Unit 3 Pharm Review

A nurse is instructing a client how to self-administer enfuvirtide. Which instruction should the nurse include?

"Allow the vial to sit until the solution is completely clear and without particulates." When administering enfuvirtide, the client should inject sterile water to reconstitute it and gently roll the vial between the hands

A nurse is teaching a client about maraviroc. Which instruction should the nurse include?

"It is important to report any noticeable rash immediately as it might indicate an issue with your liver." Hepatic injury can manifest as a rash in clients who take maraviroc and should be reported to the provider regardless of how mild it appears

A nurse is teaching a client who has a new prescription for quinidine. Which statement should the nurse include?

"Monitor your pulse rate and report changes." Sodium channel blockers, like quinidine, can worsen dysrhythmias, or cause new ones. The nurse should teach the client to monitor their pulse rate and report changes from prescribed parameters; it can be helpful to instruct the client to keep a written record of their pulse rate for the provider

A nurse is teaching a client about immunizations. Which information should the nurse include in the teaching?

"You should receive a tetanus booster every 10 years." The nurse should inform the client that the tetanus-diphtheria (Td) vaccine is recommended every 10 years

A nurse is caring for a client who has a new prescription for dobutamine. The nurse should clarify the prescription with the provider if the client is receiving which types of drugs? Select all that apply

- Monoamine oxidase inhibitor (MAOI); cause toxicity when clients taking them also receive dobutamine; client is at risk for tachydysrhythmias which increases significantly - General anesthetic; cause dysrhythmias - Tricyclic antidepressant; cause toxicity - Beta blocker; decreases the effects of dobutamine

A nurse is preparing to administer enfuvirtide to a client. Which actions should the nurse plan to perform? Select all that apply

- administer the drug subcutaneously; only appropriate rout of administration of enfuvirtide - roll vial gently to reconstitute solution - inject solution at room temp

A nurse is caring for a client who will begin using transdermal nitroglycerin to treat angina pectoris. When speaking to the client about the drug, which of the following instructions should the nurse include? Select all that apply

- apply the patch to a hairless area and rotate sites; hair can interfere with the adhesion of the patch; rotating sites helps prevent skin irritation - apply a new patch when you start your day; therapeutic preventive effects of transdermal nitroglycerin patches begin 30 to 60 min after application and last up to 14 hours; because angina pain is more likely with activity; most patients require this protection during waking hours - remove patches for 10-12 hours daily; removing the patches for 10-12 hours each day helps prevent tolerance to the drug; for most clients; sleeping hours are the best time to go "patch free," as angina pain is more likely during activity

A nurse is teaching a client who has a new prescription for imatinib to treat myeloid leukemia. Which instructions should the nurse include? Select all that apply

- clean fruits and veggies thoroughly; prevents transmission of bacteria - weight yourself daily; imatinib can cause fluid retention and weight gain; tell patient to watch for edema - perform hand hygiene frequently; prevents exposure to illness - avoid grapefruit and grapefruit juice; could cause the blood levels of imatinib to be higher than normal

A nurse is teaching a client about taking ferrous sulfate to treat iron deficiency anemia. Which instruction should the nurse include? Select all that apply

- eat iron-enriched foods; clients who have iron deficiency anemia should increase iron intake with foods such as egg yolks, wheat germ, meat, and fish to supplement ferrous sulfate - spread the dosage across each day; spreading out the iron intake throughout clients' waking hours allows the bone marrow to maximize production of RBCs - take the drug on empty stomach; food reduces the absorption of ferrous sulfate; clients should take drug on an empty stomach to increase drug absorption; if GI effect are troublesome, clients can take drug with food - increase dietary fiber intake; ferrous sulfate can cause constipation; clients should increase fiber and fluid intake and exercise more often or more intensely

A nurse is preparing to administer paclitaxel IV to a client who has ovarian cancer. Which actions should the nurse take? Select all that apply

- give the patient an antihistamine; prevents client from having a hypersensitivity reaction - administer the drug through non-PVC tubing; this drug is compatible with PVC tubing - use an in-line filter; the drug requires administration through an in-line filter

A nurse is caring for a client who has a new prescription for aliskiren to treat hypertension. The nurse should monitor the client for which findings as an adverse effect of the drug?

- hyperkalemia; elevated potassium levels; aliskiren can can this in combination with an ACE inhibitor, potassium supplements, or potassium-sparing diuretics; nurse should obtain potassium level at baseline - throat swelling; angioedema (swelling of the mouth and throat); this can be caused at any time during course of therapy; clients who develop this adverse effect should stop taking the drug and seek medical attention - cough; aliskiren can also cause this

A nurse is caring for a client who has a new prescription for maraviroc therapy. The nurse should instruct client to report which adverse effects?

