Unit 3 - Hemostasis and Anemia

Which is the most abundant protein in plasma? a. Globulins b. Fibrinogen c. Hormones d. Albumin

Albumin

Sickle cell anemia is: a. a recessive genetic disorder b. characterized by a defect in the beta hemoglobin chain c. produces polymerization of hemoglobin that causes the red cell to change shape d. All of these are correct

All of these are correct

Platelets: a. are also known as thrombocytes. b. are actually fragments of cells. c. play a role in preventing blood loss. d. can be stored in, and released from spleen e. All of these choices are correct.

All of these choices are correct.

A man without von Willebrand Factor will have trouble: a. maintaining an adequate Oxygen supply in his blood b. Forming a platelet plug in an injured vessel c. Activating complement to destroy a pathogen d. Creating and breaking down fibrin

Forming a platelet plug in an injured vessel

Which of the following is a specific characteristic of hemolytic anemia? a. Tachycardia b. Hypovolemia c. Pallor d. Jaundice

Jaundice

Vitamin K is important for clotting because: a. The liver needs it to synthesize clotting factors b. without vitamin K, nerves don't fire to alert the body to an injury c. Vitamin K is needed to synthesize the red blood cells and platelets d. Vitamin K is needed to attach the platelets to one another

The liver needs it to synthesize clotting factors

Iron deficiency anemia is most common in: a. adolescents, and pregnant women b. middle-aged men and women c. young and middle-aged men d. older men and women

adolescents, and pregnant women

The hematocrit measures: a. the number of red blood cells b. the hemoglobin content of blood c. the percentage of a given volume of blood that is made up of red cells d. the size of the red blood cells

the percentage of a given volume

The main function of the red blood cell, facilitated by the hemoglobin molecule, is to: a. provide red color to the blood b. transport oxygen to the tissues c. return carbon dioxide from the tissues to the lungs

transport oxygen to the tissues

Hemoglobin: a. gives white blood cells their color. b. transports oxygen in the blood. c. is normally found in both the plasma and erythrocytes. d. catalyzes the reaction that forms carbonic acid. e. is only used once then decomposed.

transports oxygen in the blood.

Plasminogen is important because it: a. can be converted to plasmin, which breaks down fibrin b. can be converted to prothrombin, which helps form clots c. increases the level of clotting factors

can be converted to plasmin, which breaks down fibrin

In hemolytic anemia, low hematocrit is caused by: a. blood loss b. excessive red cell destruction c. iron deficiency d. impaired red cell production

excessive red cell destruction

Erythropoiesis (RBCs production) does not require: a. iron. b. vitamin B12. c. folate. d. vitamin K. e. All of these are required.

vitamin K.

Anemia is most accurately defined as: a. hemorrhage b. low numbers of red blood cells and/or hemoglobin c. red cell hemolysis d. an iron deficiency state

low numbers of red blood cells and/or hemoglobin

Iron deficiency anemia is characterized as: a. normocytic, normochromic b. microcytic, hypochromic c. macrocytic, normochromic d. microcytic, normochromic

microcytic, hypochromic

A patient with atrial fibrillation is prescribed warfarin because it will: a. reduce the risk of clots forming in the atria b. reduce platelet count c. break down any clots that form in the atria

reduce the risk of clots forming in the atria

The process of bilirubin conjugation: a. breaks hemoglobin into bilirubin, globulin chains, and iron b. generates the intermediate 2,3-diphosphoglycerate (2,3-DPG) functions in controlling the affinity of hemoglobin for oxygen c. acts to maintain hemoglobin in the reduced state so that it can function in oxygen transport d. renders lipid-soluble bilirubin from senescent red cells into a water-soluble form

renders lipid-soluble bilirubin from senescent red cells into a water-soluble form

An undetected GI bleed is most likely to cause which kind of anemia? a. iron deficiency b. aplastic c. folic acid deficency d. B12 deficiency

iron deficiency

Erythropoietin: a. is a product of the kidney. b. inhibits the production of erythrocytes. c. is produced in response to increased blood pressure. d. is found both in the plasma and inside red blood cells. e. is produced by the red bone marrow.

is a product of the kidney.

The red blood cell has a life span of approximately: a. 30 days b. 60 days c. 120 days d. 360 days

120 days

Which type of ABO antibodies would a person with type O blood have? a. A b. AB c. B d. O

AB

Sickle cell anemia would be classified as what type of anemia? a. Iron deficiency anemia b. Hemolytic anemia c. Blood loss anemia d. Anemia due to deficient red cell production

Hemolytic anemia

What is the main stimulus for red cell production? a. Hypoxia b. Low iron level c. Exercise d. Senile red blood cells

Hypoxia

Which statement regarding sickle-cell anemia is FALSE? a. The inherited abnormality is manifested as sickle cell trait in those heterozygous for the alteration and as sickle cell disease in those who are homozygous. b. The pain of sickle cell crisis is the result of vessel occlusions. c. People with sickle cell trait experience iron deficiency.

