation?
83 (p.132)
A pharmacist is preparing a 6% benzoyl peroxide wash from commercially available 8% wash and an inert diluent. How many milliliters of diluent should be added to 65 mL of the 8% wash to prepare the 6% strength?
86.7 (p.136)
A patient who is new to insulin therapy calls the pharmacy for clarification about how to store her ovolog insulin pens. Which of the following is the correct instruction for the patient? A. "In use" pens stored at room temperature are stable for 2 weeks B. Unused and unopened pens stored in the refrigerator are stable for 6 weeks C. Unused and unopened pens stored in the refrigerator are stable until the expiration date on the product D. "In use" pens stored at room temperature are stable for 4 weeks E. "In use" pens stored at room temperature are stable for 8 weeks
A. "In use" pens stored at room temperature are stable for 2 weeks C. Unused and unopened pens stored in the refrigerator are stable until the expiration date on the product (p.659)
A pharmacy technician is preparing a phenytoin drip. What is the preferred diluent and maximum rate of infuslon A. 50 mg/min, NS only B. 50 mg/min, dextrose only C. 150 mg/min, NS only D. 25 mg/min, NS only E. 25 mg/min, dextrose only
A. 50 mg/min, NS only (p.946)
A pharmacist is compounding a chewable (gummy) lozenge for a pediatric patient. Which of the following would be an appropriate ingredient to prepare the lozenge base? A. Acacia B. Syrup C. Sucrose D. Cocoa butter E. Gelatin
A. Acacia (p.276)
JN is a 58-year-old Caucasian male who is following up with his PCP after having routine lab checks. He complains of frequent urination and "head cold" with cough that is currently keeping him awake at night. He takes no home medications. Height: 5'9" weight: 236 pounds BP: 159/92 mmHg, HR: 87 BPM RR: 13 BPM Temp: 98.8°F Glucose (mg/dL) = 302 (100 -125) A1C (%) = 8.6 Which of the following risk reduction strategies should be recommended for JN? (select ALL that apply) A. Annual urine albumin exrerion test B. Assessment for peripheral neuropathy every 3 years C. Waist circumference <40 inches D. Increased intake of omega-3 fatty acids E. Aspirin 325 mg daily
A. Annual urine albumin exrerion test B. Assessment for peripheral neuropathy every 3 years C. Waist circumference <40 inches D. Increased intake of omega-3 fatty acids (p.638)
Which of the following are high-alert medications or classes according to ISMP? (Select ALL that apply.) A. Anticoagulants B. Insulin C. Hypertonic saline D. Opioids E. SSRIS
A. Anticoagulants B. Insulin D. Opioids (p.991)
Plan: Infectious colitis vs. inflammatory bowel disease. Consult Gl and start Cipro and Flagyl. The pharmacist reviews the antibiotic orders for BG. Which of the following safety concerns should the pharmacist discuss with the physician? (Select ALL that apply.) A. Bleeding risk B. Risk for constipation C. Risk for red man syndrome D. Risk for arrhythmia E. CNS side effects
A. Bleeding risk C. Risk for red man syndrome D. Risk for arrhythmia (p.357)
A patient has a soy allergy listed on her medical profile. Which of the following medications should be avoided in this patient? (Select ALL that apply.) A. Dexmedetomidine B. Clevidipine C. Prometrium D. Ativan E. Propofol
A. Dexmedetomidine B. Clevidipine D. Ativan (p.1007)
Which of the following generic substitutions is equivalent to the medication CL uses for ADHD? A. Dextroamphetamine/Amphetamine B. Lisdexamfetamine C. Methylphenidate D. Dexmethylphenidate E. Methamphetamine
A. Dextroamphetamine/Amphetamine (p.907)
SZ is a 77-year-old female patient admitted to the hospital on April 7th for worsening SOB that the patient describes as mucb worse than her "typical heart failure episodes." In addition, she states that she has been experiencing episodesof nausea and blurry or double vision over the past couple of weeks. Labs: (4/7) Digoxin: 2.6 ng/mL Which of the following is true regarding SZ's initial presentation to the hospital? A. Her digoxin level is too high B. Her INR is too low C. Her calcium level is too low D. She is febrile E. She has a high anion gap
A. Her digoxin level is too high (p.499)
Home Medications: CellCept 1,000 mg PO BID Prograf 2 mg PO BID Which of the following represents a mechanism of action of TP's transplant medications? A. Inhibitor of tyrosine kinase B. Inhibitor of T-lymphocyte proliferation C. mTOR kinase inhibitor D. Binds CD80 and CD86 E. Monoclonal antibody
A. Inhibitor of tyrosine kinase (p.781)
JN is a 58-year-old Caucasian male who is following up with his PCP after having routine labs checked. He complains of frequent urination and "head cold" with cough that is currently keeping him awake at night. He takes no home medications. Vaccine History: Influenza annually, Tdap (2 years ago) JN is a candidate for which immunization? A. Prenar 13 B. H. Influenzae type B C. Boostrix D. Bexsero E. Shingrix
A. Prenar 13 (p.329)
A child is staying with his grandmother for the weekend. The grandmother is reading the instructions for the proper use of the child's EpiPen. Which of the following is an incorrect statement? A. Remove pants or expose the upper thigh. B. Keep the injector in the outer thigh while slowly counting for 3 seconds. C. Remove the injector and rub the area where the medication entered the skin for 10 seconds. D. Swing and push the injector into the outer thigh at a 90-degree angle. E. Grasp the injector in one fist with the tip pointing down.
