Funeral Pathology FINAL Study Guide (FSE2160)

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Primary difference between Hodgkin and Non-Hodgkin lymphoma:

*Hodgkin lymphoma*is marked by the presence of *Reed-Sternberg cells*. In non-Hodgkin lymphoma, these cells are not present.

Valvular Defects of the heart:

*Insufficiency* (incompetence) - incomplete closure of valves *Stenosis* - narrowing or constriction *Prolapse* - falling or dropping of an organ/part

Process of Inflammation (both vascular and cellular)

*Vasodilation* - greater blood flow to the area = redness and heat. *Vascular permeability* - endothelial cells spread apart *Exudation* - fluids escape from the intravascular space *Vascular stasis* - slowing of the blood allows chemical mediators and inflammatory cells to collect and respond to the stimulus.

Characteristics of Acute and Chronic bronchitis:

-*Acute* bronchitis usually follows a respiratory infection -*Chronic* bronchitis is a long-term disorder of the bronchi -Both acute and chronic forms are accompanied by excessive mucus production

Inflammatory/degenerative diseases related to the integumentary system

-Acne -Abscess -Syphilis -Superficial fungal infections -Seborrheic dermatitis -Eczema

Types of acute inflammation of the respiratory tract:

-Acute Coryza -Rhinitis -Sinusitis -Hay fever -Pharyngitis -Laryngitis -Influenza

Diseases related to the adrenal gland:

-Addison's Disease -Cushing's Disease -Waterhouse-Friderichsen Syndrome

Benign neoplasms of Epithelial tissue

-Adenoma -Papilloma -Polyp -Nevus (pigmented mole)

Predisposing conditions for disease

-Age -Race -Nutrition -Gender -Occupation -Environment -Emotional -Economic status -Heredity

Generalized Hyperemia may result in:

-Anoxemia - insufficient blood oxygen -Dyspnea - labored breathing (result of anoxemia) -Cyanosis - Bluish skin due to low oxygen

The importance of autopsy as a tool in the advancement of medical science to:

-Confirm medical diagnosis -Advance medical knowledge and research -Assist in medico-legal cases

Embalming complications associated with edema

-Diminished circulation -abscesses -hemorrhage -edema -rapid decomp -discolorations -emaciation/dehydration

Postmortem conditions related to the integumentary system:

-Discolorations -Dehydration/dryness/scales -Burns -Lesions -Pigmented or depigmented spots -Edema

Postmortem conditions related to diseases of the endocrine system:

-Edema -Discoloration -Deformities -Interference of Circulation

Postmortem conditions related to the lymphatic system:

-Edema -Emaciation -Dehydration -Metastasis -Swelling

Embalming complications associated with Neoplasms:

-Emaciation -Dehydration -Cachexia -Discoloration -Hemorrhage -Tissue deformation -Extravascular obstruction

Hyperplastic/Neoplastic disorders of the female reproductive system:

-Endometriosis -Polycystic Ovaries -Dermoid Cysts -Cervical Cancer -Breast Cancer

Defensive barriers: Extrinsic

-Environmental Conditions -General Health of the host (exercise, nutrition, etc)

Localized Causes of Hyperemia

-Formation of blood clots -Thickening of vessel walls -Pressure from lesion

Causes of Embolism

-Fragments of thrombi -Bacteria -Tumor cells -Animal parasites -Fat -Gas -Foreign bodies

Defensive barriers: Chemical

-Gastric juices -Antibodies -Interferon (Antiviral protein) -Lysozyme (Enzyme that destroys invading microbes)

Characteristics of *Benign* tumors

-Grow by expansion -Encapsulated -Do not migrate (do not metastasize) -Do not cause extensive tissue damage -Resemble tissue from which they originated -Generally do not return after surgical removal -Generally are not fatal

Characteristics of *Malignant* tumors

-Grow by infiltration -Non-encapsulated -Metastasize, creating secondary foci -cause extensive tissue damage -Tumor does not resemble tissue surrounding it -Can reoccur when surgically removed -Lethal unless treated

Signs and Symptoms of Inflammation

-Heat -Redness -Swelling -Pain -Altered function -Pyrexia

Hemophilia

-Hereditary disorder caused by a defective x-chromosome -it can be passed on to female offspring by the mother or father -it can be passed on to male offspring by the mother. -males are more likely to have the disorder than females -victims have an abnormal tendency to bleed