People with sickle cell trait experience iron deficiency.

Which one of the following is not a plasma component? a. Electrolytes b. Platelets c. Gases d. Glucose

Platelets

Mr. J has been diagnosed with anemia. He has the following signs and symptoms; match each with its cause. a. weakness, dizziness, and pallor b. low hematocrit c. bone pain and immature RBCs in his blood d. increased heart rate e. cool, damp skin

a. decreased RBC levels b. decreased RBC levels c. attempt to compensate and increase RBC levels d. GSR e. GSR

In thalassemia, erythrocytes are destroyed rapidly because they have: a. A high O2 affinity b. abnormal hemoglobin molecules c. defective cell membranes d. nuclei

abnormal hemoglobin molecules

Bilirubin is liberated from red blood cells as they are broken down. Which of the following statements is true as it relates to bilirubin? Bilirubin: a. is derived from hemoglobin in red blood cells b. is the pigment that gives bile its color c. can deposit in the skin and eyes d. must be removed from the plasma and conjugated in the liver to render it water soluble so that it can be eliminated in bile e. all of these statements are true

all of these statements are true

Jaundice occurs in: a. diseases that lower serum bilirubin, such as liver disease b. anemias that cause a rapid destruction of red blood cells c. iron-deficiency anemia d. all of these

anemias that cause a rapid destruction of red blood cells

Aplastic anemia is caused by: a. iron deficiency b. a mutation c. bone marrow depression/failure d. lymphoma

bone marrow depression/failure

Which of the following would lead to increased erythropoiesis? a. increased environmental O2 levels b. decreased O2 supply to the kidneys c. increased blood pH d. increased blood pressure e. increased CO2 levels

decreased O2 supply to the kidneys

Which of the following statements is correct about fibrin? a. fibrin is formed from fibrinogen already circulating in the bloodstream b. fibrin is formed from circulating prothrombin c. thromboxane causes the formation of fibrin d. fibrin is synthesized by platelets

fibrin is formed from fibrinogen already circulating in the bloodstream

Conditions that predispose to sickling of hemoglobin in persons with sickle cell anemia are those that: a. impair red blood cell maturation b. increase the iron content of blood c. increase the oxygen content of the blood d. increase the level of deoxygenated hemoglobin

increase the level of deoxygenated hemoglobin

Iron: a. is needed to produce hemoglobin. b. is a plasma coagulation factor. c. is the binding site for carbon dioxide on the hemoglobin molecule. d. prevents carbon monoxide from binding to hemoglobin. e. interferes with the normal function of hemoglobin.

is needed to produce hemoglobin.

Vit B12 is needed for RBC production because it: a. is required for the RBCs to mature b. is needed to create hemoglobin c. Stimulates the bone marrow to produce cells d. Causes the iron levels in the blood to increase

is required for the RBCs to mature

The hormone erythropoietin, which stimulates red blood cell production in the bone marrow, is produced by: a. red blood cells b. liver c. kidney d. bone marrow

kidney

A patient with a stroke was given tissue plasminogen activator (t-PA) instead of heparin. Why? a. t-PA activates plasmin, which breaks down the clot b. t-PA and heparin do the same thing, but t-PA is given if the stroke has only happened a few hours ago c. t-PA can increase blood clotting

t-PA activates plasmin, which breaks down the clot

An increase in hemoglobin increases a. the ability of the blood to carry oxygen to various tissues. b. the quantity of plasma protein available for blood clotting. c. the leukocyte count. d. the body's immune response. e. the osmotic pressure of the blood.

the ability of the blood to carry oxygen to various tissues.

The cause of pernicious anemia is: a. the absence of extrinsic factor b. the absence of intrinsic factor c. lack of vitamin B12 in the diet d. Iron deficiency

the absence of intrinsic factor

What is thrombin? a. the enzyme that converts circulating fibrinogen into fibrin b. one of the clotting factors made by the liver c. an adhesion protein that allows platelets to stick to blood vessels d. the enzyme that breaks down clots

the enzyme that converts circulating fibrinogen into fibrin

Plasma is ____ while formed elements are ____. a. a blood gas; blood clots b. the liquid portion of blood; the cells c. lacking in protein; regulators of blood osmolality d. the cellular portion of blood; acellular components e. mostly protein; the matrix

the liquid portion of blood; the cells

A man with liver failure developed excessive bleeding. Why? a. the liver is responsible for making clotting factors b. the liver is needed to absorb iron c. the liver destroys aldosterone, making the blood thicker and easier to clot d. the liver produces platelets

the liver is responsible for making clotting factors