Pharm Ch. 14

The nurse is assessing an older patient with Parkinson's disease who was started on entacapone 1 week ago. The patient has a history of coronary artery disease and takes an antihypertensive and aspirin. Which information would support the need for a reduction in medication dosage by the healthcare provider?

Dizziness

Dopamine agonists have been linked with which adverse effects in patients with Parkinson's disease?

Sudden sleep events

The nurse is providing education to a patient recently placed on selegiline disintegrating tablets. Which statement by the patient indicates a need for further teaching?

"I will place the tablet on my tongue before breakfast."

The nurse is teaching a patient with Parkinson's disease about levodopa. Which statement by the nurse is accurate regarding drug administration?

"Take this medication with food or antacids to reduce GI upset."

The nurse is preparing to begin administration of apomorphine to a patient. Before administering, the nurse will perform a baseline assessment of the patient's: (Select all that apply.) a. mobility. b. orientation. c. intellectual ability. d. alertness. e. vital signs.

ABDE a. mobility. b. orientation. d. alertness. e. vital signs.

Parkinson's disease has which characteristic symptom(s)? (Select all that apply.) a. Muscle tremors b. Posture alterations c. Muscle flaccidity d. Tachycardia e. Slow body movement

ABE a. Muscle tremors b. Posture alterations e. Slow body movement

Which vitamin will reduce the therapeutic effects of levodopa?

B6

What point(s) should be included when teaching a patient about the use of apomorphine for treatment of Parkinson's disease? (Select all that apply.) a. The restoration of function resulting from stimulation of dopamine receptors is permanent. b. Apomorphine may be administered intravenously for rapid relief. c. Apomorphine does not have any opioid activity. d. A multidose injector pen is commonly used to administer apomorphine. e. You may experience nausea and vomiting, which can be treated with trimethobenzamide (Tigan). f. You may experience sleep attacks or episodes of daytime sleepiness.

CDEF c. Apomorphine does not have any opioid activity. d. A multidose injector pen is commonly used to administer apomorphine. e. You may experience nausea and vomiting, which can be treated with trimethobenzamide (Tigan). f. You may experience sleep attacks or episodes of daytime sleepiness.

What is the rationale for administering levodopa instead of dopamine for treatment of Parkinson's disease?

Dopamine does not cross the blood-brain barrier when administered orally.

The nurse is providing information to a patient recently prescribed entacapone. Which statement is correct?

Dosage is adjusted according to the patient's response.

What is the pharmacologic action of entacapone, a potent catechol O methyl transferase (COMT) inhibitor?

Reduces the destruction of dopamine in peripheral tissues

Which cholinergic symptoms of Parkinson's disease are reduced with anticholinergic drugs?

Tremors and drooling

A patient taking rasagiline is assessed by the nurse to have a lasting significant increase in blood pressure. When reviewing the patient's current list of medications, the nurse decides to hold the next dose of:

ciprofloxacin

When a patient taking a monoamine oxidase B inhibitor receives his dietary tray, the nurse knows to remove the:

cheese

Which adverse effects associated with levodopa therapy would support the nursing diagnosis risk for injury?

orthostatic hypotension