Predisposing factors to heart disease

-Heredity -Obesity -Diabetes -Elevated cholesterol levels -Social factors (smoking, drugs, stress, diet)

Causes of Edema

-Increased permeability of capillary walls -Increased capillary pressure due to heart failure -Inflammatory conditions -Venous or lymphatic obstruction

Causes of Thrombosis

-Injuries to blood vessels -Reduced rate of blood flow -Blood diseases -Alterations in blood composition -Eddies (swirls) in blood

Defensive barriers: Mechanical

-Intact Skin -Intact mucous membranes -Bony encasements (i.e. skull, ribcage) -Stationary cilia (i.e. nose hairs) -Anastomosis (branching of blood vessels in case of blockage)

Consequences of an embolism

-Ischemia -Infarction or gangrene -Spread of infection -Spread of tumors -Necrosis

Hematopoietic Disorders

-Leukocytosis -Leukemia -Leukopenia -Polycythemia Vera -Erythrocytosis

Postmortem condition related to skeletal diseases:

-Malformations -Bone Procurement -Broken bones

Causes of Ischemia (reduction of blood supply)

-Obstruction by a thrombus or embolus -External pressure -Thickening of vessel walls -Drugs

Diseases associated with the male reproductive system:

-Orchitis -Cryptorchism -Testicular carcinoma -Epididymitis

Types of thrombi

-Parietal - adhering to one side of the vessel wall -Obstructive - obstructs the vessel -Septic - clot that is infected with bacteria

Types of Primary Anemia

-Pernicious anemia -Aplastic anemia -Chlorotic anemia

Defensive barriers: Physiological

-Phagocytosis (ingestion of bacteria by phagocytes) -Inflammation -Fever -Flowing body fluids -Oscillating cilia -Reflex actions (i.e. Sneezing; coughing, etc)

Causes of inflammation

-Physical irritants -Chemical irritants -Infectious agents -Immunological reactions

Postmortem conditions associated with the female reproductive system:

-Rapid Blood Coagulation -Ascites -Edema -Infection

Types of Secondary (hemolytic) Anemia

-Sickle-cell anemia -Erythroblastosis anemia

Inflammatory diseases of the lymphatic system:

-Tonsillitis -Lymphangitis -Splenomegaly -Lymphedema

Causes of Hemorrhage

-Trauma -Diseases of blood vessels -Hypertension -Disease of the blood

causes of necrosis

-Trauma -Interference with Blood supply -Extreme Temperatures -Chemical agents -Loss of nerve supply

Characteristics of Neoplasms (tumors)

-abnormal growth of tissue -serves no useful purpose in the body -sometimes characterized as malignant -sometimes characterized as benign

Postmortem conditions associated with trauma to the nervous system:

-brain purge -hemorrhage -atrophy -diminished circulation

Postmortem conditions associated with tuberculosis:

-cavitation -hemorrhage -dehydration -emaciation -cold abscess

Postmortem conditions associated with diseases of the urinary system:

-edema -uremia -icterus -odor -dehydration

Types of intracranial hemorrhage

-extradural hemorrhage -subdural hemorrhage -subarachnoid hemorrhage

Causes of tumors

-heredity -environmental factors/exposures -occupational exposure -prolonged irritation -viruses -hormones -Idiopathic (of unknown cause)

Embalming complications associated with blood diseases

-intravascular resistance -diseased vessels can rupture -blood clots -increased blood viscosity

Malignant neoplasms of Epithelial tissue

-melanoma -squamous cell carcinoma -adenocarcinoma. -transitional cell carcinoma -basal cell carcinoma

Benign Neoplasms of Connective tissue

-osteoma -chondroma -lipoma -angioma -fibroma

Malignant Neoplasms of Connective tissue

-osteosarcoma -chondrosarcoma -liposarcoma -angiosarcoma -fibrosarcoma -lymphoma (lymphosarcoma)

Functions of inflammation

-protection from foreign organisms -removal of dead and necrotic tissues -repair of tissue trauma

Postmortem conditions associated with pneumonia:

-rapid coagulation of blood -cyanosis -dehydration -edema

Thrombi can be found in these locations:

-veins -heart -coronary arteries

Three stages of pyrexia:

