Sodium-Potassium Pump
What is the sodium-potassium pump?
The method by which the neuron regulates the amount of Na+ and K+ inside the membrane - Occurs in the axon of the neurotransmitter
the sodium potassium pump uses _______ transport to move molecules from an area of high [ ] to low [ ]
active
the inside of the cell keeps a __________ charge by only having 2 molecules of potassium after removing 2 sodium
negative - biggest contributor to the negative charge are proteins (make up channels, build materials)
(3) once the potassium ions are bound to the pump, the ________ group detaches which causes the pump to release 2 K ions into the cytoplasm
phosphate - releasing the phosphate allows the channel to revert back to original form and release 2 K ions into the cell
________ carry an inherent negative charge
proteins
(2) once the phosphate from ATP has caused the pump to change shape, the pump __________ 3 Na ions and ______ 2 K ions
releases; binds
the sodium potassium pump is used to maintain _________ potential
resting - the partial negative charge of the inside of the cell is what contributes to this - the cells wants to maintain resting potential
(1) sodium ions bind to the pump and a phosphate group from ATP attaches to the pump, causing it to change its ________
shape
pumps out _________ and replaces with ______________ from the outside
sodium; potassium - 3 Na: 2 K
the cell brings in how many potassium ions?
2 ions
the cell kicks out how many sodium ions?
3 ions
the pump is powered by ____
ATP - for each ATP molecules broken down, 3 sodium ions move out and 2 potassium ions move into the cytoplasm - the splitting of ATP provides energy to change the shape of the channel