- paresthesia; also dizziness and musculoskeletal pain - cough; also upper respiratory infection - jaundice; maraviroc can cause liver damage; also report allergic reaction, such as a rash, because it could precede liver damage; manifested as jaundice or abdominal pain - fever; also sinus infection

A nurse is caring for a client who has a new prescription for cisplatin to treat testicular cancer. The nurse should instruct the client to report which adverse effects? Select all that apply

- paresthesias; nurse should tell the client to report numbness, tingling, or decreased sensation in the hands or feet - sore throat; cisplatin can cause bone marrow depression; the nurse should tell the client to report fever, sore throat, bruising, or fatigue - flank pain; cisplatin can cause kidney toxicity; prior to therapy, the nurse should hydrate the client with 1 to 2 L of IV fluid and continue for 24 hr following therapy to flush kidneys and help prevent indications of kidney toxicity, such as flank pain - tinnitus; cisplatin can cause ototoxicity; the nurse should monitor for the client's hearing, and tell him to report hearing loss, vertigo, or tinnitus

A nurse is caring for a client who is about to begin captopril therapy. Which of the following adverse effects should the nurse instruct the client to report because if can indicate a need to discontinue drug therapy? Select all that apply

- rash; often indicates the need to stop drug therapy - distorted taste; distortions in taste sensations can be caused which are often salty or metallic which could lead to anorexia and weight loss - swelling of the tongue; angioedema; also manifesting swelling of the pharynx and glottis; client should seek medical attention - dry cough; because of an accumulation of bradykinin

A nurse is teaching a client who has a new prescription for gemfibrozil. Which instructions should the nurse include? Select all that apply

- report any new tolerance to fried foods; also any new tolerance to bloating or upper abdominal discomfort - report muscle tenderness; myopathy; clients should monitor or report any unexplained muscle or joint pain - expect periodic liver function testing; nurse should monitor liver function of patients taking the drug

A nurse is teaching a client who has a new prescription for mercaptopurine to treat leukemia. Which instructions should the nurse include? Select all that apply

- use contraception if pregnancy is at risk; pregnancy risk category D drug - perform oral hygiene frequently; mercaptopurine can cause stomatitis; instruct client to perform oral hygiene to help prevent or minimize this adverse effect - perform hand hygiene frequently; also avoid crowds and contact with people who have communicable infections - avoid activities that can cause injury; tell the patient which activities can cause injury and report easy or unexplained bruising or bleeding

A nurse is assessing a client following a trastuzumab infusion to treat metastatic breast cancer. Which finding should the nurse recognize as an indication that the client is experiencing an adverse reaction to the drug? Select all that apply

- wheezing; trastuzumab can cause a severe allergic reaction, manifesting as hives, bronchospasm, dyspnea, and wheezing; nurse should have epinephrine ready to treat anaphylaxis - dysthymias; this drug can cause cardiotoxicity, manifesting as ventricular dysfunction, heart failure, and dysthymias; nurse should monitor client's ECG - hypotension; this drug can cause a severe allergic reaction, manifesting as hives, dyspnea, hypotension, and hypoxia; nurse should have epinephrine to treat anaphylaxis - fever; this drug can cause flu-like reactions, manifesting as fever, chills, nausea, and headache; nurse should monitor client's temp

A nurse is teaching a guardian of a child about the recommend age range receive the human papillomavirus (HPV) vaccine. Which of the following age ranges should the nurse include?

11-12 years old Three doses of the vaccine for HPV are recommended for adolescents ages 11 to 12

A nurse is caring for a client who is experiencing an acute ischemic cerebrovascular right event due to a thrombus in a cerebral vessel. Which drug should the nurse expect to administer?

Alteplase Alteplase can dissolve existing thrombi, whereas anticoagulant/anti-platelet drugs do not; an acute ischemia cerebrovascular even is often caused by the occlusion of a cerebral vessel by a thrombus; administration of alteplase should be within 3 hour of the original onset symptoms for the drug to be effective

A nurse is caring for a client who is taking digoxin and develops changes on their ECG tracing and other manifestations that indicate the client has severe digoxin toxicity. Which drug should the nurse expect to administer to treat this complication?

