Quiz 2 Blood Ch 17 & Lab 20

Formed elements make up about what percentage of blood?

45%

Aged and damaged erythrocytes are broken down by macrophages in the: spleen. liver. bone marrow. All of the answers are correct. None of the answers is correct

All of the answers are correct

________ is a condition in which the oxygen-carrying capacity of the blood is reduced.

Anemia

A deficiency of vitamin B12 leads to anemia because _________________________.

B12 is essential for normal stem-cell division in the bone marrow

________ transport(s) oxygen and CO 2 in the RBCs.

Hemoglobin molecules

A person with Type A blood has

antigen A on the RBCs and anti-B antibodies in the plasma.

Iron extracted from heme molecules:

binds to transferrin

A person was found trapped in a car that had been running. He was still breathing but had turned blue. A blood test will most likely reveal an abundance of which gas bound to his heme molecules?

carbon monoxide

The function of red blood cells is to

carry oxygen from the lungs to the body's cells.

A substance that activates plasminogen might be useful to

cause clot dissolution to proceed faster.

The common pathway of coagulation begins with the

conversion of Factor X to prothrombin activator.

A physician wanting to determine the types and numbers of each type of leukocyte in a patient's blood would order which test?

differential count

A plasma protein essential for blood coagulation is

fibrinogen

Rouleaux refers to the ability of RBCs to

form stacks.

A hematocrit provides information on

formed elements abundance

All of the following are true of neutrophils except that they are: granular leukocytes. phagocytic. round cells with lobed nuclei. important in coagulation. active in fighting bacterial infections

important in coagulation.

An obstruction in blood flow to the kidneys would ultimately result in

increased erythropoiesis.

Pernicious anemia caused by a lack of intrinsic factor is specifically treated by

injections of vitamin B 12.

Platelet factor (PF-3) is a factor in the ________ pathway.

intrinsic

RBCs typically live about 120 days. The main reason for this short lifespan in RBCs is their

lack of nucleus.

A cancer of the white blood cells is called

leukemia

All of the following are components of the cardiovascular system except: blood. arteries. heart. lymph vessels. capillaries.

lymph vessels.

Which class of formed elements does not arise from myeloid stem cells?

lymphocytes

Platelets are pinched off from giant multinucleated cells in the bone marrow called

megakaryocytes.

Erythropoiesis is stimulated when

oxygen levels in the blood decrease and blood flow to the kidney declines.

Which of the following is not a component of plasma? electrolytes platelets fibrinogen albumin amino acids

platelets

An elevated hematocrit value is termed

polycythemia

All the circulating red blood cells originate in the

red bone marrow

The process of white blood cell production goes on in all of the following except: the spleen. the kidney. the lymph nodes. red bone marrow. the thymus.

the kidney

Most of the protein factors that are required for clotting are synthesized by

the liver

Pooled human plasma (PHP) can be administered to patients by IV infusion for various medical reasons (eg: immunodeficiency, severe blood loss, nutritional deficiency,etc). PHP is derived from 10-30 donors and tested for disease causing agents (eg:HIV) and other biologic/physiologic factors for safety and quality control before it is distributed for use. It is safe to administer PHP to recipients of any blood type without fear of mismatch or rejection reaction, even though PHP is derived from multiple donors. Why is blood type not a concern?

There are at least two reasons. 1. Human plasma does not contain erythrocytes (RBC). RBC are the carriers of the antigen of the ABO and Rh blood groups. Therefore antigen/antibody reaction is unlikely. 2. Since there are multiple donors, antibodies of mismatched donors would react and neutralize antigen molecules that may be present in the PHP before administration to the patient.

All of the following are reasons why a person with type O - blood can safely donate to a person of any blood type except which one?

Type O surface antigens are nonreactive in persons with A, B, or AB blood.