1. Invasion - when pyrexia first appears 2. Fastigium - the height of the pyrexia 3. Defervescence - the lessening of the pyrexia

Inflamed area of pus walled off by a membrane

Abscess

A genetic defect which causes a person to develop improperly in the formation at the epiphysis (middle, bone-forming center of bones) and produces a form of dwarfism

Achondroplasia

A disease, condition or abnormality that is not hereditary or innate

Acquired

Hyperfunction of the anterior lobe of the pituitary gland. Causes abnormal growth of bones of the extremities and certain head bones, due to overproduction of human growth hormone

Acromegaly

Increased arterial blood supply to an organ for physiologic reasons

Active hyperemia (physiological)

A disease with rapid onset and short duration

Acute

Condition in which the adrenal glands fail to produce enough cortisol or aldosterone.

Addison's Disease

Having a hypersensitive immune response to a foreign substance

Allergies

Progressively destructive neurologic disorder that causes dementia and changes in the brain over 10-15 years

Alzheimer's Disease

Congenital absence of one or more limbs

Amelia

Generalized edema in subcutaneous tissue

Anasarca

Severe generalized edema

Anasarca

A decrease in the number of red blood cells and/or hemoglobin in the blood

Anemia

Localized dilation or ballooning of an artery

Aneurysm

Failure of a tissue or an organ to develop normally

Aplasia

The middle layer of the meninges

Arachnoid mater

Artery walls become thickened and less flexible. Loss of elasticity may occur in Tunica Media and/or Tunica Intima

Arteriosclerosis

Inflammation of an artery

Arteritis

A condition caused by inhalation of asbestos

Asbestosis

Accumulation of fluid in the abdomen

Ascites

Plaque buildup on vessel lining, which reduces lumen and blood supply. Most common form of arteriosclerosis

Atherosclerosis

Tinea pedis is also known as:

Athlete's foot

A wasting; decrease in size of an organ or tissue

Atrophy

Restriction of the bronchial tubes:

Bronchial asthma

Inflammation of the mucus membrane of bronchi

Bronchitis

Pneumonia that causes inflammation in the alveoli

Bronchopneumonia

Inflammation of the bursa, usually caused by overuse of the joint

Bursitis

A condition caused by inhalation of cotton dust; also called brown lung disease:

Byssinosis

Boils of the skin and subcutaneous tissues with production and discharge of pus

Carbuncle

Disease of the heart muscle

Cardiomyopathy

Inflammation of the heart, involving at least two of the following: endocardium, pericardium, myocardium

Carditis

Form of cell death in which the tissue appears as a soft and white proteinaceous dead cell mass. Often caused by Tuberculosis.

Caseous necrosis

Disorder which results from developmental anomalies or brain injury during late pregnancy or early childhood

Cerebral Palsy

Rupture or blockage of a vessel in the brain

Cerebrovascular Accident (Stroke)

A condition caused by exposure to copper dust

Chalcosis

A condition caused by inhalation of marble or limestone dust

Chalicosis

Addition of chemical into the body to treat a generalized cancer (cancer that may be throughout the entire body)

Chemotherapy

Inflammation of the biliary duct

Cholangitis

Inflammation of the gall bladder

Cholecystitis

A disease with a slow onset and long duration

Chronic

A scar left by a healed wound

Cicatrix (repaired tissue)

A fissure in the palate and of the upper lip

Clef Palate and Lip

Study of disease performed in a laboratory by means of examining body fluids, secretions, and excretions

Clinical pathology

Inflammation of the colon

Colonitis

Type of fracture in which the bone breaks into small pieces

Comminuted fracture

Type of fracture in which the line of fracture is all the way across the width of the bone

Complete fracture

An unfavorable condition arising during the course of disease

Complication

Type of fracture where the skin is broken, bone protrudes from wound

Compound fracture

The immediate and temporary disturbance of brain function as a result of trauma

Concussion

Existing at the time of birth or shortly thereafter

Congenital

A problem with heart structure/function, present at birth

Congenital Heart Disease

*Chronic* cardiac failure - a weakness of the heart that leads to a buildup of fluid in the lungs and surrounding body tissues

Congestive Heart Failure

Disease that may be transmitted directly or indirectly between individuals by an infectious agent

Contagious (communicable)

A bruise, often accompanied by swelling.

