A&P Lab 10 HW
How does the myosin head obtain the energy required for activation?
The energy comes from the hydrolysis of ATP
What is name given to the regularly spaced infoldings of the sarcolemma?
transverse or t tubules
The cross bridge cycle is a series of molecular events that occur after excitation of the sarcolemma. What is a cross bridge?
A myosin head bound to actin
A triad is composed of a T-tubule and two adjacent terminal cisternae of the sarcoplasmic reticulum. How are these components connected?
A series of proteins that control calcium release.
After a power stroke, the myosin head must detach from actin before another power stroke can occur. What causes cross bridge detachment?
ATP binds to myosin head
Action potential propagation in a skeletal muscle fiber ceases when acetylcholine is removed from the synaptic cleft. Which of the following mechanisms ensures a rapid and efficient removal of acetylcholine?
Acetylcholine is degraded by acetylcholinesterase.
The neuromuscular junction is a well-studied example of a chemical synapse. Which of the following statements describes a critical event that occurs at the neuromuscular junction?
Acetylcholine is released by axon terminals of the motor neuron.
Calcium ions couple excitation of a skeletal muscle fiber to contraction of the fiber. Where are calcium ions stored within the fiber?
Calcium ions are stored in the sarcoplasmic reticulum.
What specific event triggers the uncovering of the myosin binding site on actin?
Calcium ions bind to troponin and change its shape.
Excitation of the sarcolemma is coupled or linked to the contraction of a skeletal muscle fiber. What specific event initiates the contraction?
Calcium release from the sarcoplasmic reticulum initiates the contraction.
When does cross bridge cycling end?
Cross bridge cycling ends when sufficient calcium has been actively transported back into the sarcoplasmic reticulum to allow calcium to unbind from troponin.
Excitation-contraction coupling is a series of events that occur after the events of the neuromuscular junction have transpired. The term excitation refers to which step in the process?
Excitation, in this case, refers to the propagation of action potentials along the sarcolemma.
Calcium entry into the axon terminal triggers which of the following events?
Synaptic vesicles fuse to the plasma membrane of the axon terminal and release acetylcholine.
What is the relationship between the number of motor neurons recruited and the number of skeletal muscle fibers innervated?
Typically, hundreds of skeletal muscle fibers are innervated by a single motor neuron.
Which of the following is most directly responsible for the coupling of excitation to contraction of skeletal muscle fibers?
calcium ions
Action potentials travel the length of the axons of motor neurons to the axon terminals. These motor neurons __________.
extend from the brain or spinal cord to the sarcolemma of a skeletal muscle fiber
Acetylcholine binds to its receptor in the sarcolemma and triggers __________.
the opening of ligand-gated cation channels
What structure is the functional unit of contraction in a skeletal muscle fiber?
the sarcomere