Antigen-binding fragments Also called digoxin immune fab, binds to digoxin and blocks its action; nurse should prepare to administer this antidote IV to clients who have severe digoxin toxicity

A nurse should recognize that maraviroc is used in the treatment of which condition?

Chemokine receptor 5 (CCR5)-tropic HIV-1 Maraviroc prevents HIV-1 from entering the cell; contraindicated for those who don't have CCRS-tropic HIV-1

A nurse is caring for a client who has chronic stable angina. The nurse should identify that which drug inhibits the action of adenosine diphosphate receptors (ADP) on platelets and can be prescribed to reduce the client's risk for myocardial infarction?

Clopidogrel This medication blocks the ADP receptors on platelets, preventing platelet aggregation; this effect is irreversible and lasts the lifespan of the platelets (7-10 days)

A nurse is caring for a client who is about to begin therapy with recombinant factor IX to treat hemophilia B. The client asks the nurse about the risk of disease transmission with recombinant factor IX as compared with plasma-derived factor IX. The nurse should explain that recombinant factor IX practically eliminates the risk for what?

Creutzfeldt-Jakob disease Recombinant factor IX is safer than the plasma derived formulation because of the risk of the Creutzfeldt-Jakob disease, a prion-transmitted infection, from human resources; plasma derived products also carry a minimal risk of acquiring hepatitis A and parvovirus B19

A nurse is teaching a client who has a new diagnoses of breast cancer about the drug tamoxifen. The nurse should tell the client that which condition is a contraindication for taking tamoxifen?

Deep-vein thrombosis Tamoxifen, an estrogen receptor blocker, can cause thromboembolism; its use requires cautious use with clients who have deep-vein thrombosis

A nurse is caring for a client who is taking ferrous sulfate to treat iron-deficiency anemia and develops iron toxicity. Which drug should the nurse expect to use to treat this complication?

Deferoxamine (Desferal) Indications of iron toxicity include nausea, vomiting, and diarrhea; iron toxicity can lead to acidosis and shock; a cheating agent, such as deferoxamine, binds to the iron to reduce toxicity

A nurse is caring for a client who has a new prescription for intrathecal cytarabine therapy to treat meningeal leukemia. The nurse should inform the client that they will also receive which drug to reduce risk of neurotoxicity?

Dexamethasone Helps decrease inflammation of the arachnoid that the drug can cause, IV dexamethasone reduces patient's risk for neurotoxicity

A nurse is teaching the guardian of a 4-month-old infant about recommended immunizations for the infant. Which immunization should the nurse include?

Haemophilus influenzae type B vaccine (Hib) The nurse should inform the guardian that the Haemophilus influenzae type B vaccine (Hib) is recommended for infants and children to prevent a serious type of meningitis commonly seen in young children

A nurse is caring for a client who is prescribed zidovudine. Which lab value should the nurse report to the provider?

Hemoglobin 71 g/dL The provider might consider dose reduction, discontinuation of therapy, or blood transfusions if the client's hemoglobin is less than 7.5 g/dL or has a reduction of greater than 25% from baseline

A nurse is reviewing the medication record of a client who is receiving alteplase following an acute myocardial infarction (MI). Which medication should the nurse expect the client to be taking in addition to the alteplase?

Heparin Heparin therapy should be initiated before alteplase therapy and continued at least 48-72 hours after the fibrinolytic therapy to reduce the risk of additional clot formation

A nurse is teaching a client about recommended immunizations. Which immunization should the nurse recommend the client to receive starting at 50 years of age?

Herpes zoster vaccine The herpes zoster, or shingles vaccine, is recommended for adults older than 50 years of age

A nurse is caring for a client who is about to begin takin epoetin. An increase in which of the following lab values should indicate to the nurse that the therapy is effective?

Hgb Epoetin alfa, an erythropoietic growth factor, increases the production of RBCs for clients who have anemia due to chronic renal failure or chemotherapy; Hgb and Hct should increase with effective therapy

A nurse is caring for a client who has a new prescription for topotecan therapy to treat resistant, small-cell lung cancer. The nurse should advise the client against taking which type of over-the-counter drug while receiving the therapy?

Ibuprofen (Advil) the nurse should advise the patient against taking aspirin, ibuprofen, and other NSAIDS during therapy

A nurse is caring for a client who has a new prescription for propranolol to treat tachydysrhythmias. The nurse should instruct the client to avoid taking which type of over-the-counter drug while taking propanolol?

