Chapter 5 Lecture Slides Questions (cont'd)

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if you want to selectively label all types of nucleic acids being synthesized by cells, what radioactive compound would you add to the medium?

32P-labeled phosphate

ceviche is prepared by marinating fresh raw fish in citrus juice for several hours, until the flesh becomes opaque and firm as though it were cooked. how does citrus juice render the seafood safe to eat?

acidic pH denatures (unfolds and inactivates) proteins by disrupting their hydrogen bonds

the R group or side chain of the amino acid serine is -CH2-OH the R group or side chain of the amino acid alanine is -CH3 where would you expect to find these amino acids in a globular protein in an aqueous solution?

alanine would be in the interior, and serine would be on the exterior of the globular protein. alanine has a nonpolar group, making it hydrophobic. serine has a polar group, making it hydrophilic.

what kind of chemical bonds are found between paired bases of the DNA double helix?

hydrogen

sickle-cell disease is caused by a mutation in the beta-hemoglobin gene that changes a charged amino acid, glutamic acid, to valine, a hydrophobic amino acid. where in the protein would you expect to find glutamic acid?

on the exterior surface of the protein

what is a polymer of many amino acids linked by peptide bonds?

protein


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