Chemistry

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When the body compensates for a respiratory or metabolic disorder, the MAIN goal is to achieve: Please select the single best answer correct carbonic acid level, since it is the most important system in the body a normal pH normal p02 and pCo2 for normal respiration correct bicarbonate level, since it is the most important system in the body

A normal pH

Which CSF tube goes to which department in a 3-tube collection?

#1 to chemistry #2 to microbiology #3 to hematology

the formula for conversion for HbA1c to glucose in mg/dL is eAG = (28.7 * A1c) - 46.7 what is the eAG is the measured A1c is 7.5%?

169mg/dL

Calculate the results in mg/24hr for a 24 hour urine protein. Total volume= 2,400mL Urine Protein= 2.7 mg/dL

64.8 mg/24hr

If Na=145 mmol/L Cl-=113 mmol/L Bicarb= 24 mmol/L calculate the anion gap

8 mmol/L normal is 10-20 mmol/L

What is the legal limit for blood ethanol in order to drive?

80 mg/dL

the normal De Ritis ratio (AST/ALT) is <=1 2:1 3:1 4:1

<=1 (less than or equal to 1)

The tumor marker associated with ovarian cancer is

CA-125

Which laboratory assay is a highly specific indicator and the most sensitive assay for the diagnosis of rheumatoid arthritis?

Cyclic Citrullinated Peptide (CCP)

A low CSF glucose level is associated with

Fungal meningitis, Amebic meningitis, Trichinosis meningitis Hyperglycemia will result in a normal or elevated CSF glucose level

Which of the following conditions argues in favor of Therapeutic Drug Monitoring for a specific drug? Low degree of protein binging Given chronically Low toxicity and few side effects Effective and toxic concentrations are not well defined

Given chronically

What is the expected serological response in an immunocompetent patient who has been vaccinated for Hepatitis B (HBV)?

HBsAg(neg), Anti-HBc(neg), Anti-HBS(pos)

What autoantibody is found in Type I Diabetes Mellitus?

Islet cell antibodies

Which testing method is appropriate for identifying specific allergens?

RAST (Radioallergosorbent tests)

What is the formula for calculating anion gap?

Sodium - (Chloride + Bicarb)

What autoantibodies are found in a patient with Hashimoto's thyroiditis?

TPO- Antithyroid Peroxidase

What autoantibody is present in Grave's disease?

TRAbs- Thyroid Stimulating Hormone Receptor Antibodies

What conclusion can be made if a patient has an abnormal cardiac risk marker?

That person has a higher probability of developing cardiac disease. They are not guaranteed to develop disease, just as someone with normal risk factors is not immune to disease.

Which of the following is a biomarker for acute coronary syndrome? Smoking Obesity High-Sensitivity C-Reactive Protein (hsCRP) Hypertension

hsCRP

How do plasma glucose levels compare to self-monitored whole blood glucose (SMBG)?

Whole blood is 11% lower

A decreased serum copper level and an increased urine copper level is most consistent with

Wilson's disease

increased concentrations of AFP in adults are most characteristically associated with

hepatocellular carcinoma

cholesterol is used by the body for what function?

hormone precursor

If CSF tubes numbered 1, 2 and 3 can not be analyzed within 1 hour, the correct procedure for the microbiology sample is to:

leave it at room temperature tube 1 is for chem and can be frozen tube 2 is for micro and refrigeration or freezing will kill Neisseria Meningitides (if present) so it must be kept at room temp tube 3 is for hematology cell counts and can be refrigerated

In a normal CSF the protein concentration as compared to plasma is generally less than 1% 10% 30% 50%

less than 1%

which of the following is most likely to interfere with the measurement of hemoglobin? leukocytopenia EDTA lipemia heparin

lipemia increased turbidity in the sample can lead to falsely elevated hemoglobin measurements

which 24 hour urine assay is the best single screening test for pheochromocytoma?

metanephrines

Which cardiac marker is elevated first in the case of myocardial infarction (MI)?

myoglobin

What autoantibody causes Celiac disease?

tTG- Antitransglutaminase


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