Immunoglobulins Quiz: List the Ig Type
IgM
5 times larger than IgG
IgM
5 to 10% of circulating immunoglobulins
IgG
80% of total if >2 years old
IgD
Accounts for <1% of all immunoglobulins
IgA
Accounts for about 10 to 13% antibodies, but only small proportion are circulating
IgA
Antibodies bind to microorganisms and prevents attachment and colonization
IgG
Can cross placenta
IgE
Bound to basophils and mast cells where it causes the release of potent chemicals from granules if the specific antigen binds to it
IgG
Interacts with complement to aid in phagocytosis
IgG
Most Ig in circulation
IgA
Most are associated with mucous membranes, saliva, or breast milk
IgM
Most efficient antibody in interacting with complement to aid in phagocytosis
IgG
Neutralize toxins
IgM
Opsonizing antibody that increases phagocytosis
IgG
Prevent adherence of viruses and microorganisms to host cells
IgE
Responsible for allergic or hypersensitivity reactions (hay fever, hives, asthma)
IgA
Secretory Ig in breast milk protects against intestinal pathogens
IgA
Secretory component transports molecule onto surface of mucous membrane and protects it from destruction by proteolytic enzymes
IgD
Similar in structure to IgG
IgA
Structurally: appear as dimers (secretary )
IgM
Structure in the blood is a pentamer of 5 subunits = 10 antigen binding sites
IgM
Very efficient in agglutination
IgE
Barely detectable in blood
IgM
In some cases is the only class of antibodies produced against some antigen (eg capsular polysaccharides of bacteria)
IgM
First immunoglobulin produced after antigen exposure
IgD
Found mostly on the surface of B lymphocytes
IgD
Function not clearly defined
IgD
Functions during the development and maturation of the antibody response
