Chapter 10 Muscles
What are the characteristics of skeletal muscle
excitability, conductivity, contractility, elasticity, extensibility
The majority of muscle fibers in the body are
fast glycolytic
Intermediate fibers have a high resistance to ____
fatigue
What are some examples of isometric contractions
holding a yoga pose pushing on a locked door sitting up very straight
What percentage of body weight is muscle tissue in an adult
40% to 50%
What is a fasicle
A bundle of muscle fibers
What houses muscle fibers
A fascicle Muscle fibers are bundled within a fascicle Many fascicles are bundled within the whole skeletal muscle
What is a single muscle made of
A single muscle is composed of thousands of muscle cells
What causes a local change in the resting membrane potential
A stimulus
What type of connective tissue is a tendon made of
A tendon is made of dense regular connective tissue
What is contractility
Enables muscle cells to cause body movement and to perform the other functions of muscles Is exhibited when contractile proteins within skeletal muscle cells slide past one another.
What is a tendon
A thick cordlike structure that attaches muscle to bone
When muscle fiber contracts, which parts of the sarcomere maintain a constant length throughout contraction
A-band
What is the order of events once ACh diffuses across the synaptic cleft of a NMJ
ACh binds to receptors on the motor end plate The resulting action potential moves down the sarcolemma The action potential moves down the t-tubules The action potential reaches the terminal cisternae of the sarcoplamic reticulum Calcium ions are released into the sarcoplasm
What is excitability?
Ability of a cell to respond to a stimulus
What is acetylcholine?
Acetylcholine is a neurotransmitter that enables the communication between muscles and motor neurons
What is the double stranded contractile protein
Actin
Which of the following proteins ae found within a sarcomere
Actin and connectin
What is the name of the connective tissue that separates muscle from skin
Adipose connective tissue
What is an aponeurosis?
An aponeurosis is a thin, flattened sheet of dense regular connective tissue. It attaches muscle to either a skeletal component (bone or ligament) or to fascia
What is the function of satellite cells
Assist in repair of muscles
Why is skeletal muscle considered voluntary
Because the muscle fibers can be consciously controlled by the nervous system
What are the functions of skeletal muscle?
Body movement, maintenance of posture, protection and support, regulating elimination of materials, heat production
in a muscle there are concentric layer of connective tissue. from deep to superficial these connective tissue layers are the ______, the ______, and the _______
Endomysium, perimysium, Epimysium
What are the stages of cross-bridge cycling in order:
Calcium binds troponin; myosin binding site uncovered Cross bridge formation Power stroke Release of myosin head by ATP Reset of myosin head
What happens in the capillaries of skeletal muscles
Capillaries are the site of oxygen exchange, glucose exchange, and removal of wast products. Exchange occurs between blood and skeletal muscle fibers
The enzyme acetylcholinesterase resides in the synaptic ____
Cleft
What structures do the epimysium, perimysium, and endomysium form collectively
Collectively they extend past the muscle fibers to form either a tendon or an aponeurosis
What are myofibrils
Cylindrical organelles specialized for contraction
What type of connective tissue is the epimysium made of
Dense irregular connective tissue and is fibrous tissue
What contributes to the eventual total number of nuclei in the fiber
Each myoblast nucleus
What is elasticity
Elasticity is the ability of a muscle cell to return to its original length following either shortening or lengthening of the muscle
What is the elasticity of muscle cells dependent upon?
Elasticity of muscle cells is dependent upon the release of tension in the springlike connectin protein associated with contractile proteins
What is muscle fiber
Elongated, multinucleated cylindrical cell
What are the 3 layers of connective tissue within muscles
Epimysium-surrounds muscle Perimysium-surrounds the fascicle Endomysium-surrounds the muscle cell
When is extensibility exhibited
Extensibility is exhibited when we stretch our muscles before exercising
Slow muscle fibers are about ____ the diameter of fast muscle fibers.
Half
If a muscle cell is stimulated to contract, allowd to partially relax, then stimulated again, its force of contraction the second time will be ____
Higher
Why is a skeletal muscle an organ?
It is an organ because it is made of two or more types of tissue that work together to perform a specific function
What is the location of the deep fascia in relation to the superficial fascia
It is deep or internal to the superficial fascia
What is superficial fascia made of?
It is made of areolar connective tissue and adipose connective tissue
What is an axon?