NSAIDS NSAIDS can interact with propranolol and decrease the anti-hypertensive action because in some COX-2 inhibitors, vasoconstriction can occur. Nurse should instruct client to avoid taking NSAIDS and propranolol at the same time

A nurse is caring for a client who is taking spironolactone to treat hypertension. The nurse should recognize that which client lab values requires immediate intervention?

Potassium 5.2 mEq/L potassium level is outside the expected reference range of 3.5 to 5.0 mEq/L and requires immediate intervention

A nurse should identify that which drug is used only for the short-term treatment of a cardiac dysrhythmia because of the serious adverse effects associated with long-term use?

Procainamide Procainamide, a sodium channel blocker and a broad-spectrum antidysrhythmic, is a poor choice for long-term control of dysrhythmias because of its risk for serious adverse effects, including cardiotoxicity and arterial embolism

A nurse is caring for a client who has a depressive disorder and requires a prescription drug to treat hypertension. The nurse should recognize that which antihypertensive drug is contraindicated for this client?

Reserpine Severe depression and an increased risk for suicide are adverse effects of adrenergic neuron blockers, such as reserpine; these adverse effects develop because of the depletion of serotonin and norepinephrine and can persist after clients discontinue this drug

The nurse is caring for a client who has a new prescription for verapamil. The nurse should clarify prescription with the provider if the client has a history of which of the following conditions?

Second-degree AV block Also contraindicated for those who have sick sinus syndrome; indicated for hypertension, angina pectoris, and the management of atrial flutter and fibrillation; also prescribed for the management of migraine headaches

A nurse is reviewing new prescriptions with a client who has heart disease. The nurse should instruct the client that which drug is prescribed to treat hypercholesterolemia?

Simvastatin blocks synthesis of cholesterol by the body to help lower cholesterol levels

A nurse is considering drug therapy options for a client who has metastatic breast cancer that is positive for human epidermal growth factor receptor 2 (HER2). Which drug should the nurse expect the provider to prescribe?

Trastuzumab (Herceptin)

A nurse should assess a client who has megaloblastic anemia for indications for which vitamin deficiency?

Vitamin B12 Clients who have megaloblastic anemia have a deficiency of vitamin B12, folic acid, or both. Cyanocobalamin (Nascobal) treats moderate vitamin B12 deficiencies; clients who have a severe vitamin B12 deficiency should take cyanocobalamin and folic acid

A nurse in an emergency department is assessing a client who has been taking warfarin and is experiencing rectal bleeding. Which drug should the nurse expect to administer to the client?

Vitamin K Vitamin K reverse the effects of warfarin by promoting the synthesis of coagulation factors VI, IX, X, and prothrombin

A nurse should recognize that milrinone is contraindicated for a client who has which condition?

acute myocardial infarction also for clients who have aortic or pulmonary valve disorders

A nurse is administering epoetin IV to a client who has renal failure. Which of the following actions should the nurse take?

administer via IV bolus over 1-3 min Instructions for administering the drug include administering it via IV bolus for over 1 to 3 minutes

A nurse should recognize that enfuvirtide can be prescribed to clients who have which condition?

advanced HIV disease nurse should always give the drug along with other antiretroviral drugs

A nurse is caring for a client who is about to begin alteplase therapy to treat pulmonary embolism. Which drug should the nurse have available in the event of severe adverse reaction?

aminocaproic acid (Amicar) Aminocaproic acid, a coagulator, inhibits fibrinolysis and stops fibrinolytic bleeding, patients often require blood replacement

A nurse is preparing to administer the measles, mumps, and rubella (MMR) vaccine to a child. The nurse should recognize that the MMR vaccine provides which type of immunity?

artificial active immunity The nurse should recognize that the MMR vaccine provides artificial active immunity to the child. A vaccine contains a form of the disease that is live, attenuated, or killed, which will allow the body to build up an active immunity against the diseases

A nurse is preparing to administer a prescribed dose of desmopressin to a client who has hemophilia A. The client's lab results indicate that the client has a sodium level of 130 mEq/L. Which action should the nurse take?

clarify the prescription with the provider The clients sodium level is below the expected range of 135-145 mEq/L; the nurse should notify the provider of the clients sodium levels and clarify the prescription prior or to administration

A nurse is monitoring a client following ferrous sulfate administration. The nurse should monitor the client for which adverse effect?

constipation oral iron supplementation is associated with constipation; the nurse should encourage the client to consume adequate amounts of fiber and fluids in their diet to minimize this effect

A nurse is teaching a client who is starting treatment with warfarin. The nurse should plan to include info on which topic to promote the effectiveness of the drug?

