Diffuse Lymphoid Tissue Histology

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guard the pharynx (common tube for digestive & respiratory tracts)

Tonsils (in ring of Waldeyer): singular are pharyngeal and lingual, paired are palatine

macrophage (prominent nucleolus and big euchromatic pale nucleus)

blue circle

situated in the transition zone between nasal cavity & pharynx; covered with stratified squamous epithelium and pseudostratified ciliated columnar epithelium with goblet cells (so upper "nasal" portion is lined by respiratory epithelium)

pharyngeal tonsils

blast cells in germinal center (aka lymphoblasts)

red circles

secondary nodules (w/ pale germinal centers since nuclei are farther apart in stimulated lymphocytes)

type of majority of nodules in the tonsils

small numbers of white blood cells in connective tissue underlying epithelial cells - region will have an overall basophilic appearance when compared to other surrounding connective tissue

Diffuse lymphoid tissue

blast cells in germinal centers of palatine tonsils (aka lymphoblasts)

ID black arrows

macrophage in palatine tonsils

ID red arrow

macrophages in germinal centers of palatine tonsils

ID red arrows

blast form (largest nuclei, clearly dividing cells) of lymphocytes in germinal center of secondary nodules in palatine tonsils

ID the black arrows

septa

ID the green arrows

septum

ID the green arrows

mitotic figures (lymphocytes undergoing proliferation in the germinal center)

ID the green circles

corona (thicker side) of secondary nodules of palatine tonsils

ID the yellow area

tonsillar crypt

ID the yellow arrows

tonsillar crypts

ID the yellow arrows

palatine tonsillar tapered cells w/ flattened nuclei: reticular cells (synthesize collagen framework) or dendritic cells (process and present antigen to lymphocytes)

ID yellow arrows

specialized diffuse lymphoid tissue in small intestine, digestive tract

Peyer's patches


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