A. Remove pants or expose the upper thigh. (p.1006)
Home medications: Combivent Respimat Which of the following inhalers contain medications in the same drug class as SZ's current COPD treatment? A. Tiotropium (Spriva) B. Indacaterol (Arcapta Neohaler) C. Fluticasone/salmeterol (Advair) D. Glycopyrrolate/formoterol (Bevespi Aerosphere) E. Budesonide/formoterol (Symbicort)
A. Tiotropium (Spriva) (p.621)
LY is a 72-year-old female who is admitted to a skilled nursing facility on June 7. Past Medical History: Heart failure, hypertension, Parkinson disease, depression, angina Medications: Coreg CR 20 mg PO daily Benicar 20 mg PO daily Keflex 500 mg PO BID x 7 days Digoxin 0.125 mg PO daily Entacapone 200 mg PO daily Furosemide 40 mg PO daily Celexa 40 mg PO daily Nitroglycerin 0.4 mg tablet SL PRN The pharmacist conducting medication therapy managment identifies that LY is a possible candidate for: (select ALL that apply) A. Warfarin B. Aspirin C. Amitriptyline D. Diltiazem E. Rosuvastatin
A. Warfarin B. Aspirin E. Rosuvastatin (p.475)
What is the beyond use date of this formulation? A. 14 days B. 6 months C. 3 months D. 30 days E. 1 year
B. 6 months (p.277)
While drawing blood for routine laboratory tests, a phlebotomist accidentally sticks herself with a needle that she has withdrawn from the arm of an HIV-positive patient. What is the appropriate treatment for the phlebotomist? A. A 6-month course of Prezista and Truvada B. A 3-month course of Truvada C. A 4-week course of Truvada D. A 4-week course of Truvada and Isentress E. A 3-month course of Triumeq
B. A 3-month course of Truvada (p.434)
A clinical trial reports the incidence of stroke between a treatment group and a placebo group. The difference in stroke risk is reported along with a p-value of 0.04. Under what conditions would the outcome of stroke be considered statistically significant? A. Alpha = 0.03 B. Alpha = 0.05 C. Alpha = 0.01 D. Beta = 0.1 E. Beta = 0.2
B. Alpha = 0.05 (p.204)
Which of the following are possible side effects from the of an albuterol HFA inhaler? A. Hyperkalemia, throat irritation, bradycardia B. Bradycardia, hyperglycemia, throat irritation C. Tachycardia, hyponatremia, oral candidiasis D. Tremor, oral candidiasis, loose stools E. Palpitations, cough, hyperglycemia
B. Bradycardia, hyperglycemia, throat irritation (p.604)
An investigator is studying a possible link between ingestion of artificial sweeteners and development of breast or prostate cancer. Patients with breast or prostate cancer will be matched with cancer-free controls of the same age and sex, and with similar comorbidities. Study participants will be asked to complete a survey to identify and quantify consumption of artificial sweeteners in the preceding 10 years. What type of study design does this trial represent? A. Case report B. Cohort study C. Case-control study D. Cross-sectional study E. Case series
B. Cohort study (p.217)
A mean corpuscular volume should be monitored for which of BG's medications? A. Dofetilide B. Cyanocobalamin C. Soma D. Cogentin E. Finasteride
B. Cyanocobalamin (p.546)
The hospital has an admission protocol for prevention of venous theomboembolism (VTE) in hospitalized patients. Which of the following is an appropriate recommendation for. VTE prophylaxis when BG is admitted? A. VTE prophylaxis is not indicated B. Enoxaparin 40 mg SC daily C. Heparin 7,500 units SC Q8H D. Enoxaparin 30 mg SC daily E. Heparin continuous infusion
B. Enoxaparin 40 mg SC daily (p.538)
Method of Preparation: 1. Calculate the quantity of each ingredient. 2. Weigh or measure each ingredient. 3. Use heat to combine the peanut oil, white wax and glycerol monooleate. 4. While the mixture is still soft, add the water in small portions and mix well. 5. When the mixture reaches room temperature, add the rose oil and mix well. 6. Package and label. What is the name of the method used in step 3 of the preparation? A. Compression method B. Fusion method C. Levigation method D. Continental Gum method E. English Gum method
