Genetics Chapter 19: Gene Mutation, DNA Repair, and Recombination

The region where two chromosome pieces break and re-attach to other chromosome pieces is called a chromosomal ______

Breakpoint

Mutations in the 5'-UTR or 3'-UTR of an mRNA molecule are most likely to affect what?

The mRNA's ability to be translated The stability of the mRNA

The phenomenon in which a repeated sequence of three nucleotide bases increases in number generation after generation is called _____

trinucleotide repeat expansion

What type of mutations involve a change from a normal codon to a stop codon?

Nonsense mutations

Changes to DNA structure caused by reactive oxygen species (ROS) are termed ______

Oxidative DNA damage

The addition or deletion of a number of bases that is not a multiple of 3 causes a(n)_____

frameshift mutation

A base substitution in DNA that ultimately leads to a change in the encoded amino acid is called a(n)____

missense mutation

Mutations in eukaryotic genes that change the _____recognition sequences may affect the order and/or number of exons contained in the mature mRNA.

splicing