Is also called a nerve fiber
What is the function of the epimysium
It's function is to protect and support the muscle to protect and support it like a tough leather sleeve
In order to predict how much tension a muscle can produce when contracting, it is important to consider the ____ relationship of thick and thin filaments
Length-tension relationship
Myofibril
Long cylindrical contractile element within muscle cell
What are the characteristics of glycolytic fibers
Low concentration of myoglobin White
although muscle fibers obey the all-or-none principle, the force of muscle contraction can be varied depending on how many ______ units are used
Motor
What controls skeletal muscle contraction
Motor neurons control skeletal muscle contraction
What nerves innervate skeletal muscles
Motor neurons of the somatic nervous system Somatic motor neurons extend from the brain and spinal cord to skeletal muscle fibers
What is a muscle
Multiple bundles housing many muscle fibers
Events of a nerve impule arriving at synaptic knob
Nerve impulse arrives at synaptic knob Ca2+ enters and binds synaptic vesicles ACh is released into synaptic cleft ACh bind receptors on the motor end plate
What is the name of the junction between the axon and the muscle fiber
Neuromuscular junction
What is the organization of a muscle
Muscle fibers Muscle fibers bundled within a fascicle Multiple fascicles Within fascicles each muscle fiber is surrounded by an endomysium Each fascicle is wrapped in perimysium Entire muscle is covered in epimysium
What is the function of the 3 layers of connective tissue within muscles
Protection and support attachment of the muscle to the skeleton or other structures within the body sites for distribution of blood vessels and nerves
As you struggle to twist open a jar, more motor units are called into action until you finally generate enough force to open it. This is an example of
Recruitment
The plasma membrane of a skeletal muscle fiber is called the ____
Sarcolemma
What law of thermodynamics is demonstrated when muscle tissue produces heat
Second law of thermodynamics
When does skeletal muscle cell respond
Skeletal muscle cell responds when its receptors bind neurotransmitter acetylcholine
Describe the gross anatomy of skeletal muscles
Skeletal muscle fibers, connective tissue layers, blood vessels
What are the circular muscle bands that contract and relax to regulate passage of material
Sphincters
The skeletal muscles arranged in layers along the walls of the abdominal cavity and the floor of the pelvic cavity perform what function
Support, contraction, protection
The enzyme acetylcholine is found in the _____
Synaptic knob
What does the adipose connective tissue in superficial fascia do
The adipose connective tissue in superficial fascia separates muscle from skin
What connective tissue layers do the blood vessels of skeletal muscles extend through
The blood vessels extend through the epimysium, the perimysium to reach the endomysium
What is the function of the endomysium
The endomysium functions to electrically insulate the muscle fibers
What type of connective tissue is the endomysium made of
The endomysium is made of areolar connective tissue
Where is the epimysium
The epimysium covers the entire skeletal muscle
What is extensibility?
The lengthening of a muscle cell Lengthening is possible because the contractile proteins slide past one another to decrease their degree of overlap
What type of connective tissue is the perimysium made of
The perimysium is a layer of dense irregular connective tissue and is fibrous connective tissue
Where is the perimysium
The perimysium is found around each fascicle
What is the function of the perimysium
The perimysium provides protection and support to each bundle of muscle fibers
What are the smallest blood vessels of muscle tissue and where are they found?
The smallest blood vessels are capillaries an are found in the endomysium
What does the stimulus trigger
The stimulus triggers the movement of ions across the plasma membrane of the excitable cell
What is the thin filament composed of?
This is composed of actin, tropomyosin, and troponin
How does a skeletal muscle fiber reach it's length
To reach it's length groups of embryonic muscle cells called myoblasts fuse to form single skeletal muscle fibers during development
Skeletal muscle has an extensive network of blood vessels which means it is what?
Vascularized
Isometric contraction means
a muscle contracts and Does Change length
Isotonic contraction means
a muscle contracts but Does Not Change length
What is fascia
a thin sheath of fibrous tissue enclosing a muscle or other organ
What is conductivity
ability to transmit an impulse involves an electrical signal that is propagated along the plasma membrane as voltage-gated channels open sequentially during an action potential
What are the causes of muscle fatigue
build up of intracellular Pi insufficient Ca2+ Na+ or K+ imbalances
What are the 2 types of isotonic contractions
concentric and eccentric
What are the organelle of skeletal muscle fibers
cytoplasm golgi apparatus ribosomes vesicles cytoplasm is the sarcoplasm multinucleated-many nuclei
What is deep fascia?
dense irregular connective tissue around muscle, also called visceral fascia or muscular fascia
If you strain to push on a wall that does not move, your muscles are in what type of contraction
isometric
What are the types of muscle contraction
isotonic and isometric
What is another name for muscle cells
muscle fibers
What is another name for muscle fibers
myofibers
What is the thick filament composed of
myosin
Thick and thin filaments maintain their ____ whether the muscle is relaxed or contracted
same length
What is the function of fascia
separates individual muscles, binds muscles together with similar functions,fills spaces between muscles, contains nerves, blood vessels, and lymph vessels
Myofilament
short contractile proteins of 2 types, thick and thin
What type of muscle forms the majority of the walls of the digestive tract
smooth
Where is the endomysium
surrounds each individual muscle fiber
A cord-like structure that attaches muscle to bone is a ___
tendon
What is an isometric contraction?
tension develops, but there is no change in the length of the muscle
What is the function of an axon
the axon conducts nerve impulses away from the cell body
What is an isotonic contraction?
the muscle shortens or lengthens while resisting a constant load
What is the double stranded regulatory protein
tropomyosin
What type of muscle is skeletal muscle?
voluntary muscle