fibroblast

type V collagen

BM, BV, ligaments, skin, dentin, gingiva and PDL

gap junction

allows ions and small water soluble molecules to pass through

glycoprotein

bind cells to extracellular matrix ground substance help retain water in cell

type I collegen

bone, gingiva, connective tissue,skin

fibroblast secretory products

collagens elastins-found around blodo vessels and PDL proteoglycans- glycosaminoglycans glycoproteins- have adhesive properties

adhering

connect fibroblast to fibroblast or fibroblast to epithelium

predominant cells of connective tissue

fibroblast

fibroblast function

form fibers of connective tissue: (extracellular) collagen and elastin

type III collagen

found embryo connective tissue, pulp, PDL, skin

type II collagen

found in cartilage

microfilaments

have contractile protein actin and myosin-intercellular muscle: maintain shape of cell cytoplasmic movement and cell motility

osteogenesis imperfecta

mutation of type I collagen

tight occluding

prevent movement fo material between cells

two types of fibroblast

resting, flat, dark, closed nucleus with little cytoplasm active pale open nucleus with more cytoplasm (PDL)

marfan's syndrom

the 2nd most common inherited connective tissue disease elastin issue