BOC Images

B = Fc fragment A = Fab fragment

Match terms with fragments resulting from papain digestion of an IgG molecule:

HbSS

The hemoglobin electrophoresis patterns that are shown on the right include controls for A, S, and C; and A and F above and below the patient results. The patient lanes displayed in these hemoglobin electrophoresis patterns are consistent with what diagnosis? HbSA HbSD HbSS HbS/HPFH

Entamoeba coli cysts are easily recognizable due to their size (around 30 µm), number of nuclei (the only cyst with up to 8), and nuclear characteristics - uneven peripheral chromatin and eccentric karyosomes.

This suspicious form, recovered from a stool sample, measures 30 µm in diameter. Entamoeba hartmanni cyst Entamoeba coli cyst Entamoeba histolytica cyst Pseudoparasite

Diphyllobothrium latum has a relatively complex life cycle outside of humans that involves copepods and fish. Measures designed to halt the spread of broad fish tapeworm infection include thorough cooking of all fish prior to consumption and the avoidance of using human feces as fertilizer. If these measures could be universally practiced, the parasite would probably cease to cause human infections.

A 54 year old Finnish male presented at the local clinic with abdominal pain, weight loss, overall weakness and digestive discomfort. Patient history revealed that the man's diet was rich in raw fish. A complete blood count (CBC) was performed and revealed macrocytic anemia. A stool for parasitic examination was ordered. This suspicious form was seen upon initial screening of the sample. It measures 77 µm by 48 µm. This patient is most likely suffering from an infection with: Clonorchis sinensis Paragonimus westermani Fasciolopsis buski Diphyllobothrium latum

Chagas' Disease: The hemoflagellate morphologic form shown is that of the trypomastigote. It may be identified on the basis of shape, position of the nucleus, and the presence of a full-body length undulating membrane that culminates into a single flagellum. This patient is exhibiting the classic symptoms and morphologic form of Chagas' disease caused by Trypanosoma cruzi trypomastigotes.

A 68-year-old female, who recently vacationed in Brazil, presented to her physician exhibiting overall weakness, fever, and enlarged lymph nodes. Blood was collected for culture and parasitic examination. The culture was negative. This suspicious form was recovered upon examining the Giemsa-stained preparation. This patient is most likely suffering from: Chagas' disease East African sleeping sickness West African sleeping sickness None; considered non-pathogenic

B) Test newborn's plasma against group A1 red cells and group O antibody screen cells by IAT.

A mother's serologic results are shown above. Her newborn types as group A Rh positive with a (1+) positive direct antiglobulin test (DAT). Which of the following investigative tests would be most useful to resolve the cause of the positive DAT and should be done FIRST? A) Test an eluate prepared from newborn's red cells against an antibody identification panel by IAT. B) Test newborn's plasma against group A1 red cells and group O antibody screen cells by IAT. C) Test newborn's plasma against mother's red cells by IAT. D) Test newborn's plasma against father's red cells by IAT.

Lymphocytosis -Lymphocytosis is a condition in which there is an increase in the lymphocyte population. In most laboratories, lymphocytosis is defined as lymphocyte counts greater than 40%, depending on the patient age.

An increase in the predominant white cell type in this illustration is indicative of: Thrombocytopenia Monocytosis Leukopenia Lymphocytosis

Pappenheimer bodies (iron containing bodies!)

By utilizing a Prussian Blue stain, which of the following red blood cell inclusions would be identifiable if present?

Calcium oxalate crystals

Identify the urine sediment elements indicated by the arrows in this microscopic field. Calcium oxalate crystals Uric acid crystals Amorphous urate crystals Cystine crystals

WBC casts (leukocyte casts) usually indicate pyelonephritis.

Identify the urine sediment elements shown by the arrow: WBC casts RBC casts Waxy casts Granular casts

B) The cell type increased in the peripheral blood smear in immediate hypersensitivity reactions is the basophil. Increases in peripheral smear basophils may also be associated with prominent mast cells as seen in tissue sections in hypersensitivity syndromes. Frame A contains an eosinophil, associated with many conditions such as drug reactions and parasitic infections, particularily invasive parasites as Toxacara canis and Trichinella. Allergies such as hayfever, asthma, and urticaria may be associated with eosinophilia. The cell in Frame C containing Chediak-Higashi inclusions and the phagocytized bacteria in Frame D are not related to hypersensitivity conditions.

Select the letter representing the cell that can be seen in increased concentrations in the peripheral blood smear during immediate hypersensitivity reactions:

Stomatocytes

What are the cells that are indicated by the arrows in this slide? Keratocytes Stomatocytes Drepanocytes Prekeratocytes

Howell-Jolly bodies

What is the identification of the red blood cell inclusions indicated by the arrows on this peripheral blood smear image? Howell-Jolly bodies Pappenheimer bodies Heinz bodies Basophilic stippling