dietary modifications Warfarin is an anticoagulant drug that functions by inhibiting the action of Vitamin K. Many foods, such as green, leafy veggies, are rich in Vitamin K; client should maintain a consistent intake of vitamin K to avoid excess or deficits and ensure therapeutic effects of warfarin are consistent

A nurse is caring for a client who has hemophilia A and is about to begin taking desmopressin to prevent bleeding. The nurse should monitor the client for which adverse reaction?

edema Desmopressin, an anti-diuretic hormone, can cause fluid retention; HCP should monitor fluid intake and output for clients receiving the drug therapy

A nurse is caring for a client who is taking filgrastim to treat neutropenia. The nurse should assess the client for which adverse effect?

enlarged spleen With long-term use, filgrastim, a leukopoietic growth factor, can cause an enlarged spleen; the nurse should tell clients who are taking the drug to monitor and report abdominal pain or fullness

A nurse is providing teaching to a client who has a new prescription for losartan to treat hypertension. The nurse should instruct the client that which finding could indicate an adverse reaction to the drug and needs to be reported?

facial edema Often manifests as redness and swelling around the eyes and lips; clients who develop this adverse effect should stop taking the drug and seek medical attention

A nurse is caring for a client who is taking amiodarone to treat atrial fibrillation. What should the nurse instruct the client to avoid while taking this drug?

grapefruit juice grapefruit juice, particularly in large amounts, can cause toxicity of potassium channel blockers, such as amoidarone

A nurse is caring for a client who is about to begin factor VIII therapy to treat hemophilia A. When administrating factor VIII, which action should the nurse take?

have emergency equipment ready Factor VIII can cause a hypersensitive reaction and anaphylaxis; the nurse should monitor for hives, fever, wheezing, and difficult breathing, as well as having emergency equipment and drugs available

A nurse is teaching a client who has a new prescription for nitroglycerin. The nurse should instruct the client that which manifestation is a potential adverse effect of this drug.

headache adverse effects of nitrates, such as nitroglycerin, include headaches, which can be severe at the beginning of nitrate therapy but decreases in severity with continued exposure to nitrates

A nurse is caring for a client who recently star aged alteplase therapy. The nurse should monitor the client for which adverse effect?

headache Alteplase, a thrombolytic drug, can cause intracranial bleeding, monitor clients receiving the drug for changes in level of consciousness, headache, one-sided weakness, and other indications of intracranial bleeding

A nurse is caring for a client who has renal failure and is receiving epoetin. The nurse should monitor the client for which adverse effect?

hypertension Epoetin alfa, an erythropoietic growth factor, can cause hypertension; the nurse should monitor blood pressure and regulate it prior to initiating epoetin alfa therapy, then monitor it during therapy; for elevations, recommend a reduced dosage or antihypertensive drug therapy

A nurse is administering hydrochlorothiazide to a client who has gouty arthritis. The nurse should monitor the client for which finding that indicates an adverse effect of this drug?

hyperuricemia increased uric acid levels; along with gouty arthritis can occur in clients who have history of these conditions and are taking hydrochlorothiazide

A nurse is caring for a client who is taking carvedilol and has a prescription for an oral anti-diabetic drug to manage their new diagnosis of type 2 diabetes mellitus. By taking both drugs concurrently, the nurse should identify that the client is an increased risk for which condition?

hypoglycemia two factors increase the client's risk for hypoglycemia; alpha/beta blockers, such as carvedilol, potentiate the hypoglycemic effects of insulin and oral hypoglycemic drugs; also, carvedilol can mask tachycardia in a patient who has hypoglycemia; using carvedilol with patients who have diabetes mellitus requires caution

A nurse is assessing a client who is taking a loop diuretic and is experiencing a thready, irregular pulse, orthostatic hypotension, and confusion. The nurse should identify that these manifestations indicate which adverse effect?

hypokalemia Manifestations of hypokalemia include a thready, irregular pulse, orthostatic hypotension, anxiety, confusion, skeletal muscle weakness hypoactive bowl sounds, polyuria, nausea, and vomiting

A nurse is caring for a client who has a new prescription for verapamil to treat atrial fibrillation. The nurse should instruct the client to avoid drinking verapamil because it can cause the client to experience which condition?

hypotension large amounts of grapefruit juice increases blood levels of verapamil by inhibiting its metabolism. The excess amount of drug can intensify otherwise therapeutic effects like hypotension, causing serious risks for syncope and dizziness

