WileyPlus Chapter 6

Which two minerals are stored in major quantities in bone tissue? A. calcium and phosphorus B. calcium and iron C. iron and phosphorus D. calcium and iodine E. calcium and sodium

A. calcium and phosphorus

How are osteons in compact bone tissue aligned? How does the osteon arrangement affect bone strength? A. horizontal to the metaphysis; the epiphyseal plate resists tearing due to the arrangement of osteons. B. parallel to the epiphysis; the spongy bone follows the alignment of the osteons increasing the strength of the bone ends. C. parallel to the length of the diaphysis; the shaft resists bending even when stresses are applied in certain directions. D. randomly between the epiphyseal plates; the random arrangement of osteons makes the shaft strong no matter what direction the bone is stressed. E. parallel to the perforating canals; the osteons running adjacent to the canals protects the vessels and nerves from becoming damaged.

C. parallel to the length of the diaphysis; the shaft resists bending even when stresses are applied in certain directions.

Hematopoiesis takes place in the ________ of some adult bones. A. Yellow bone marrow B. Canaliculi C.Red bone marrow D. Osteons E. Periosteum

C.Red bone marrow

During a needle biopsy of a person's bone marrow, maybe to test for the presence of cancer, pain is felt when the needle passes through the periosteum because it is richly supplied with nerves. True False

True

Bone can be classified as a connective tissue because it contains an extracellular matrix that surrounds widely spaced cells. True False

True

Bone remodeling, especially bone resorption, plays a role in the maintenance of proper levels of calcium in the blood. True False

True

Calcitonin inhibits activity of osteoclasts, speeds blood calcium uptake by bone, and accelerates calcium deposition into bones. True False

True

_______ contribute(s) to the hardness of bone while ________ give(s) it flexibility. A. Mineral salts; collagen and other organics B. Collagen; mineral salts C. Proteins; hydroxyapatite D. Yellow bone marrow; collagen

A. Mineral salts; collagen and other organics

Gravity and the pull of muscles against bone are the main mechanical stresses experienced by bone. Stress promotes deposition of mineral salts, collagen, and the strengthening of bone in stressed areas. Which of the following individuals would have a lower rate of bone deposition and would therefore be at greater risk for bone loss through bone resorption? A. a secretary who works at a desk job and does not do any regular weight-bearing exercise B. a college student who plays racket ball and jogs several days per week C. a construction worker who goes up and down ladder carrying tools and building materials all day D. a retired teacher who does all of her own yard work and who hikes with friends and family on the weekends E. none of these individuals are at any significant risk for loss of bone mass

A. a secretary who works at a desk job and does not do any regular weight-bearing exercise

By which process, as an individual grows to adulthood, is the thickness (diameter) of bone increased? A. appositional growth B. primary ossification C. secondary ossification D. chondrocyte calcification E. all of these processes occur

A. appositional growth

The process of intramembranous ossification generates bone within a pre-existing template composed of mesenchymal tissue. In contrast, endochondral ossification generates bone within a pre-existing template composed of _____. A. hyaline cartilage B. periosteum C. articular cartilage D. adipose tissue E. none of these choices

A. hyaline cartilage

Compact bone is composed of units called osteons. In contrast, spongy bone is composed of _____. A. trabeculae B. cartilage C. periosteum D. yellow bone marrow E. lacunae

A. trabeculae

Which of the following regions of bone would not undergo bone remodeling as frequently as the other regions? A. spongy bone B. compact bone C. bone subjected to new stresses damaged bone D. all of these have similar rates of remodeling

B. compact bone

Cells active when cartilage needs to be removed so new bone can be produced. A. osteoprogenitor cells B. osteoclasts C. osteocytes D. osteoblasts E. chondroblasts

B. osteoclasts

With aging, bones can become more brittle. This brittleness is due to which factor? A. a greater rate of bone resorption results in loss of calcium salts from the bone matrix B. with aging, there is a reduction in collagen synthesis by osteoblasts, which means a loss of tensile strength C. a loss of the ability of bone cells to synthesize vitamin C needed for collagen synthesis D. most elderly people are deficient in vitamins A and D, and also in calcium E. for women and men, the complete loss of estrogen means that all older individuals will develop osteoporosis

B. with aging, there is a reduction in collagen synthesis by osteoblasts, which means a loss of tensile strength

Which of the following is mismatched? A. Zone of resting cartilage - anchors the epiphyseal plate to the epiphysis. B. Zone of proliferating cartilage - Large chondrocytes arranged in stacks divide to replace those dying at the diaphyseal side of the epiphyseal plate. C. Zone of hypertrophic cartilage - consists of rapidly dividing immature chondrocytes D. Zone of calcified cartilage - is converted into bone by endochondral ossification. E. Epiphyseal line - signifies the end of longitudinal bone growth

C. Zone of hypertrophic cartilage - consists of rapidly dividing immature chondrocytes

An elderly woman trips and falls. She puts out her hand to try to stop her fall, and ends up with a fracture of the lower arm. An x-ray shows that at the break, many pieces of bone have a splintered and fragmented appearance. Which type of fracture does this woman have? A. open (compound) fracture B. closed fracture C. comminuted fracture D. greenstick fracture E. stress fracture

