3.6 - Fibrosarcoma

Cells in fibrosarcoma

Fibroblastic in appearance with a somewhat uniform spindle shape May be arranged in fascicles creating a herring bone pattern

Fibrosarcoma lab

Notta

S/Sx of fibrosarcoma

Pain and swelling Largest soft tissue mass

How are fibrosarcoma's grouped

By patient age Anatomical region

What does the name fibrosarcoma mean

Fibro - fibers Sarcoma - Connective tissue tumor

What are some different kinds/locations of fibrosarcoma

Fibrosarcoma of the breast Fibrosarcoma of the chest wall Fibrosarcoma of the bone Ovarian fibrosarcoma Infantile fibrosarcoma of the lung

Radiographic findings for fibrosarcoma

High destructive lytic with a wide zone of transitioin Occasionally expansile Lesion usually has no matrix mineralization, but may have areas of sequestrated bone Often associated with a large soft tissue mass

Distribution of fibrosarcoma

Long bones 70% of the time Metaphysis is common but can extend beyond

Epidemiology of fibrosarcoma

Males 30-60

What kind of tumor is fibrosarcoma

Malignant

What is a fibrosarcoma

Malignant tumor of fibroblast origin

Two types of fibrosarcoma

Primary Secondary

What are fibrosarcomas secondary to

Radiation treatment Dedifferentiation from other tumors or pathologies such as paget's disease, bone infarction, chronic osteomyelitis

Extracellular collagen fibril appearance in fibrosarcoma

Typical

How prevalent is fibrosarcoma

Very rare

Most common location of fibrosarcoma

Distal femur Proximal tibia

Contraindications to adjust with fibrosarcoma

Don't adjust in area of known or suspected malignancy Spread Fracture