Bio Ch. 8 and 9 Quiz
The term metastasis refers to the fact that cancer cells tend to
Spread
If a solid tumor is discovered at an early stage, which treatment method is most often used?
Surgery
When a portion of a chromosome breaks off and attaches to a different chromosome, this is called a(n)
Translocation
Cytokinesis usually, but not always, follows mitosis. If a cell undergoes mitosis and not cytokinesis, this would result in
a cell with two nuclei.
The term tetrad refers to
two homologous chromosomes each comprised of two sister chromatids.
Losing weight can reduce an obese person's risk for cancer by up to
40%.
If a cell has 46 chromosomes at the beginning of mitosis, then at the end of anaphase there would be a total of
92 chromosomes.
During meiosis II,
chromosomes aligned separately at the metaphase plate, and each sister chromatid facing the opposite spindle pole.
In an experiment, cells grown in a petri dish divided until they formed a thin single layer. When cells were removed from the middle of the dish, the cells bordering the open space began dividing until they had filled the empty space. This type of regulation is called
contact inhibition.
What structure is formed by two sister chromatids being held together by a centromere?
duplicated chromosome
When during the cell cycle are chromosomes visible under a microscope?
during M phase
If you were looking under the compound light microscope at an onion root tip, in what stage of the cell cycle would the majority of the cells be?
interphase
If tumor cells have a faulty, non-functional proteinase, they will be unable to undergo which of the following processes?
metastasis
The mitotic spindle is composed of________, which originate from the________.
microtubules; centrosome
The failure of sister chromatids to separate during meiosis is called
nondisjunction.
Cells that do not receive the correct signals to move from G1 into S phase will enter G0 and therefore will
not undergo mitotic division unless it later receives the go-ahead signal.
Chromatin wrapped around histones form a bead-like structure known as a
nucleosome.
Which of the following is a function only of mitosis?
organismal growth
Which of the following only occurs once during meiosis?
pairing of homologous chromosomes
Anushka was examining a cell under the microscope and she noticed the formation of a cell plate in the midline of the cell and the formation of nuclei at opposite poles of the cell. The cell under examination was most likely a(n)
plant cell undergoing cytokinesis.
Plant cells and animal cells differ in cytokinesis because
plant cells need to build a cell wall, while animal cells do not.
All of the following results from nondisjunction except
polyploidy.
Some of the drugs used in chemotherapy work by
preventing spindle formation
Unicellular organisms undergo mitotic division to
produce new organisms.
Telomeres function to
promote chromosomal stability.
Which of the following occurs prior to prophase?
synthesis of DNA
Denzel was looking at onion root tip cells under the microscope in biology class. He saw one cell that had two nuclei within it. What stage of the cell cycle was this cell in?
telophase
During which stage of the cell cycle does the spindle disappear?
telophase
An individual with the karyotype 48, XYYY would have how many Barr bodies?
0
In each gamete following telophase II, how many copies of each gene is/are present?
1
Female vampyressine bats have a diploid (2n) chromosome number of 22. At prophase I, each cell would have________ homologous pairs present, for a total of________ chromatids.
11;44
Cheetahs have a diploid chromosome number of 38. At prophase I, a cheetah's cell would have how many homologous pairs?
19 pairs of chromosomes
During the G1 stage of interphase, a diploid organism contains how many copies of each gene?
2
The failure of sister chromatids to separate in one of the cells during meiosis II would result in how many normal gametes?
2
A group of cells is assayed for DNA content immediately following mitosis and is found to have an average of 10 picograms of DNA in the nucleus during G1. Those cells would have________ picograms at the end of the S phase and________ picograms at the end of G2.
20; 20
Female vampyressine bats have a diploid (2n) chromosome number of 22. At prophase II, each cell would contain how many chromatids?
22
Which pair of chromosomes on a karyotype would show you the sex of a baby?
23rd pair
If there are 20 centromeres in a cell, how many sister chromatids are there?
40
Which of the following does NOT describe a cancer cell?
A cell regulated by contact inhibition
You are looking at a cell under a microscope and see what appears to be several "X" structures being pulled to each side of the cell. What stage of meiosis are you looking at?
Anaphase I
Since homologous chromosomes are separating, the cell shown in the diagram is what meiotic phase Since the cell has not split into two daughter cells yet, the cell is still what?
Anaphase I (2n)
Cells grown in a petri dish tend to divide until they form a thin layer covering the bottom of the dish. Which of the following statements explains why this occurs?
Cell division can be inhibited by the proximity of other cells.
What is the structure that holds together the two sister chromatids that form a chromosome?
Centromere
What structure holds two sister chromatids together?
Centromere
Which cancer therapy can lead to side effects such as nausea and hair loss?
Chemotherapy
Which of the following is an inaccurate statement about crossing-over?
Crossing-over occurs between sister chromatids.
If a cell is inhibited during the S phase of its cycle, it will not reproduce due to lack of
DNA synthesis.
Differentiated cells, such as nerve cells, would be in which of the following stages of the cell cycle?
G0
Which of the following is mismatched?
G2 stage - mitosis begins
Which of the following organelles would be abundant and in close proximity to the cell plate in a plant cell undergoing cytokinesis?
Golgi Apparatus
The presence of which protein is required in order for chromatin to compact correctly within the nucleus?
Histone
What is the face with the nucleus and nucleolus are intact., the DNA is in the form of chromatin and is not visible under the microscope.
Interphase
Which of the following statements is correct regarding the events of the cell cycle?
