Adams Ch 40 - Drugs for Asthma and Other Pulmonary Disorders

Cromolyn can replace Corticosteroids (in case of allergy, ineffectiveness, or contraindications) corticosteroids or cromolyn: neither effective for acute attacks

((If a pt is allergic to corticosteroid medications, which medication can they be prescribed))

Albuterol (Proventil HFA, Ventolin HFA, VoSpire ER) Adverse Effects: Palpitations. Headaches. Throat irritation. Tremor. Nervousness. Restlessness. Tachycardia. Insomnia. Dry mouth. Chest pain (uncommon). Paradoxical bronchospasm (uncommon). Allergic reactions (uncommon).

Albuterol SABA

ASTHMA: acute asthma attacks... inhaled albuterol (Proventil HFA, Ventolin HFA) (15 mins) not oral albuterol (VoSpire ER) INSABAPROVENT ORALABAVO Peak expiratory flowmeter evaluate asthma med effectiveness

asthmatic pt's smooth muscles in airway are hyperresponsive to stimuli resulting in bronchospasm and inflammation during an asthma attack, histamines and prostaglandins are released Activation of beta2-adrenergic receptors would = bronchodilation potential asthma triggers: air pollution, allergens, chemicals & food, URI's, stress, exercise, weather to avoid acute asthma attacks, pt should avoid dust pollen and mold cold air can trigger an acute attack short-acting bronchodilator should be used during acute attack sudden airway hyperresponsive to stimuli? asthma attack

Drug/Drug Contraindications for albuterol? Beta blockers -inhibit albuterol's bronchodilation effect monoamine oxidase inhibitors (MAOIs) for 14 days after beginning albuterol therapy ((risk for hypertensive crisis))

not contraindicated: corticosteroids leukotriene modifier (singulair) mast cell stabilizer