True False Questions-Genetics
A molecule that consists of a nitrogenous base bonded to the 1' carbon of a ribose or deoxyribose is a nucleotide.
FALSE
A promoter is a sequence where DNA replication is initiated.
FALSE
A special tRNA not carrying an amino acid binds to stop codons to terminate translation.
FALSE
A, B, and Z-form DNA are all right handed helixes.
FALSE
All eukaryotic genes contain an intron.
FALSE
All living organisms use DNA as their genetic material.
FALSE
All organisms contain DNA that is roughly 25% A, 25% T, 25% G, and 25% C.
FALSE
All types of RNA are translated to proteins.
FALSE
An mRNA can be translated by only one ribosome at a time in prokaryotic cells.
FALSE
Avery, MacLeod, and McCarty showed that DNA is the genetic material of cells and that RNA is the genetic material of viruses.
FALSE
B-DNA's shape is in general longer and narrower than Z-DNA's shape.
FALSE
Both eukaryotes and prokaryotes typically have only one origin of replication.
FALSE
DNA helicase binds to the double-strand DNA ahead of the replication bubble and reduce the supercoiling of double helix DNA.
FALSE
DNA polymerases always synthesize new DNA by adding nucleotides on to the 5' phosphate.
FALSE
During translation initiation, the large subunit is the first part of the ribosome to associate with the mRNA.
FALSE
Genetic information is transferred from Protein to RNA to DNA.
FALSE
If an mRNA has the codon 5' UAC 3', the tRNA anticodon binding to it will be 5' AUG 3'.
FALSE
In all organisms, all genes are transcribed from the same strand.
FALSE
In eukaryotes, the 5' cap and the 3' poly-A tail are involved in translation termination.
FALSE
Okazaki fragments are involved in both lagging and leading DNA strand synthesis.
FALSE
Origin of replication is necessary for RNA polymerase to recognize the promoter of a bacterial gene.
FALSE
Prokaryotic promoters contain the sequence TATAAT at the position -45 from the transcription start.
FALSE
RNA polymerase "reads" a template strand from 5' to 3'.
FALSE
RNA primers are required for eukaryotes transcription.
FALSE
Sigma subunits dissociate from RNA polymerase after transcription has terminated
FALSE
Single-strand binding proteins prevent DNA polymerase from entering a replication initiation site.
FALSE
The 5' and 3' untranslated regions (UTRs) of processed mRNA molecules are derived from introns.
FALSE
The 5' cap on an mRNA is important for the transcription initiation of an mRNA molecule.
FALSE
The B form and A form are both twisted into a left-hand helix, but the A form is shorter and wider than B-DNA.
FALSE
The codon for methionine appears only at the beginning of the mRNA for a protein, not in the middle or at the end.
FALSE
The eukaryotic RNA polymerase II is responsible for all types of RNA transcription.
FALSE
The poly(A) tails on mRNA molecules are transcribed from DNA templates.
FALSE
The proofreading function of DNA polymerases involves 5'---->3' exonuclease activity.
FALSE
The spliceosome is a large, ribonucleoprotein complex located in the cytoplasm.
FALSE
Theta replication utilizes only a unidirectional replication fork.
FALSE
There are 3 hydrogen bonds between A-T pairs.
FALSE. 2
A protein called Tus facilitates the initiation of replication in E. coli.
TRUE
Complementary base-pairing rules mean that, given one strand of DNA, the base sequence of the other strand can be determined.
TRUE
DNA ligase joins Okazaki fragments together after the RNA primers are replaced with DNA.
TRUE
DNA polymerases require both a template and a primer to initiate synthesis of new DNA.
TRUE
DNA synthesis during replication is initiated from RNA primers.
TRUE
During translation initiation in prokaryotes, 165 rRNA base-pairs with a piece of sequence in mRNA to position a ribosome at the start codon.
TRUE
During translation initiation in prokaryotes, the initiator tRNA (f-met) binds to the P-site of a ribosome.
TRUE
Eukaryotic promoters do not have the same -10 and -35 consensus sequences that prokaryotic promoters have.
TRUE
Gene expression is one of the research focuses in molecular genetics.
TRUE
Griffith demonstrated that a transforming chemical from dead bacteria could change the genetic information of living bacteria.
TRUE
If a double stranded DNA molecule is 30% G, then C must also be 30%. The remaining 40% must be A and T with 20% of each.
TRUE
In prokaryotes, rho-independent transcription termination depends on a secondary structure formed in the RNA that is being transcribed.
TRUE
In transcription, nucleotides are always added to the 3' end of the elongating strand.
TRUE
Initiation of transcription does not require a primer.
TRUE
Intron cleavage and exon splicing are both mediated by the spliceosome.
TRUE
Multiple forms of a gene are called alleles.
TRUE
Multiple protein products are often produced from single eukaryotic genes.
TRUE
RNA can form a secondary hairpin structure.
TRUE
RNA is usually a single-stranded molecule instead of a hydrogen-bonded double strand like DNA.
TRUE
Regulatory promoter for eukaryotic RNA polymerase II is immediately upstream of the core promoter.
TRUE
Ribosomes move along an mRNA in the 5' to3' direction.
TRUE
Rolling-circle replication is unidirectional and produce multiple circular DNA molecules.
TRUE
The TATA-binding protein (TBP) in the transcription factor binds to the TATA box sequence in eukaryotic promoters to initiate the transcription.
TRUE
The bonds that connect nucleotides in a strand are called phosphodiester bonds.
TRUE
The different types of eukaryotic RNA polymerases recognize different gene's promoter sequences.
TRUE
The function of aminoacyl-tRNA synthetases is to attach amino acids to tRNAs.
TRUE
The genetic code is said to be "degenerate" because there are more codons than amino acids.
TRUE
The helicase activity of rho protein primarily causes termination of transcription.
TRUE
There are 64 different codons, which encode 20 amino acids and 3 stop codons.
TRUE
Transcribed RNA molecule has the same sequence as the non-template strand, except that U replaces T.
TRUE
Uracil is similar to thymine except that uracil lacks a methyl group on the carbon at position 5 on the carbon at position 5 on the carbon-nitrogen ring.
TRUE
With respect to their 3' and 5' ends, the two polynucleotide chains of a double-stranded DNA molecule are antiparallel.
TRUE
tRNA molecules play an important role in translation.
TRUE
