Chapter 11

¡Supera tus tareas y exámenes ahora con Quizwiz!

T/F: Hodgkin disease is a lymphoid neoplasm

True

T/F: Leukemia is usually manifested by an elevated WBC

True

T/F: Polycythemia vera is a myeloid neoplasm

True

T/F: Spontaneous conversion to AML may occur with PV, CML, and ET

True

Leukemias are malignant proliferations of

WBC

what is neutropenia

absolute neutrophil count less than 500

the most appropriate action for thrombocytopenia is

activity restriction

Manifestations of ALL include

anema, leukocytosis, and thrombocytopenia

The philadelphia chromosome is a balanced chromo translocation that forms a new gene called

bcr-abl

Signs of PCM

bence jones protein in urine hypercalcemia

Prognosis of ALL

best prognosis. 90% remission if caught early

Predominant cell in AML

blasts

PCM: malignant plasma cells accumulate in

bone

location of malignancy in leukemia

bone marrow

Symptoms of ALL

bone pain, bruising, fever, infection, loss of appetite, enlarged spleen, liver, and lymph

ALL is primarily found in

children

CLL

chronic lymphocytic leukemia

Low grade forms of lymphoma generally have a poorer prognoses than high grade

false

T/F: plasma cell myeloma is a myeloid neoplasm

false. Lymphoid neoplasm

T/F: blasts are seen in CLL blood smear

false. NO BLASTS

T/F: if a myeloid leukemia infiltrates a lymph node it is considered a lymphoma

false: just considered myeloid infiltrate

CLL symptoms

fatigue, weight loss, anorexia increased susceptibility to infections enlarged lymph nodes and spleen

Characteristics of blasts

huge nucleus nucleoli no cytoplasmic differentiation

the most serious complication of chemo is

immunosuppression

The major cause of death from leukemic disease is

infection

Hematologic Neoplasms clinical manifestations

leukopenia, anema, thrombocytopenia

Signs of thrombocytopenia

low platelet count, petachiae, easy bruising, bleeding gums, retinal hemorrhages

location of malignancy in lymphoma

lymphoid tissues

ALL involves malignant transformation of

mostly B cells (80%)

Which cells are involved in myeloid neoplasms

neutrophils, monocytes, RBC, megakaryocyte

Myelodysplastic syndrome prognosis

poor

prognosis of CML

poor does not respond well to chemo

Fluid and diuretic therapy are used to manage PCM to

prevent damage to renal tubules

Blood smear of CML shows

smudge/basket appearance of cells

AML is associated with

transformation of myeloid stem cell (think I love lucy scene!)

T/F: Chemo is the main treatment for various types of leukemia

true

T/F: all lymphomas are malignant

true

Clinical manifestations of CLL

-malignant B-cell precursors - slow-growing & ASYMPTOMATIC

Prognosis

3 years. 60% remission rate

Prognosis of CML

8-24 years

the best prognosis for long term disease free survival occurs with

ALL

PCM involves what protein

Bence jones protein found in urine

Myeloproliferative diseases include

CML, Polycythemia vera, essential thrombocytopenia

Complete remission of leukemia

CR is less than 5% blasts in marrow and normal CBC values

Treatment of ALL

Chemo

Burkitt lymphoma is most closely associated with

Epstein-Barr virus

T/F: AML occurs in mostly children

False. mostly in adults

T/F: Non-Hodgkin lymphoma tends to spread in a predictable pattern

False. unpredicatble. hodgkin is predictable

Lymphomas are malignant proliferations of

Lymphocytes

Which cells are involved in lymphoid neoplasms

NK, B, and T

diagnosis of: generalized bone demineralization and compression fracture, elevated Ca levels

PCM

CML involves

Philadelphia chromosome and bcr/abl

T/F: immunoglobulins produced by malignant plasma cells are monoclonal

T


Conjuntos de estudio relacionados

Missed and Guessed Q's from Law of Promulgated Contracts

View Set

Property Casualty Exam - Quizzes

View Set

Chapter 4: Socioemotional Development in Infancy

View Set

Critical development geographies references

View Set

OSHA 30 - Module 1A: Introduction to OSHA and the OSH Act

View Set

Chapter 7: Management and Leadership

View Set