CITI Quiz 3-Planning Research and Completing the Protocol Form

USDA Category C activities?

Category C of the USDA report form applies to "animals upon which teaching, research, experiments, or tests were conducted involving no pain, distress, or use of pain relieving drugs." Superficial blood collection, postmortem tissue collection, and non-invasive observation would generally not involve greater than momentary or slight pain or distress. Surgery is a painful procedure and would disqualify an animal from USDA category C.

USDA Category D activities?

Category D of the USDA report form applies to "animals upon which experiments, teaching, research, surgery, or tests were conducted involving accompanying pain or distress to the animals and for which appropriate anesthetic, analgesic, or tranquilizing drugs were used."

Example of refinement?

Refinement, in the context of the 3 Rs, includes methods that refine animal use by lessening or eliminating pain or distress and, thereby, enhancing animal well-being. One example of refinement is the use of newer surgical techniques that result in less tissue trauma.

What is the primary purpose of the "3 R's" concept?

The primary purpose of the "3 Rs" is to urge investigators to minimize use of animals and minimize pain and distress caused by animal research.

What helps the IACUC when reviewing an animal protocol

flowcharts to illustrate complex experimental designs.