Pharmacology 13
A patient received an injection of doxorubicin and is now observing a reddish urine. The patient states, "Do you think I am bleeding?" What is the best response by the nurse?
"The reddish urine is harmless and an expected response to the drug."
A patient develops lysis syndrome during the administration of chemotherapy agents. Which of the following treatments is implemented to decrease the effects of lysis syndrome?
Administer regular insulin and IV sodium bicarbonate
A child is prescribed an anthracycline drug. The nurse would teach the parents to observe for signs and symptoms of what adverse effect?
Cardiotoxicity
A patient taking Tamoxifen to reduce the risk of contralateral breast cancer asks the nurse about adverse effects of the drug. What is an adverse effect of Tamoxifen?
Cerebrovascular accidents
A nurse is preparing an antineoplastic agent for a 9-year-old cancer patient. Before administering an antineoplastic agent, the nurse's most important action should be what?
Check indexes of bone marrow functioning
A patient who is receiving methotrexate is also receiving leucovorin. The nurse understands that this drug is being given for which reason?
Counteract effects of methotrexate
A patient is to receive doxorubicin as treatment for leukemia. The nurse would instruct the patient that the typical cycle would be repeated at which frequency?
Every 3 weeks
A patient has been administered methotrexate, which is a purine antagonist used to treat a rapidly growing tumor. The patient develops stomatitis. What is the priority nursing diagnosis for a patient suffering from stomatitis?
Impaired skin integrity
Which agent would the nurse expect to be administered orally
Methotrexate
A patient with non-Hodgkin's lymphoma (NHL) will be starting a course of doxorubicin shortly. When planning this patient's care, what nursing diagnosis should the nurse prioritize?
Risk for Infection related to suppressed bone marrow function
A nurse is providing patient education to a 50-year-old woman who is taking methotrexate (MTX) for breast cancer. The nurse will instruct the patient to avoid which of the following drugs?
Salicylates
What is the first action by the oncology nurse when observing extravasation with the patient receiving vincristine?
Stop the infusion.
A 42-year-old female with breast cancer has had a radical mastectomy. She will have radiation therapy and then begin chemotherapy. Drug therapy will consist of a combination of doxorubicin, cyclophosphamide, and paclitaxel. What will the nurse include in her teaching plan concerning the drug therapy?
Take special care when shaving or brushing her teeth
A 62-year-old patient taking tamoxifen exhibits increased bone and tumor pain along with a local disease flare. The nurse interprets this as an indication of which of the following?
The tumor responding to treatment
A patient who has been taking high-dose cyclophosphamide therapy has had sterile hemorrhagic cystitis. What measures can the oncology nurse take to reduce the risk of recurrence? (Select all that apply.)
• Administer mesna as ordered. • Prehydrate the patient orally and intravenously (IV) with 2 L of normal saline. • Monitor urine output.
If the nurse has to clean up a spill of antineoplastic drug, which of the following personal protective equipment should be worn? Select all that apply:
• Gloves • Safety goggles • Gown • NIOSH-approve respirator
After teaching a group of students about antineoplastic antibiotics, the instructor determines that the teaching was successful when the students identify which drug as an example?
Doxorubicin
A 54-year-old received a diagnosis of breast cancer several weeks ago and her current treatment regimen includes tamoxifen, a cell cycle-nonspecific antineoplastic drug. Which of the following is a characteristic of a cell cycle-nonspecific drug?
The drug is effective regardless of whether a cancerous cell is proliferating.
The nurse should monitor a client receiving doxorubicin (Doxil) for signs of extravasation that include which of the following? Select all that apply:
• Swelling • Lack of blood return • Redness
Which of the following antineoplastic drugs are classified as a plant alkaloid? Select all that apply:
• Vincristine (Oncovin) • Paclitaxel (Taxol) • Etoposide (Toposar) • Irinotecan (Camptosar)