A nurse is caring for a client who is about to begin taking aspirin to reduce the risk of cardiovascular event. The nurse should identify that the drug inhibits platelet aggregation by which mechanism?

inhibiting cyclooxygenase action in platelets salicylates, such as aspirin, work by inhibiting platelet aggregation; they do this by blocking the action of cyclooxygenase on platelets; as a result, activation of thromboxane A2 does not occur

A nurse is providing teaching to a client who is taking simvastatin. The nurse should instruct the client to report which manifestation as an indication of a serious adverse reaction that could require discontinuing drug therapy?

muscle pain Simvastatin, an HMG-CoA reductase inhibitor (statin), can cause myopathy or pain in muscles and joints that can progress to rhabdomyolysis. With this rare but serious adverse effect, muscle protein breaks down and its excretion causes kidney damage

A nurse is caring for a client who is taking atorvastatin and has a new prescription for gemfibrozil. The nurse should recognize that this drug combination places the client at an increased risk for which adverse effect?

myopathy When taking a statin drug, it is important to know that concurrent use of fabric acid derivatives, or other drugs to lower cholesterol, can increase risk of myopathy

A nurse should identify that clopidogrel is contraindicated for clients who have which condition?

peptic ulcer disease clients who have peptic ulcer disease should not take clopidogrel, because it can cause gastric bleeding

A nurse is caring for a client who is taking a diuretic. The nurse should instruct the client to include which food in their diet to increase potassium intake?

raisins diuretics can deplete the body of potassium, so the nurse should instruct the client to include potassium-rich foods in their diet; such as raisins and other dried foods

A nurse is monitoring a client who is undergoing anticoagulant therapy with heparin. Which finding should the nurse identify as a possible indication of hemorrhage?

rapid pulse tachycardia is a compensatory mechanism of the heart that serves to combat the hypotension that results from the decreased volume of blood; tachycardia can be detected by checking the pulse

A nurse is caring for a client who has a new prescription for delavirdine therapy to treat HIV-1. The nurse should instruct the client to report which adverse reaction to the drug?

rash The nurse should tell the client to report a rash, which could occur 1-3 weeks after therapy, because it can develop into Stevens-Johnson syndrome, a potentially life threatening complication

A nurse should recognize that raltegravir is used to treat clients who have what?

resistant HIV disease Raltegravir treats HIV disease that is resistant to other drugs; the nurse should always give the drug along with other antiretroviral drugs

A nurse is caring for a client who is about to begin taking folic acid to treat megaloblastic anemia. The nurse should monitor which lab balances to determine therapeutic effectivness?

reticulocyte count A reticulocyte measures the amount the immature RBCs; folic acid, also called folate, is essential for erythropoiesis. Clients who have a folic acid deficiency require a baseline reticulocyte count, as well as serum folate, Hgb, Hct, RBC count and periodic during folic acid and therapy to determine effectiveness

A nurse is caring for a client who has a glomerular filtration rate of 10 mL/min and a reduced urine output. The nurse should clarify a prescription for hydrochlorothiazide for this client because of which characteristic of the drug?

the drug does not promote diuresis for clients who have renal insufficiency adequate kidney function is essential for hydrochlorothiazide, a thiazide diuretic, to promote urine production and excretion effectively

A nurse is caring for a client who is taking clopidogrel to prevent stent restenosis. The nurse should monitor the client for which adverse reaction?

thrombocytopenia nurse should monitor platelet count, bruising, bleeding gums, and petechiae

A nurse is caring for a client who has a new prescription for ritonavir and zidovudine therapy to treat HIV-1. The nurse should inform the client that zidovudine is prescribed with ritonavir for what reason?

to prevent drug resistance

A nurse is caring for a client who is scheduled for an outpatient surgical procedure and reports taking aspirin 81 mg daily, including this morning. The nurse should identify that this places the client is at risk for which complication?

uncontrolled bleeding Aspirin is a salicylate (anti-platelet) that irreversibly binds to and inhibits platelet activation; because the lifespan of a platelet is 7-10 days, this is the average span of time needed after discontinuing anti-platelet therapy with aspirin before its effects are no longer present and the chance of uncontrolled bleeding event is decreased

A nurse is caring for a client who is receiving vincristine to treat lung cancer. The nurse should monitor the client and recognize which manifestation as an indication that the client is experiencing an adverse effect of the drug?

weak hands grasps this drug can cause peripheral neuropathy; nurse should monitor deep-tendon reflexes and the strength and movement of the hands and feet; nurse should tell the client to report paresthesias or reduced sensation in the hands or feet