Pharm

Question 16 A patient's serum protein and albumin levels are low. For a drug that is highly protein bound, there would be: Select one or more: a. c. more drug bound to protein b. a. more free drug in circulation c. b. less free drug in circulation d. d. more drug excreted in the urine

B

Question 19 A 300mg drug has a half life of 4 hours. How many milligrams of the drug will there be after 1 half life? Select one or more: a. d. 37.5 mg b. b. 150mg c. c. 75mg d. a. 300mg

B

Question 5 A nurse is determining if a medication is ordered to be given at the appropriate intervals. This is done by assessing the half-life of the medication. The serum half-life (t1/2) of a drug is: Select one: Select one or more: a. a. the time required for half of the drug dose to be completely distributed b. d. the time required after absorption for half of the drug to be eliminated c. c. the time required for half of a drug dose to be absorbed d. b. the time required for a drug to be effective

B

Question 17 While caring for a patient with liver disease, the nurse knows which abnormalities in which phase of pharmacokinetics may occur? Select one or more: a. a. absorption b. d. excretion c. c. metabolism d. b. distribution

C

Question 2 When providing a medication, if the nurse wanted to select the route that ensures greatest bioavailability, that route is: Select one: Select one or more: a. a. intramuscularly b. c. orally c. d. intravenously d. b. subcutaneously

C

Question 7 The nurse is administering parenteral drugs. Which statement is true? Select one or more: a. d. parenteral drugs exert their effects while circulating in the bloodstream. b. c. absorption of parenteral drugs is altered by the presence of food in the stomach. c. a. parenteral drugs bypass the first pass effect d. b. absorption of parenteral drugs is affected by reduced blood flow to the stomach.

C

Question 8 The nurse defines the drugs half life as (select one) Select one or more: a. a. the drug to elicit half of its therapeutic response. b. b. one half of the original amount of a drug to reach target cells. c. c. one half of the original amount of a drug to be removed from the body. d. d. one half of the original amount of a drug to be absorbed into the circulation.

C

Question 6 Of the drugs listed below, which would be affected by the first pass effect? Select all that apply. Select one or more: a. a. morphine infusion via patient controlled analgesia pump b. b. nitroglycerin sublingual tablets c. c. benadryl elixer d. d. levothyroxine (Synthroid) tablets e. e. transdermal nicotine patches f. f. nifedipine (Procardia) capsules g. g. penicillin via IV piggyback

C D F

Question 1 Question text A client is taking a drug that is moderately highly protein-bound. Several days later, the client takes a second drug that is 90% protein-bound. What happens to the first drug that is highly protein-bound? Select one or more: a. a. The second drug becomes less active. b. d. The first drug remains protein-bound. c. c. The first drug becomes increasingly inactive. d. b. The first drug is released from the protein and becomes freely active

D

Question 10 Absorption of a drug is affected by many factors. Drugs that absorb readily across the GI membranes are (select one) Select one or more: a. a. water soluble b. c. water soluble ionized drugs c. b. nonionized drugs d. d. lipid soluble

D

Question 11 A drug has a half life of 36 hours. The drug would probably be administered on a dosing schedule of: Select one or more: a. b. once a day b. c. twice a day c. d. every other day d. a. once a week

D

Question 18 A patient is taking an enteric coated medication. The nurse should include what statement? Select one or more: a. a. "Take the tablet with orange juice" b. c. Crush the tablet before swallowing c. b. Avoid taking all other medications with any enteric coated tablet d. d. Swallow whole without chewing

D

Question 3 A client's Creatinine Clearance is normal. Based on this information, the nurse would anticipate that the dose of the drug would be: Select one: Select one or more: a. a. decreased b. b. increased c. d. changed d. c. the same

D

Question 4 A client asks why the oral dose of his pain medication is higher than the intravenous dose. The nurse explains that with the oral dose, some of the drug is absorbed from the GI tract and is metabolized by the liver to an inactive drug form. This reduces the amount of active drug and is called (the): Select one: Select one or more: a. c. passive absorption b. d. Pinocytosis c. b. protein binding d. a. hepatic first pass

D

Question 12 Isoproterenol (Isuprel) is an example of a medication that enhances the receptors in the body. Drugs that enhance a response are known as: (select one) Select one or more: a. b. agonists b. d. therapeutic effect c. a. antagonists d. c. depressants

A

Question 13 A medication has a low therapeutic index. Which of the following nursing intereventions is indicated when administering this medication? Select one or more: a. c. monitor blood levels of the medication b. d. determine liver function before each dose c. a. ensure the patient voids before adminstation d. b. have emergency airway equipment at the bedside.

A

Question 14 \ A low therapeutic index indicates: (select one) Select one or more: a. b. drug is potentially lethal b. c. drug will be given once daily. c. d. drug will be effective in 50% of the population d. a. drug is relatively safe

A

Question 20 Not yet answeredMarked out of 1.00Not flaggedFlag question Question text If this same drug with 300 mg with 4 hr half life was given at 0800 am, what time of day will 97% of this drug be eliminated? Select one or more: a. a. 0000 midnight b. b. 2000 pm c. c. 1200 pm d. d. 1800 pm

A

Question 9 The duration of action is (select one) Select one or more: a. d. the time it takes for a drug's concentration to be sufficient to cause a therapeutic response. b. a. the time it takes for a drug to elicit a therapeutic response. c. b. the time it takes for a drug to achieve its maximum therapeutic response. d. c. the time it takes for a drug to be eliminated from circulation.

A