B. Fusion method (p.276)
Medications: Glyburide 5 mg daily Ditropan XL 10 mg daily Norvasc 10 mg daily Prolia 60 mg SC Mirapex 0.125 mg QHS Hydrochlorothiazide 12.5 mg daily Toprol XL 50 mg daily Aricept 5 mg'daily Zoloft 100 mg daily Which of the following combination products contain medications in the same drug class as patient's current hypertension treatments? A. Ziac B. Hyzaar C. Lotrel D. Zestoretic E. Exforge
B. Hyzaar (p.462)
A hospital pharmacy has the following layout for their sterile compounding area. What is the minimum ISO requirement for the ante room? A. ISO 7 B. ISO 6 C. The ante room does not need to have classified air D. ISO 8 E. ISO 5
B. ISO 6 (p.231)
The pharmacist reviews TP's oral medications and realizes that Norvasc and Cozaar are only available in oral form. Which of the following are intravenous antihypertensive medications that can be recommended to control TP's blood pressure? (Select ALL that apply.) A. Lopressor B. Labetalol C. Diovan D. Nifedipine E. Hydralazine
B. Labetalol D. Nifedipine E. Hydralazine (p.472)
Which medication/s on SJ's profile is/are contraindicated? (Select ALL that apply.) A. Nicotine gum B. Phenytoin C. Zyban D. Celebrex E. Cholecalciferol
B. Phenytoin D. Celebrex
The pharmacist in charge at a hospital pharmacy is reviewing the temperature log for the compounding area on February 16th. Based on the temperature log below, on what day/s was the refrigerator or freezer temperature out of range? (select ALL that apply) A. The refrigerator temperature is out of range on February 6th B. The freezer temperature is out of range on February 14th C. The refrigerator temperature is out of range on February 10th D. The refrigerator temperature is out of range on February 8th E. The freezer temperature is out of range on February 10th
B. The freezer temperature is out of range on February 14th C. The refrigerator temperature is out of range on February 10th (p.238)
Which of the following counseling instructions should be provided for the prescription HB is getting filled today? A. If you do not feel a "tingly" feeling as the tablet dissolves, use another tablet B. This medication should be kept in the original amber glass bottle and stored at room temperature C. Chew and svtallow one tablet every 5 minutes x 3 tablets; call 911 if chest pain persists after the first tablet is taken D. Use one tablet every 5 minutes x 3 tablets; call 911 if chest pain persists after the third tablet is taken E. This medication is good for 60 days after the bottle has been opened
B. This medication should be kept in the original amber glass bottle and stored at room temperature
Which medication is an incretin analog which causes increased insulin secretion, decreased glucagon secretion, improved satiety and weight loss in many patients? A. Fortamet B. Trulicity C. Actos D. Invokana E. Amaryl
B. Trulicity (p.649)
TM is a 10-month-old child with a viral-induced fever. He weighs 15.4 pounds. His parents report that he has been crying all day and the pediatrician has recommended acetaminophen. He has a fever of 39.4°C. Which of the following dosing recommendations for acetaminophen for this child is correct? A. 160 mg every 4-6 hours as needed B. 100 mg every 2-4 hours as needed C. 80 mg every 4-6 hours as needed D. 150 mg every 8 hours as needed E. 40 mg every 4-6 hours as needed
C. 150 mg every 8 hours as needed (p.765)
FW is a 47-year-old male Height: 5'7" Weight: 152 lbs Six months later, FW presents to the clinic with declining health. His CD4 count has increased and he is diagnosed with cytomegalovirus retinitis. His renal function is unchanged but his weight has dropped to 142 lbs. Which induction dose of valganciclovir is appropriate for FW? Valganciclovir Dosing Recommendations: CrCl >= 60 mL/min: 900 mg twice daily CrCI 40-59 mL/min: 450 mg twice daily CrCI 25 39 mL/min: 450 mg once daily CrCI 10-24 mL/min: 450 mg every 2 days CrCl < 10 mL/min: Not recommended A. 450 mg once daily B. 900 mg twice daily C. 450 mg twice daily D. Valganciclovir is not recommended for FW E. 450 mg every 2 days
