Chapter 18: Drug Therapy with Beta-Lactam Antibacterial Agents

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A client has been prescribed 500 mg of amoxicillin and potassium clavulanate acid (Augmentin) every 12 hours. The available drug is in the form of a 125-mg tablet. To meet the recommended dose, the nurse will administer _______ tablets each time.

4

A client is ordered to receive vancomycin IV. When administering the drug, the nurse would infuse the drug over which time frame?

60 minutes

Penicillin would NOT be indicated for which of the following clients?

A client with gram-negative bacteria allergic to penicillin

The nurse administers cefuroxime to a client at least 1 hour before meals, as prescribed; however, the client experiences GI upset. Which action would be most appropriate for the nurse to do?

Administer the drug with food.

A nurse suspects that a client receiving oral penicillin therapy is developing pseudomembranous colitis based on which assessment finding?

Bloody diarrhea

As a class, penicillins usually are more effective in infections caused by which type of bacteria?

Gram-positive

Penicillins are more effective when used on infections caused by what organism?

Gram-positive bacteria

The nurse is administering penicillin to a client who has strep throat. Which of the following statements accurately describe the action of penicillin? It is effective against gram-positive organisms

It is effective against gram-positive organisms

When discussing cephalosporins with the nursing class, the pharmacology instructor explains that this classification of drug is primarily excreted through which organ?

Kidney

A 75-year-old client with a history of renal impairment is admitted to the primary health care center with a UTI and has been prescribed a cephalosporin. Which intervention is most important for the nurse to perform when caring for this client?

Monitoring blood creatinine levels

The nurse is providing care to a client who is receiving an aminoglycoside and cephalosporin. Which assessment is a priority of care?

Nephrotoxicity

The nurse is preparing to administer nafcillin intravenously (IV) to a client. What is the most common reaction related to this method of administration?

Phelbitis

After teaching a group of nursing students about the action of penicillins, the instructor determines that the teaching was effective when the students identify natural penicillins as exerting which type of effect on microorganisms?

bactericidal

The health care provider is selecting an antibiotic for a client with a known penicillin allergy. The provider knows that cephalosporins are a poor choice for this client because cephalosporins:

can cause allergic reactions in clients who are allergic to penicillins.

A female client is admitted to the critical care unit with sepsis related to a contaminated central line. The health care provider orders intravenous beta-lactam antimicrobials. The client's current laboratory report reflects renal impairment. What would the nurse expect the provider to do?

decrease the drug does

A young adult client who has no significant prior health history has been prescribed antibiotics for the first time. What nursing diagnosis would be most appropriate for this client?

deficient knowledge regarding drug therapy

Cephalosporins are structurally and chemically related to which classes of antibiotics?

penicillin

The nurse has administered the first dose of a client's newly-prescribed antibiotic. What assessment finding should the nurse interpret as adverse effect that suggests a more serious concern?

rash to the face and trunk

A 7-year-old child has tonsillitis and is prescribed penicillin V, which is to be administered at home. The nurse will instruct the parents to administer the drug

with a glass of water 1 hour before or 2 hours after a meal.


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