Check Your Understanding Unit 2

the strength of the bond between oxygen and hemoglobin is known as the a. Bohr effect b. oxygen-hemoglobin affinity c. dissociation curve d. hemoglobin synthesis

b. oxygen-hemoglobin affinity

While in the hospital for management of acute lymphoid leukemia (ALL), a patient develops severe thrombocytopenia. The most appropriate action for this condition is A. anticoagulant therapy B. chemotherapy C. activity restriction D. isolation

C. activity restriction

A 5 year old patients parents report loss of appetite and fatigue in their child. The parents also state that the child refuses to walk as a result of pain. The child's most likely diagnosis is a. ALL (acute lymphoid leukemia ) b. CLL (chronic lymphoid leukemia) c. AML (acute myeloid leukemia) d. CML (chronic myeloid leukemia)

a. ALL (acute lymphoid leukemia)

Which type of leukemia primarily affects children? a. ALL (acute lymphoid leukemia) b. CLL (chronic lymphoid leukemia) c. AML (acute myeloid leukemia) d. CML (chronic myeloid leukemia)

a. ALL (acute lymphoid leukemia)

Which disorder is considered a primary immunodeficiency disease? a. HIV/AIDS b. malnutrition immunodeficiency c. cancer immunodeficiency d. radiation immunodeficiency

a. HIV/AIDS

velocity of blood flow is measured in a. cm per second b. mm per second c. yards per hour d. km per min

a. cm per second

Severe Combined Immunodeficiency (SCID) syndrome is an example of a. deficient immune response b. excessive immune response c. primary acquired immunodeficiency d. hypersensitivity reaction

a. deficient immune response

a lab test finding helpful in confirming the diagnosis of iron deficiency anemia is a. elevated total iron binding capacity b. elevated MCHC and MCV c. elevated total and indirect bilirubin d. postitive direct or indirect Coombs test

a. elevated total iron binding capacity

The major cause of death from leukemic disease is a. infection b. malnutrition c. hypovolemic shock d. kidney failure

a. infection

Dysfunction of which organ would lead to clotting factor deficiency? a. liver b. kidney c. spleen d. pancreas

a. liver

which causes vasoconstriction? a. norepinephrine b. calcium channel blocker c. a-Adrenergic antagonist d. acetylcholine

a. norepinephrine

What is the correct definition of complete remission (CR) of leukemia a. CR is the absence of leukemic cells in the blood b. CR is less than 5% marrow and normal CBC values c. CR is absence in leukemic cells regardless of CBC values d. CR is less than 5% leukemic cells in the blood

b. CR is less than 5% in marrow and normal CBC values

When the systemic vascular resistance is decreased, blood flow a. increases b. decreases c. stays the same d. moves to the extremities

b. decreases

widespread activation of the clotting cascade secondary to massive trauma is called a. hemophilia B b. disseminated intravascular coagulation (DIC) c. hageman disease d. idiopathic thrombocytopenic purpura

b. disseminated intravascular coagulation (DIC)

pernicious anemia is caused by the lack of a. iron b. intrinsic factor c. folate d. erythropoiethin

b. intrinsic factor

A cause of thrombocytopenia includes a. hypoxemia b. reduced erythropoietin c. chemotherapy d. secondary polycythemia

c. chemotherapy

The most effective therapy for anemia associated with kidney failure is a. iron administration b. high protein diet c. erythropoietin administration d. vitamin B12 and folate administration

c. erythropoietin administration

treatment for hemophilia A includes a. heparin administration b. factor IX replacement c. factor VIII replacement d. platelet transfusion

c. factor VIII replacement

A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) are characteristic of which type of anemia? a. vitamin B12 deficiency b. folate deficiency c. iron deficiency d. erythropoietin deficiency

c. iron deficiency

A deficiency of von Willebrand factor impairs a. activation of coagulation cascade b. platelet aggregation c. platelet adhesion to injured tissue d. platelet production

c. platelet adhesion to injured tissue

A patient is diagnosed with a tortuous blood vessel of the right hand that bleeds spontaneously. This patient presents with a. petechiae b. purpura c. telangiectasia d. thrombocytosis

c. telangiectasia

Patients with immunodeficiency disorders are usually first identified because they a. run high fevers b. have unusually high WBC counts c. develop brian infections d. develop recurrent infections

d. Develop recurrent injections

The principle Ig mediator of type I hypersensitivity reactions is a. IgA b.IgG c. IgM d. IgE

d. IgE

Patients who experience anemic episodes when exposed to certain drugs most likely have a. thalassemia b. spherocytosis c sickle cell anemia d. glucose-6-phosphate dehydrogenase deficiency

d. glucose-6-phosphate dehydrogenase deficiency

Which condition is associated with an elevated reticulocyte count? a. renal disease b. aplastic anemia c. hypertension d. hemolytic anemia

d. hemolytic anemia

A important mediator of a type 1 hypersensitivity reaction is a. complement b. antigen-antibody immune complexes c. T cells d. histamine

d. histamine

the megakaryocyte is a precursor to a. factor XI b. white blood cell c. red blood cell d. platelets

d. platelets

The goal of long term heparin for the management of a DVT a. relieve edema b. prevent clot dislodgement c. dissolve the thrombus d. prevent further clot formation

d. prevent further clot formation

A serious complication of DVT is a. stroke b. hypertensive crisis c. extremity necrosis d. pulmonary embolism

d. pulmonary embolism

an increase in hemoglobin affinity for oxygen occurs with a. hyperthermia b. shift to the right c. elevated PCO2 d. shift to the left

d. shift to the left

Hemophilia B is also known as christmas disease true false

true

The anemia resulting from a deficiency of either vitamin B12 (cobalamin) or folate is caused by a disruption in DNA synthesis of the blast cells in the bone marrow that produces very large abnormal bone marrow cells called megaloblasts. true false

true

The liver is responsible for the synthesis of coagulation factors, with the exception of part of VIII true false

true

The only known curative treatment for CML is allogeneic bone marrow transplantation from a suitable donor. true false

true

Burkitt's lymphoma is most closely associated with A. epstein-barr virus B. radiation exposure C. immunodeficiency syndromes D. history of cigarette smoking

A. epstein-barr virus

Risk factors for atherosclerosis A. female gender B. hyperlipidemia C. High protein diet D. low fibre diet

B. hyperlipidemia

Which condition enhances lymphatic flow? A. increased tissue hydrostatic pressure B. increased interstitial fluid colloid osmotic pressure C. decreased capillary hydrostatic pressure D. increased capillary oncotic pressure

B. increased interstitial fluid colloid osmotic pressure

Clinical manifestations if chronic arterial obstruction include A. edema B. intermittent claudication C. decreased pressure proximal to the obstruction D. distal hyperemia

B. intermittent claudication

A 58 year old woman is seen in the clinic for reports of severe back pain. Her chest x-ray demonstrates generalized bone demineralization and compression fracture. Blood studies demonstrate elevated calcium levels. The mostly likely diagnosis is a. leukemia b. myeloma c. hodgkin disease d. back trauma

B. myeloma

Blood flow throughout the periphery is regulated by A. cardiac output B. the autonomic nervous system C. velocity D. hemodynamics

B. the autonomic nervous system