Interphase consists of G1, S, and G2.
Pevita has a tumor in her ovaries. She recently underwent a series of tests and is returning to the doctor to find out the results. Which of the following would be the best news that Pevitacould receive from her doctor?
It is a benign tumor.
Nuclear division occurs during
M phase
The drug chloral hydrate prevents elongation of microtubules. During which stage of the cell cycle would chloral hydrate be most harmful?
M phase
Which of the following statements is true?
Meiosis involves two divisions and produces four nonidentical gametes.
Chromosomes line up at the spindle equator of the cell during what mitotic phase?
Metaphase
Homologous chromosomes are aligned together at the metaphase plate. the homologous chromosomes have not yet been separated into two new daughter cells,
Metaphase I (2n)
Swyer syndrome (46, XY, female appearance), would most likely result from
Normal disjunction during meiosis, but deletion of a portion of the Y chromosome in the male parent.
A cell has early mitotic spindles, centrosomes, breaking nuclear envelope, and chromosomes consisting of two sister chromatids. What mitotic stage is it in?
Prophase
There are no longer any homologous pairs (characteristic of meiosis II) and the chromosomes, which each still consist of two sister chromatids, are not yet aligned at the metaphase plate.
Prophase II (n)
Which of the following represents the phases of mitosis in their proper sequence?
Prophase, metaphase, anaphase, and telophase
Inheritance of mutant forms of some genes may lead to a predisposition to develop cancer. Which of the genes listed below takes its name from its association with an eye tumor?
RB
Cancer is a disorder in which some cells have lost the ability to control their
Rate of cell division
Which of the following pairs is correctly matched?
S phase - DNA replication
A tumor suppressor gene undergoes a mutation that causes it to lose its normal function. What would be the most likely result of this mutation?
The cell no longer responds to signals that cause it to stop dividing or undergo apoptosis.
Which of the following is an inaccurate statement about mitosis?
The cells arising from mitosis contain only half of the necessary genetic material.
How do the daughter cells at the end of mitosis and cytokinesis compare to their parent cell when it was in G1 of the cell cycle?
The daughter cells have the same number of chromosomes and the same amount of DNA.
Why might a cell be prevented from proceeding through the G1 checkpoint?
There is DNA damage.
A human egg with 22 chromosomes that is fertilized by a normal sperm will result in
a zygote with monosomy
The human life cycle consists of
adults who are diploid and produce haploid gametes, these gametes fuse to produce a diploid zygote which grows into an adult.
An individual with Swyer syndrome (46, XY) differs from an individual with Klinefelter syndrome (47, XXY) because
an individual with Klinefelter syndrome has a functional SRY gene on his Y chromosome, whereas an individual with Swyer syndrome does not.
An oncogene is more likely to lead to cancer than a proto-oncogene because
an oncogene is more likely to accelerate the cell cycle.
During which phase of mitosis are the sister chromatids separated and consequently become daughter chromosomes?
anaphase
Which of the following phase(s) separates sister chromatids into daughter chromosomes?
anaphase II and anaphase of mitosis
Which of the following would increase your risk of cancer?
avoiding a high-fiber, low-sodium diet
Telomerase normally functions in
both embryonic and adult stem cells
Apoptosis
can be used to remove damaged or malfunctioning cells.
Translocations
can lead to cancer if they disrupt the genes that regulate the cell cycle.
An enzyme that promotes apoptosis is generally known as a(n)
caspase
Following meiosis I, the daughter cells are________; following meiosis II, the daughter cells are________; and following fertilization the daughter cells are________.
diploid; haploid; diploid
A translocation may lead to cancer if it
disrupts control of expression of genes that regulate the cell cycle.
A mutation that causes an increase in function in a tumor suppressor gene would not likely cause cancer because a tumor suppressor protein
does not promote cell division.
During crossing-over,
genetic material is exchanged between nonsister chromatids, resulting in new combinations of alleles.
Metaphase II is more similar to metaphase of mitosis than to metaphase I because
in metaphase II, chromosomes align separately at the spindle equator.
Multicellular organisms undergo mitotic cell division to
increase the size of the organism.
All of the following are characteristics of someone with Down syndrome except
increased muscular strength.
Which of the following is a correct match?
separation of sister chromatids - anaphase II
A centromere holds together two
sister chromatids
Which lifestyle choice is responsible for 90% of the cases of lung cancer among men?
smoking
A proto-oncogene differs from a tumor suppressor gene because a proto-oncogene
stimulates cell division in a normal cell, whereas a tumor suppressor gene inhibits cell division.
Proto-oncogenes function by
stimulating the cell cycle when appropriate signals and growth factors are present.
The G2 checkpoint prevents the cell cycle from continuing until
the DNA has finished replicating.
Cytokinesis in plants occurs as________ and in animals as________.
the Golgi apparatus produces membrane-bound vesicles filled with materials to make the cell wall; actin fibers pull the membrane inward until the two sides touch
A positive genetic test for telomerase in an adult somatic body cell, such as a fibroblast, may indicate that
the cell is cancerous.
A mutation results in a cell that no longer produces a normal protein needed for the M-phase checkpoint. Which of the following would likely be the immediate result of this mutation?
the cell would never leave metaphase
If the production of cyclins halted during the cell cycle
the cell would not proceed to the next phase of the cell cycle.
Which of the following is a characteristic of cancer cells?
the nucleus is abnormally shaped.
Cancer occurs when
the regulation of the cell cycle is lost and uncontrolled cell division occurs.