C. 450 mg twice daily (p.175)
A patient is starting hemodialysis and a new order is written for Venofer. The healthcare providers in the hemodialysis unit should monitor the patient for which of the following side effects? A. Peripheral neuropathy B. Hepatotoxicity C. Anaphylaxis D. Dyskinesia E. QT prolongation
C. Anaphylaxis (p.545)
The diagnostic test reported on SJ's profile is used to evaluate which of the following conditions? A. Peripheral neuropathy B. Readiness to quit smoking C. Depression D. Cardiovascular risk E. Seizure disorder
C. Depression
What is likely to occur when FW's PCP prophylaxis is discontinued? A. His INR will decrease B. His HIV viral load will increase C. His CD4 count will inciease D. His INR will increase E. His HIV viral load will decrease
C. His CD4 count will inciease (p.535)
On October 14th, a 13-month-old child was hospitalized for 4 days for a flare of polyarticular juvenile rheumatoid arthritis. During the hospitalization her rheumatologist adminstered IV steroids, nonsteriodal anti-inflammatory drugs and Gammagard (IV immunoglobulin) to manage the flare. The child is now scheduled for a visit with her pediatrician to catch up on several vaccinations, including Varivax. On which date will it be safe to administer Varivax to this child? A. November 28th B. October 28th C. January 28th D. December 28th E. November 14th
C. January 28th (p.318)
eGFR = 40 mL/min/1.73m2 LD develops a urinary tract infection. The pharmacist is consulted to review her profile and make a recommendation, Which of the following antibiotics is contraindicated in LD? A. Augmentin B. Ertapenem C. Nitrofurantoin D. Cephalexin E. Bactrim DS
C. Nitrofurantoin (p.368)
A critically ill patient has the following arterial blood gas. What acid-base disturbance is occurring? pH = 7.27 PCO2 = 54 mmHg (35 - 45 mmHg) pO2 = 78 mmHg (80 - 100 mmHg) HCO3 = 27 mEq/L (22 26 mEq/L) A. Respiratory alkalosis B. There is no acid-base disorder C. Respiratory acidosis D. Metabolic acidosis E. Metabolic alkalosis
C. Respiratory acidosis (p.177)
Which of the following compounded preparations must be prepared in a negative pressure hood? A. Vardenafil sublingual films B. Valacyclovir lip ointment C. Tacrolimus oral suspension D.Naltrexone suppositories E. Donepezil emulsion
C. Tacrolimus oral suspension (p.229)
DL's physician plans to begin treatment for hepatitis. Which medication/s should be avoided in combination with DL's acid-suppressive therapy? (Select ALL that apply.) A. Epclusa B. Harvoni C. Tenofovir alafenamide D. Viread E. Ribavirin
C. Tenofovir alafenamide E. Ribavirin (p.305)
Labs: (4/13) aPTT: 82 sec (22-38 sec) Based on the laboratory findings on April 13th, SZ is likely experiencing an adverse reaction to which medication? A. Lasix B. Procardia XL C. Неparin D. Digoxin E. Aldactone
C. Неparin (p.530)
The pharmacist is compounding the ointment below. Cooling Ointment (Water-in-Oil) Ingredients: Peanut oil 57.5 g White wax 12.5 g Glycerol monooleate 5 g Rose oil 1 drop Water 25 g What is the most likely HLB number for glycerol monooleate? A. 11.4 B. 18.6 C. 15.2 D. 3.8 E. 22.1
D. 3.8 (p.257)
TP's laboratory findings show evidence of: A. Metabolic acidosis B. An allergic reaction C. Thrombocytopenia D. A left shift E. Anemia
D. A left shift (p.73)
Which of the following antibiotics can be safely prescribed for a patient who required intubation after receiving amoxicillin as a child? A. Zosyn B. Avelox C. Invanz D. Augmentin E. Teflaro
D. Augmentin (p.348)
Allergies: Sulfa drugs (chest and abdomen turn "beet red" and itchy) Which medication for primary prophylaxis should be added to CL's profile? A. Dapsone B. Valganciclovir C. Biaxin D. Bactrim DS E. Fluconazole
D. Bactrim DS (p.413)
