Alonzo Exam 4 Review

According to DSM-5 criteria for diagnosing someone with substance use disorder, which of the following are incorrect? A. Tolerance and dependence always lead to substance use disorder B. In the clinical course of substance use disorder the binge/intoxication phase is irreversible C. Substance use disorder is not typically defined or assessed by severity

All are incorrect: A. Tolerance and dependence always lead to substance use disorder -Tolerance and dependence DO NOT always lead to substance use disorder B. In the clinical course of substance use disorder the binge/intoxication phase is irreversible -the binge/intoxication phase is REVERSIBLE C. Substance use disorder is not typically defined or assessed by severity -Substance use disorder can be defined or assessed by severity using the Addiction Severity Index *be able to identify the correct option not given

Which of the following statements regarding clinical long term effects of alcohol use are true? A. Long term alcohol use can cause capillary hemorrhage. B. Long term alcohol use is associated with bone marrow suppression. C. Long term alcohol use is associated with peripheral neuropathy. D. Long term alcohol use is associated with erectile dysfunction

All are true: A. Long term alcohol use can cause capillary hemorrhage. B. Long term alcohol use is associated with bone marrow suppression. C. Long term alcohol use is associated with peripheral neuropathy. D. Long term alcohol use is associated with erectile dysfunction

With regards to the typical presentation and clinical course of substance use disorder, all are true except A. Remission and relapses are the rule just like any other disease state B. 100% of people affected by substance use disorder are eventually able to abstain from substance use

B. 100% of people affected by substance use disorder are eventually able to abstain from substance use -Not true -Remission and relapses are the rule just like any other disease state, this is true

Which of the following risk factors are true for patients diagnosed with opioid use disorder? A. Psychotic delusions and hallucinations and increased risk of ADHD B. Hepatitis B, HIV, endocarditis, tuberculosis, and pneumonia infections C. Mortality estimated to be 13x higher than non-drug users D. Medication assisted treatment increases risk of overdose

B. Hepatitis B, HIV, endocarditis, tuberculosis, and pneumonia infections C. Mortality estimated to be 13x higher than non-drug users -psychotic delusions and hallucinations and increase risk of ADHD - FALSE -medication assisted treatment DOES NOT increase risk of overdose

Which of the following regarding substance use disorder are true? A. Binge/Intoxication phase is irreversible B. In Withdrawal/Negative Effect Phase, with frequent use neuroadaptations occur followed by withdrawal symptoms, especially with alcohol or opioids C. In Preoccupation/Anticipation Phase the cycle of drug use is established due to longer-term need for drug use

B. In Withdrawal/Negative Effect Phase, with frequent use neuroadaptations occur followed by withdrawal symptoms, especially with alcohol or opioids C. In Preoccupation/Anticipation Phase the cycle of drug use is established due to longer-term need for drug use - Binge/intoxication phase is REVERSIBLE

Regarding naltrexone which of the following are true? A. Naltrexone is a partial agonist and has misuse potential. Naltrexone is a DEA controlled substance CIII and may be appropriate for patients with a less severe form of the disorder B. It is necessary for a patient to completely withdrawal from opioids prior to initiating therapy with naltrexone. Naltrexone will precipitate opioid withdrawal if the patient has not completed the detoxification C. 50% of patients who are initiated on naltrexone will test the blockade

B. It is necessary for a patient to completely withdrawal from opioids prior to initiating therapy with naltrexone. Naltrexone will precipitate opioid withdrawal if the patient has not completed the detoxification C. 50% of patients who are initiated on naltrexone will test the blockade - False, Naltrexone is not a partial agonist, no misuse potential, not a controlled substance

Regarding buprenorphine, which of the following are true? A. Buprenorphine is a full opioid agonist that's dosage forms include short acting syrup, lozenge, and a long-acting injectable B. Warning or precautions associated with buprenorphine include cardiovascular and respiratory depression and the potential of misuse C. Buprenorphine is associated with opioid craving reduction and can be combined with naloxone to prevent misuse D. Recommended target dose of buprenorphine is 16 mg/day.

B. Warning or precautions associated with buprenorphine include cardiovascular and respiratory depression and the potential of misuse C. Buprenorphine is associated with opioid craving reduction and can be combined with naloxone to prevent misuse D. Recommended target dose of buprenorphine is 16 mg/day. -Buprenorphine is a partial opioid agonist that's dosage forms include daily oral tabs, films, and sublingual tablets, long-acting implant, and long-acting injectable

Which of the following is not true about short-term clinical effects of EtOH? A. Interacts with neuroreceptors GABA, DA, 5HT, and glutamate B. Large amounts impact motor impairment, decision-making, and judgement C. Enters the blood stream quickly and metabolized by the liver at 1000oz per hour with 100 proof alcohol

C. Enters the blood stream quickly and metabolized by the liver at 1000oz per hour with 100 proof alcohol -This is not true True: -Interacts with neuroreceptors GABA, DA, 5HT, and glutamate -Large amounts impact motor impairment, decision-making, and judgement

Which of the following is a sign or symptom of opioid overdose? A. Rapid heartbeat (tachycardia) B. Extremely agitated behavior C. Respiratory depression D. Unresponsiveness

C. Respiratory depression D. Unresponsiveness Rapid heartbeat (tachycardia) and Extremely agitated behavior are not signs or symptoms

Which drug is matched with the correct use? A. Abilify and psychotic paranoid delusions B. Carbamazepine and agitation C. Thiamine supplementation and Wernicke's/Kosakoff syndrome D. Chlordizepoxide and Nausea/Vomiting

C. Thiamine supplementation and Wernicke's/Kosakoff syndrome

All of the following are considered risk factors for substance use disorder except A. Genetic polymorphism B. Psychiatric comorbidities C. Stressful environment D. Exposure to substances much later in life

D. Exposure to substances much later in life -not a risk factor

Regarding methadone, which of the following statements are true? A. Methadone is one of the 3 FDA approved medications to treat opioid use disorder which include methadone, buprenorphine and naloxone B. Methadone is a long acting partial opioid agonist that is associated with decreased cravings, decreased euphoria, and prevention of withdrawal symptoms C. Methadone is a controlled substance DEA Schedule III that can be prescribed by a physician for use in opioid use disorder if the physician has obtained a DEA X waiver D. Methadone is provided to patients under medical supervision after federally qualified opioid treatment programs with in addition to medication provide comprehensive individually tailored therapy

D. Methadone is provided to patients under medical supervision after federally qualified opioid treatment programs with in addition to medication provide comprehensive individually tailored therapy -Methadone is one of the 3 FDA approved medications to treat opioid use disorder which include methadone, buprenorphine and NALTREXONE -Methadone is a controlled substance DEA Schedule ONE that can be prescribed by a physician for use in opioid use disorder if the physician has obtained a DEA X waiver -Methadone is a slow acting FULL opioid mu-receptor agonist that is associated with decreased cravings, decreased euphoria, and prevention of withdrawal symptoms

Which of the following medications has an FDA indication for both alcohol use disorder and opioid use disorder? A. diacetylmorphine B. naloxone C. aplenalone D. naltrexone

D. Naltrexone

Which of the following medications is paired with the correct symptom it is trying to address relative to alcohol withdrawal treatment? A. lorazepam and korsakoff syndrome B. Thiamine supplementation and seizures C. olanzapine with sedation D. ondansetron with nausea and vomiting

D. Ondansetron and Nausea and vomiting

What is an important counseling point when dispensing metronidazole?

Nausea, vomiting, and sickness can occur in use of mouthwash