ALAT Chapter 16 Practice Test

When is the hypothesis developed during a research study? a. At the very beginning, when planning the study b. At the very end, when writing up the results c. After the animal use protocol is approved by the IACUC d. Before ordering the animals

a. At the very beginning, when planning the study

In a research study, what is a variable? a. Factors or conditions that can change the results or outcome of a study b. The part of the protocol that specifies the animal use c. The group of animals that receives the experimental treatment d. The type of approval given by the IACUC

a. Factors or conditions that can change a study

In a research experiment testing a new drug, which group of animals receives the test substance? a. The experimental group b. The control group c. The baseline group d. The sentinel group

a. The experimental group

Although the IACUC must approve all new studies before they can begin, researchers may add new experimental groups or procedures during the study without IACUC approval. a. True b. False

b. False

Planned or controlled manipulations within a research study are called: a. non-experimental variables. b. experimental variables. c. designed change factors. d. non-designed change factors.

b. experimental variables

Which of the following is a non-experimental variable that could interfere with research results? a. Genetic manipulation b. Changing cages on time every week c. Mistake in recording data d. Injection of test substance

c. Mistake in recording data

In a research experiment, what is the term to describe the group of animals that does not receive the experimental treatment? a. The sentinel animals b. The baseline animals c. The control animals d. The experimental animals

c. The control animals

In a research protocol, what are the humane endpoints? a. The steps that will lead to the end of the research study b. The criteria used to determine which animals will be placed in the experimental group c. The criteria used to determine when an animal should be euthanized d. The criteria used to search if the study is unnecessarily duplicative

c. The criteria used to determine when an animal should be euthanized

In most facilities, no research experiments on live vertebrate animals may begin before the experiments are approved by: a. the USDA. b. OLAW. c. the IACUC. d. the FDA.

c. the IACUC

Which of the following best describes the experimental design of a study? a. The detailed description of how the animals will be euthanized and how their carcasses will be disposed of b. A step by step protocol describing how animals will be used in the study, including all procedures, drugs, and manipulations done to the animals c. The written narrative describing the justification to use live animals in research d. A plan that describes the methods used to answer the research question or hypothesis

d. A plan that describes the methods used to answer the research question or hypothesis

Which of the following is an example of basic research? a. Testing the safety of a new antibiotic ointment b. Testing a new drug therapy for Parkinson's disease c. Using cows for developing a new vaccine for chicken pox d. Studying the normal brain function of rats

d. Studying the normal brain function of rats