Which of the following inhalers are dry powder inhalers? (Select ALL that apply.) A. Flovent HFA B. Spiriva Respimat C. ProAir RespiClick D. Breo Ellipta E. Advair Diskus
D. Breo Ellipta E. Advair Diskus (p.607)
Each of the following drugs are active against MRSA except: A. Linezolid B. Daptomycin C. Vancomycin D. Ceftriaxone E. Ceftaroline
D. Ceftriaxone (p.369)
Which of LY's home medications requires a dose reduction due to the risk of QT prolongation? A. Keflex B. Entacapone C. Benicar D. Celexa E. Furosemide
D. Celexa (p.883)
A patient is receiving vancomycin 1250 mg IV Q12H for treatment of MRSA pneumonia. A trough serum level drawb immediately before tve the 5th dose was 12 mcg/mL. What should the pharmacist recommend? A. Switch to tobramycin B. Decrease the dose C. Increase the dose D. Continue current treatment E. Switch to meropenem
D. Continue current treatment (p.361)
What is the antidote for iron overdose? A. Dexrazoxane B. N-acetyicysteine C. Andexanet alfa D. Deferoxamine E. Cyanocobalamin
D. Deferoxamine (p.1037)
Which medication on BG's home medication list is most likely responsible for the ECG results? A. Dofetilide B. Fludrocortisone C. Finasteride D. Donepezil E. Warfarin
D. Dofetilide (p.508)
Medications: Complera 1 tab QD Which of the following ingredients are contained in FW's antiretroviral treatment? A. Abacavir lamivudine + dolutegravir B. Emtricitabine + tenofovir disoproxil fumarate + elvitegravir + cobicistat C. Emtricitabine + tenofovir alafenamide D. Emtricitabine + tenofovir disoproxil fumarate + rilpivirine E. Efavirenz + tenofovir alafenamide + rilpivirine
D. Emtricitabine tenofovir disoproxil fumarate + rilpivirine (p.419)
A mother brings her 18-month-old child to the pediatrician. The child is fussy, and upon examination the pediatrician notes stridor and barking cough. A diagnosis of croup is made. Which of the following treatments is recommended? A. Palivizumab B. Dexamethasone C. Vancomycin + cefotaxime D. Guaifenesin/codeine cough syrup E. Desmopressin
D. Guaifenesin/codeine cough syrup (p.768)
PMH: Parkinson disease Atrial fibrillation Mitral valve repair Cerebrovascular accident Moderate-severe Alzheimer's disease Ankylosing spondylitis Cholecystectomy Arthroscopy of the right knee Home medications: Sinemet Donepezil Finasteride Cogentin Midodrine Warfarin Cyanocobalamin Dofetilide Fludrocortisone Soma What condition is missing from BG's past medical history based on his home medication list? A. Deep vein thrombosis B. Addison's disease C. Stroke D. Hypertension E. Schizophrenia
D. Hypertension (p.671)
All of the following medications require monitoring of the absolute neutrophil count EXCEPT: A. Cyclophosphamide B. Clozapine C. Doxorubicin D. Isocarboxazid E. Hydroxyurea
D. Isocarboxazid (p.73)
When DL is nearly ready for discharge, the surgery intern calls the pharmacy for assistance transitioning DL from the PCA to would be most appropriate based on the information below? 24-Hour PCA Report: 0800 - 1200: 6 mg 1201 - 1600: 4 mg 1601 - 2000: 3 mg 2001 - 0000: 2 mg 0001 - 0400: 2 mg 0401 - 0759: 3 mg A. Percocet 7.5/325 mg Q8H B. Percocet 5/325 mg Q4H C. Percocet 7.5/325 mg Q6H D. Percocet 10/325 mg Q6H E. Percocet 5/325 mg Q6H
D. Percocet 10/325 mg Q6H (p.806)
TP is a 52-year-old African America female who was admitted to the hospital 5 daya ago for resection of an abdominal mass. Immunization history: Prevnar 13 & Pneumovax (6 years ago) Influenza During her hospitalization, TP has an immunization screening. Which of the following vaccines should be administered to TP? A. DTAP B. RotaTeq C. Prevnar 13 D. Pneumovax 23 E. Zostavax
D. Pneumovax 23 (p.3220
JN's physician recommends a cough medication to help him sleep. Which cough medication should be avoided in JN? A. Delsym B. Tessalon Perles C. Tussionex D. Robafen DM E. Mucinex
D. Robafen DM (p.564)
