Chapter 20 quiz
Which abx are used to treat fungal infections?
Aminoglycosides, cephalosporins, and griseofulvin
Erythromycin
Antimycoacterial antibiotic
ethambutol
Antimycobacterial antibiotic
Which of the following statements about drugs that competitively inhibit DNA polymerase or RNA polymerase is false?
They cause cellular plasmolysis
Mebendazole is used to treat cestode infections. It interferes with microtubule formation; therefore, it would NOT affect
bacteria
Most availible antimicrobial agents are effective against
bacteria
What is the method of action for Tamiflu?
competitive inhibition
Sulfanamides
competitive inhibitor of essential metabolite
Which of the following would be selective against the tubercle bacillus?
ethambutol-inhibits acid synthesis
Which compound would be the most useful to treat candidiasis?
flucytosine
A drug that inhibits mitosis, such as grisofulvin, would be more effective against
fungi
Niclosamide prevents ATP generation in mitochondria. You would expect this drug to be effective against
helminths
Amoxicillin
inhibitor to cell wall synthesis
Rifamycins
inhibitor to nucleic acid synthesis
Chlorophenicol
inhibitor to protein synthesis
Streptomycin
inhibitor to protein synthesis
Which ofthe following antimicrobial agents has the fewest side effects?
penicillin
Which antibiotic is recommended for use against gram-negative bacteria?
polymycin
Which of the following antibiotics is recommended against gram-negative bacteria?
polymyxin
More than 1/2 of our antibiotic are
produced by bacteria
Which of the following does NOT affect eukaryotic cells?
semi-synthetic penicillins
Which of the following drugs does NOT act by competitive inhibition? -streptomycin -sulfonamide -trimethoprim -ethambutol -isoriazid
streptomycin
Which one of the following does NOT belong with the others? -monobactum -bacitracin -streptomycin -cephalosporin -penicillin
streptomycin
The antimicrobial drugs with the broadest spectrum of activity are
tetracyclines
Protozoan and helminthic diseases are difficult to treat because
their cells are structurally and functionally similar to human cells
Drug resistance occurs
when abx are used indiscriminately
Which of the following methods of action would be bacteriostatic?
Inhibition of protein synthesis (or competetitive inhibition with folic acid synthesis)
Bacitracin
Inhibitor to cell wall synthesis
Cephalasporin
Inhibitor to cell wall synthesis
Fluoroquinolone
Inhibitor to nucleic acid synthesis
Tetracycline
Inhibitor to protein synthesis
Polymyxin B
Injury to plasma membrane
Which organisms would MOST likely be sensitive to natural penicillin?
Streptococcus pyogens
To date, mostof our natural abx have been found to be produced by members of what genus?
Streptomyces
Which of the following goes NOT constitute as an advantage of using to abx together?
Two are always twice as effective as one
Which antimicrobial agent is recommended for use against fungal infections?
amphotericin B
Antimicrobial peptides (AMPs) frequently work by
disrupting the plasma membrane
Which of the following statements about drug-resistance is FALSE?
it is only found in gram-negative bacteria
In the presence of penicillin, a cell dies because
it undergoes lyses
Which abx does NOT interfere with cell wall synthesis?
macrolides