C. comminuted fracture

Most of the bones of the skull are formed by this process. A. interstitial growth B. growth at the epiphyseal plate C. intramembranous ossification D. endochondral ossification E. appositional growth

C. intramembranous ossification

Once osteoblasts have surrounded themselves with the extracellular matrix of bone tissue, they remain inside little chambers called __________ where they carry on the metabolic functions that maintain bone tissue. At this point, the cells are called osteocytes. A. endosteum B. trabeculae C. lacunae D. periosteum E. osteons

C. lacunae

In which region of a long bone, such as the humerus, would you find the epiphyseal plate (growth plate)? A. epiphysis B. diaphysis C. metaphysis D. periosteum E. endosteum

C. metaphysis

Which of the following is incorrectly matched? A. Diaphysis - shaft of bone B. Epiphysis - proximal and distal ends of the bone C. Epiphyseal growth plate - found in metaphysis of a growing bone D. Articular cartilage - composed of elastic cartilage to allow flexibility E. Endosteum - lines the medullary cavity

D. Articular cartilage - composed of elastic cartilage to allow flexibility

Which of the following is mismatched? A. Osteogenic cells - give rise to osteoblasts B. Osteoblasts - secrete matrix material C. Osteocytes - maintain bone tissue D. Osteoclasts -are derived from osteoblasts and break down bone tissue

D. Osteoclasts -are derived from osteoblasts and break down bone tissue

List the order of the zones in an epiphyseal plate from the diaphyseal region to the distal epiphysis. A: Zone of calcified cartilage B: Zone of hypertrophic cartilage C: Zone of proliferating cartilage D: Zone of resting cartilage A. a,c,d,b B. b,a,c,d C. a,b,d,c D. a,b,c,d

D. a,b,c,d

Which of the following factors affect bone remodeling and growth? A. minerals B. vitamins C. hormones D. all of these choices

D. all of these choices

The ______ is composed of hyaline cartilage and reduces friction between bones involved in a joint. A. periosteum B. distal epiphysis C. epiphyseal line D. articular cartilage E. epiphyseal plate

D. articular cartilage

The cells active in fracture repair during the production of the hard (spongy bone) callus. A. fibroblasts B. osteoclasts C. osteocytes D. osteoblasts E. chondroblasts

D. osteoblasts

Which is formed from the fusion of as many as 50 monocytes (a type of white blood cell)? A. osteogenic cell B. osteoblast C. osteocyte D. osteoclast

D. osteoclast

Which represents the correct sequence of development of bone cells? A. osteoprogenitor cells → osteocytes → osteoblasts → osteoclasts B. osteoblasts → osteoclasts → osteoprogenitor cells → osteocytes C. osteoclasts → osteoblasts → osteocytes → osteoprogenitor cells D. osteoprogenitor cells → osteoblasts → osteocytes E. osteoprogenitor cells → osteoblasts → osteocytes → osteoclasts

D. osteoprogenitor cells → osteoblasts → osteocytes

Bone mass reduction is promoted by which hormone? A. calcitriol B. calcitonin C. human growth hormone D. parathyroid hormone E. insulin

D. parathyroid hormone

Which is the proper sequence of steps in the healing of a fracture (the steps are listed below but are not in the correct sequence of events): 1 osteoblasts form trabecular bone that joins together the fractured ends of the bone and bony callus replaces fibrocartilage callus 2 bone remodeling occurs and compact bone replaces the spongy bone around the periphery of the fracture site 3 fibroblasts and chondrocytes from the periosteum form the fibrocartilage callus 4 a fracture hematoma forms and bone cells in the region of the fracture die 5 phagocytes and osteoclasts begin to remove the dead cells and damaged tissue around the hematoma A. 4, 5, 1, 2, 3 B. 5, 4, 3, 1, 2 C. 4, 5, 2, 3, 1 D. 3, 1, 2, 4, 5 E. 4, 5, 3, 1, 2

E. 4, 5, 3, 1, 2

Which of the following tissues could be found on or within a bone, such as the humerus? A. adipose tissue B. nervous tissue C. cartilage D. osseous tissue E. all of these

E. all of these

Which is not a function of the skeletal system? A. assistance in movement B. support C. protection D. mineral homeostasis E. carbohydrate storage

E. carbohydrate storage

Bone tissue stores 99% of the body's calcium. Calcium plays important roles beyond the mineralization of bones. The exchange of calcium between bone and body fluids (especially the blood) is regulated by several hormones. Which of the following is the most important hormone regulating calcium exchange? A. vitamin D (calcitriol) B. calcitonin C. thyroid hormones (T3 and T4) D. human growth hormone (hGH) E. parathyroid hormone (PTH)

E. parathyroid hormone (PTH)

A greenstick fracture would only be seen in an elderly person with more fragile bones. True False

False

As long bones form in the fetus, the formation of the medullary cavity occurs because of the actions of osteoblast cells. True False

False

During the process of bone formation in a fetus, a primary ossification center develops in the epiphysis of a cartilage model of a long bone. True False

False

Ikea is a ten year old child raised on the planet Beneckea which has half the gravity of earth. Her parents have decided to move their family back to earth. Will Ikea need to increase or decrease her bone mass to live comfortably on earth? Increase Decrease

Increase