Bone Growth and Remodeling
Step 3 of interstitial growth within Cartilage
chondrocytes divide
hypertrophic cartilage
chondrocytes mature, appear in columns
step 3 of appositional growth
osteoblasts in endosperm build new concentric lamella inward toward center of tunnel forming a new osteon
diaphysis (bone)
what is located right below the epiphyseal plate?
appositional growth
-growth at the outer surface -growth in width
interstitial growth
-growth from within the cartilage -growth in the length at epiphyseal plate
Step 2 of interstitial growth within Cartilage
Chondroblasts build matrix and differentiate into chondrocytes
Step 4 of interstitial growth within Cartilage
Chondrocytes build matrix and spread apart
-resting cartilage -proliferating cartilage -hypertrophic cartilage -calcified cartilage -diaphysis (bone)
What is the layering of the ends of long bones? (superficial to deep)
the papillary layer
What supplies the blood vessels to the cartilage?
Periosteal and Endosteal
What does types of cells are involved in appositional growth?
osteoclasts come in and destroy and form spongy bone
What happens to the calcified cartilage region in order to cause the lengthen in bone?
Step 5 of interstitial growth within Cartilage
cartilage tissue grows from within
when the osteoclasts/ osteoblasts work faster than the chondrocytes In the proliferating zone --- epiphyseal plate closes and becomes the epiphyseal line
When does growth in length of bone stop?
because it is avascular
Why does cartilage heal slowly?
proliferating cartilage
Zone of the epiphyseal plate where the cells are actively dividing (this is where the bone physically begins to lengthen
osteons
appositional growth generates new ______?
step 4 of appositional growth
bone grows outward as osteoblastsin periosteum build new circumferential lamella. osteon formation repeats as new periosteal ridges fold over blood vessels
Periosteal osteoblasts
build bone on outer surface of bone
general rule "blasts"
build up
calcified cartilage
dead chondrocytes that stack up over time
endosteal osteoclasts
increase the diameter of the marrow cavity
growth of cartilage
interstitial growth and appositional growth
general rule "cytes"
maintain
Step 1 of interstitial growth within Cartilage
mesenchyme cells differentiate into chondroblasts
step 2 of appositional growth
periosteal ridges fuse forming an endosperm lined tunnel
resting cartilage
reserve cartilage that decreases in size as we age located above the epiphyseal plate
step 1 of appositional growth
ridges in periosteum create groove for periosteal blood vessel