Bone Growth and Remodeling

Step 3 of interstitial growth within Cartilage

chondrocytes divide

hypertrophic cartilage

chondrocytes mature, appear in columns

step 3 of appositional growth

osteoblasts in endosperm build new concentric lamella inward toward center of tunnel forming a new osteon

diaphysis (bone)

what is located right below the epiphyseal plate?

appositional growth

-growth at the outer surface -growth in width

interstitial growth

-growth from within the cartilage -growth in the length at epiphyseal plate

Step 2 of interstitial growth within Cartilage

Chondroblasts build matrix and differentiate into chondrocytes

Step 4 of interstitial growth within Cartilage

Chondrocytes build matrix and spread apart

-resting cartilage -proliferating cartilage -hypertrophic cartilage -calcified cartilage -diaphysis (bone)

What is the layering of the ends of long bones? (superficial to deep)

the papillary layer

What supplies the blood vessels to the cartilage?

Periosteal and Endosteal

What does types of cells are involved in appositional growth?

osteoclasts come in and destroy and form spongy bone

What happens to the calcified cartilage region in order to cause the lengthen in bone?

Step 5 of interstitial growth within Cartilage

cartilage tissue grows from within

when the osteoclasts/ osteoblasts work faster than the chondrocytes In the proliferating zone --- epiphyseal plate closes and becomes the epiphyseal line

When does growth in length of bone stop?

because it is avascular

Why does cartilage heal slowly?

proliferating cartilage

Zone of the epiphyseal plate where the cells are actively dividing (this is where the bone physically begins to lengthen

osteons

appositional growth generates new ______?

step 4 of appositional growth

bone grows outward as osteoblastsin periosteum build new circumferential lamella. osteon formation repeats as new periosteal ridges fold over blood vessels

Periosteal osteoblasts

build bone on outer surface of bone

general rule "blasts"

build up

calcified cartilage

dead chondrocytes that stack up over time

endosteal osteoclasts

increase the diameter of the marrow cavity

growth of cartilage

interstitial growth and appositional growth

general rule "cytes"

maintain

Step 1 of interstitial growth within Cartilage

mesenchyme cells differentiate into chondroblasts

step 2 of appositional growth

periosteal ridges fuse forming an endosperm lined tunnel

resting cartilage

reserve cartilage that decreases in size as we age located above the epiphyseal plate

step 1 of appositional growth

ridges in periosteum create groove for periosteal blood vessel