A pharmacist will counsel a patient starting allopurinol therapy. Which important side effect should the patient be counseled on? A. Sedation B. Orthostatic hypotension C. Myopathy D. Severe rash E. Injection site reactions
D. Severe rash (p.828)
CT abdomen: diffuse inflammation with some skip areas of small-bowel enteritis and partial small bowel obstruction What is the likely diagnosis given BG's presentation and the results of the CT abdomen? A. Peptic ulcer disease B. Gastroparesis C. Abdominal ascites D. Ulcerative colitis E. Crohn's disease
D. Ulcerative colitis (p.976)
If a patient has a penicillin allergy, the CDC recommends penicillin desensitization followed by penicillin treatment in what scenario? A. An adult patient with bacterial meningitis B. A critically ill patient with sepsis C. A pregnant patient with syphilis D. A pediatric patient with infective endocarditis E. A pediatric patient with acute otitis media
E. A pediatric patient with acute otitis media (p.1007)
A patient with a prosthetic heart valve and history of infective endocarditis needs to have a root canal procedure. The patient has no known drug allergies. Which of the following is recommended for infective endocarditis prophylaxis? A. Ceftriaxone 1 gram B. Azithromycin 1,200 mg C. Vancomycin 1 gram D. Metronidazole 2 grams E. Amoxicillin 2 grams
E. Amoxicillin 2 grams (p.387)
A 12-day-old infant develops symptoms concerning for bacterial meningitis. The medical intern researches common causative pathogens and treatment regimens. She learns that Listeria monocytogenes should be covered in this age group. Which antibiotic in the empiric regimen would cover this organism? A. Cefotaxime B. Vancomycin C. Ceftriaxone D. Gentamicin E. Ampicillin
E. Ampicillin (p.378)
Which of the following represents the primary mechanism of action of dobutamine? A. Phosphodiesterase-3 inhibitor B. Muscarinic antagonist C. Alpha-2 agonist D. Alpha-1 agonist E. Beta-1 agonist
E. Beta-1 agonist (p.755)
The nurse caring for BG is worried because his urine is dark in color. Which of BG's medications is most likely responsible? A. Carbidopa/levodopa B. Donepezil C. Finasteride D. Fludrocortisone E. Dofetilide
E. Dofetilide (p.928)
Which of the following is a recommended initial regimen for HIV that can be administered as a single pill? A. Atazanavir + ritonavir + emtricitabine + tenofovir disoproxil fumarate B. Emtricitabine + elvitegravir + cobicistat + ritonavir C. Raltegravir + bictegravir + emtricitabine D. Lamivudine + abacavir + dolutegravir E. Emtricitabine + tenofovir disoproxil fumarate + efavirenz
E. Emtricitabine + tenofovir disoproxil fumarate + efavirenz (p.419)
A pharmacist is preparing a non-sterile compound. In order to make a homogeneous preparation, a small amount of the active amount of the active infredient is firat mixed throughoutly with an equal amount of the delivery vehicle. This step is repeated by mixing in further equal amounts until the ingredients are incorporated into a uniform mixture. This method of mixing is called: A. Compression molding B. Negative pressure technique C. Trituration D. Pulverization E. Geometric dilution
E. Geometric dilution (p.272)
An oncologist is considering treatment with cetuximab for a patient. Which pharmacogenomic test should be performed prior to prescribing this medication? A. HLA-B*1502 B. HER2 gene expression C. Dihydropyrimidine dehydrogenase deficiency D. Thiopurine methyltransferase activity E. KRAS mutation
E. KRAS mutation (p.1022)
LD's initial labs reveal a serum sodium of 129 mEg/L (range: 135 - 145 mEg/L). Which of LD's medications is most likely responsible? A. Prolia B. Zoloft C. Mirapex D. Aricept E. Toprol XL
E. Toprol XL (p.883)
MO is a 28-year-old, sexually active woman. She recently had a DVT. Which of the following methods of contraception can MO safely use? (Select ALL that apply.) A. Yaz combined oral contraceptive B. Nora-BE mini-pill C. Amethyst extended cycle contraceptive D. Depo-Provera injection E. Xulane patch
E. Xulane patch (p.700)