fibroblast
type V collagen
BM, BV, ligaments, skin, dentin, gingiva and PDL
gap junction
allows ions and small water soluble molecules to pass through
glycoprotein
bind cells to extracellular matrix ground substance help retain water in cell
type I collegen
bone, gingiva, connective tissue,skin
fibroblast secretory products
collagens elastins-found around blodo vessels and PDL proteoglycans- glycosaminoglycans glycoproteins- have adhesive properties
adhering
connect fibroblast to fibroblast or fibroblast to epithelium
predominant cells of connective tissue
fibroblast
fibroblast function
form fibers of connective tissue: (extracellular) collagen and elastin
type III collagen
found embryo connective tissue, pulp, PDL, skin
type II collagen
found in cartilage
microfilaments
have contractile protein actin and myosin-intercellular muscle: maintain shape of cell cytoplasmic movement and cell motility
osteogenesis imperfecta
mutation of type I collagen
tight occluding
prevent movement fo material between cells
two types of fibroblast
resting, flat, dark, closed nucleus with little cytoplasm active pale open nucleus with more cytoplasm (PDL)
marfan's syndrom
the 2nd most common inherited connective tissue disease elastin issue