CBIO 2210 | Q1: Blood 2

Leukopoiesis involves the development of leukocytes along two lineages. The myelocytic lineage can lead to all of the following EXCEPT:

*A. T lymphocytes* B. monocytes C. erythrocytes D. neutrophils

The lifespan of circulating platelets is about:

A. 1 year B. 1 month C. 120 days *D. 10 days*

Which cells aid in the body's defense processes by secreting histamine and heparin?

A. Eosinophils *B. Basophils* C. Neutrophils D. Erythrocytes E. Platelets

What are the most abundant agranulocytes?

A. Monocytes B. Basophils *C. Lymphocytes* D. Eosinophils E. Neutrophils

Each of the following can reduce or inhibit clot formation EXCEPT:

A. aspirin. B. heparin. *C. ADP.* D. vitamin K deficiency. E. hypocalcemia.

If a certain drug blocks neutrophils from attaching to blood vessel walls and exiting the blood, it can be said that the drug blocks:

A. coagulation B. erythropoeisis *C. diapedesis* D. chemotaxis

Hemophilia is characterized by:

A. excessive fibrinogen production by the liver. B. inadequate production of heparin. C. thrombocytosis (excessive platelet count). *D. defective production of one (or more) of the clotting factors.*

Compared to the intrinsic pathway of coagulation, the extrinsic pathway is ____ and requires ____.

A. faster; platelets B. faster; vessel damage C. slower; calcium D. slower; platelet activation *E. faster; thromboplastin*

Leukopenia:

A. is defined as a WBC count > 11,000/microliter. *B. can be caused by chronic stress.* C. is usually a side-effect of a bacterial infection. D. is classified as lymphocytic or myelocytic.

In the coagulation cascade, the common pathway begins when:

A. platelets release calcium. B. damaged tissue cells release tissue factor (thromboplastin). C. platelets adhere to collagen that is exposed on damaged vessels. *D. prothrombin is converted to thrombin by factor Xa.*