Chapter 17 Endocrine System Lab

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How long can iodinated thyroglobulin be stored in a thyroid follicle lumen?

2-3 months

How many parathyroid glands are there?

2-6

The G-protein is composed of how many subunits?

3

What causes the change in conformation of the G-protein resulting in separation from the membrane bound receptor?

Ligand binding to the membrane bound receptor

Aldosterone is a...

Lipid-soluble hormone

The pancreas is...

Located between the duodenum and spleen, just inferior to the stomach

The hypothalamus is sometimes referred to as the "master control center" of the endocrine system because it...

Regulates most endocrine functions of the body

Parathyroid hormone promotes...

Resorption of calcium from bone

Which pancreatic islet cell type is correctly matched with its product?

beta cells: insulin

Which structure is highlighted?

body of pancreas

What cell in the parathyroid gland secretes parathyroid hormone?

chief (principal) cell

Which structure is highlighted?

chief cell of parathyroid gland

The cortex of the suprarenal (adrenal) glands produces...

corticosteroids

Which structure is highlighted?

infundibulum of pituitary

What is the name of the narrow band of tissue connecting the right and left lobes of the thyroid gland?

isthmus

The suprarenal (adrenal) glands are located superior to which organ(s)?

kidneys

Which structure is highlighted?

zona reticularis

In general, sensory input to a portion of the neuroendocrine system causes...

release hormones

Which structure is highlighted?

seminiferous tubules

Below are 6 histology slides of endocrine glands. Place the appropriate hormones in the glands they are secreted from.

1. posterior pituitary: oxytocin, ADH 2. pancreas: insulin, glucagon 3. anterior pituitary: growth hormone, FSH 4. adrenal cortex: aldosterone, cortisol 5. thyroid gland: thyroxine, calcitonin 6. parathyroid gland: PTH

The hypothalamo-hypophyseal portal system connects the hypothalamus to the...

Adenohypophysis

In the cytoplasm of a cell, aldosterone...

Binds to an intracellular aldosterone receptor

The pancreatic acinar cells secrete...

Enzyme-rich pancreatic juice

The medulla of the suprarenal gland secretes _____________ to enhance the ______________ response of the sympathetic nervous system.

Epinephrine & norepinephrine; "fight or flight"

What activates the alpha subunit of the G-protein?

GTP replacing GDP

As an example of hormonal communication, when osmoreceptors of the _______________ detect dehydration, a signal to the posterior pituitary gland causes the release of _________________.

Hypothalamus: Antidiuretic hormone (ADH)

Antidiuretic hormone (known as ADH or vasopressin)...

Increases water retention from renal tubules

The endocrine portion of the pancreas produces...

Insulin and glucagon

Ultimately, what is responsible for aldosterone's effects on a cell?

Intracellular proteins

What stimulates the secretion of parathyroid hormone from the parathyroid gland?

Low blood calcium level

The G-protein is found bound to the...

Membrane bound receptor on the inside of the cell

After aldosterone binds to an intracellular receptor, the receptor complex...

Moves into the nucleus and binds to DNA

Hormone molecules are typically transported to the target cells by...

The blood stream

What occurs when hormones reach their target cells?

The hormone binds to an appropriate receptor on (in) the target cell

What are the two main targets of antidiuretic hormone (ADH)?

The kidneys and blood vessels

What is the dominate amino acid in thyroglobulin?

Tyrosine

The principal mineralocorticoid is _____________ that helps regulate levels of _____________ in the blood and body fluids.

aldosterone; sodium and potassium ions

Which structure is highlighted?

follicular cell of thyroid

Which structure is highlighted?

follicular colloid of thyroid

Thyroid hormone stimulates the anterior pituitary to release...

growth hormone (GH)

Which structure is highlighted?

head of pancreas

The pituitary gland is located in the...

hypophyseal fossa

Which structure is highlighted?

hypothalamus

Which structure is highlighted?

ovary

Which structure is highlighted in yellow?

pancreas islet

Which structure is highlighted in yellow?

pancreatic acini

Which structure is highlighted?

parafollicular cell of thyroid

Which structure is highlighted?

pineal gland

Which structure is highlighted?

pituitary gland

The parathyroid glands are usually located on which surface of the thryoid gland?

posterior

Which structure is highlighted?

zona fasciculata

Which structure is highlighted?

suprarenal

Which structure is highlighted?

suprarenal cortex

Which structure is highlighted?

suprarenal medulla

Which structure is highlighted?

suspensory ligament of ovary

Which structure is highlighted?

tail of pancreas

Which structure is highlighted?

testes

Which structure is highlighted?

zona glomerulosa

Which structure is highlighted?

thyroid follicle

In the thyroid gland, where are iodide molecules converted to iodine?

thyroid follicle lumen

Which structure is highlighted?

thyroid gland

Which structure is highlighted?

thyroid isthmus

Which structure is highlighted?

tunica albuginea of testes


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