Contusion

A narrowing of the coronary arteries

Coronary Artery Disease

A condition that is similar to dwarfism, except it also includes a decrease in the mental capacity of the individual.

Cretinism

Spongiform encephalopathy characterized by holes in the brain. Caused by a prion; can be contracted through contact with spinal fluid of the deceased

Creutzfeldt-Jakob Disease

An iatrogenic disorder of the adrenal glands due to chronic glucocorticoid hormone therapy

Cushing's Disease

Inflammation of the urinary bladder

Cystitis

A condition due to lack of dietary or metabolic substance

Deficiency

The deterioration of tissues with corresponding functional impairment as a result of disease or injury

Degeneration

Condition caused by a disorder between the pituitary gland and kidneys, resulting in kidneys unable to conserve water. Leads to excessive thirst and urination.

Diabetes Insipidus

Denotes the identification of a disease or syndrome; to recognize the nature of a disease

Diagnosis

Abnormal increase in size of cavities of the heart

Dilation

A rupture in the intima, the innermost coat of an artery, that permits blood to enter between the wall of the the artery and causes separation of the layers of the wall.

Dissecting Aneurism

A condition in which small, bulging pouches develop in the digestive tract.

Diverticulosis

A congenital disorder arising from a chromosome defect, causing intellectual impairment and physical abnormalities

Downs Syndrome

A form of necrosis that occurs when tissues become dehydrated due to reduction in blood supply.

Dry gangrene (ischemic necrosis)

The outermost layer of the meninges

Dura mater

Condition in which the pituitary gland fails to secrete enough growth hormone in childhood.

Dwarfism

A discoloration of the skin resulting from bleeding underneath, typically caused by bruising

Ecchymosis

Abnormal accumulation of fluids in tissue or body cavities

Edema

The sudden obstruction of a blood vessel by debris

Embolism

Inflammation of the brain

Encephalitis

A disease that is continuously present in a given population

Endemic

Inflammation of the lining of the heart, or heart valves

Endocarditis

Inflammation of the inner lining of the uterus

Endometritis

A hyperemic condition in the lungs is known as:

Engorgement

Higher than normal appearance of an infectious disease/condition in a given population

Epidemic

Bleeding from the nose:

Epistaxis

The Study of the Cause of Disease

Etiology

Increase in severity of a disease

Exacerbation

Blood pools outside the meninges; between the dura mater and the skull

Extradural hemmorhage

Any fluid released from the body with a high concentration of protein, cells, or solid debris

Exudates

Pertaining to or characterized by fever

Febrile

An abnormal or surgically made passage between a hollow or tubular organ.

Fistula

Having rapid and severe onset, usually fatal

Fulminating

A disease which has no recognizable change in anatomy

Functional disease

Abscess due to a pyogenic infection of a sweat gland or hair follicle

Furuncle

A form of aneurism that bulges on all sides of the affected vessel.

Fusiform

Deals with the study of general processes of disease such as inflammation, degeneration, necrosis or cellular death, repair, etc., without reference to particular organs or organ systems.

General pathology

Condition in which the pituitary gland produces an excess amount of growth hormone beginning in childhood

Gigantism

Neoplasm of Nervous tissue

Glioma

Microbial inflammation of the glomerulus and nephron

Glomerulonephritis

Excessive growth of the thyroid gland due to a lack of iodine in the diet

Goiter

Condition resulting from the buildup of uric acid in the blood and leading to the formation of urate crystals in and around joints; a hereditary metabolic disorder.

Gouty arthritis

Usually caused by epilepsy, this type of seizure causes a loss of consciousness and violent muscle contractions:

Grand mal seizure

Type of hyperthyroidism caused by an autoimmune attack on the thyroid gland. Leading cause of an overactive thyroid gland; effects women 7 times more often than men.

Grave's Disease

Type of fracture in which the line of fracture does not include the whole bone

Greenstick fracture

Study of changes in the structure of the body as a result of disease that are readily seen with the naked eye

Gross pathology

An autoimmune disease that damages the thyroid gland. Affects more women than men; it's the most common cause of hypothyroidism

Hashimoto's Thyroiditis

Vomiting blood

Hematemesis

Swelling of blood confined to one area, caused by ruptured vessel.

Hematoma

Red blood cells in urine

Hematuria

Coughing up red frothy blood in the sputum from respiratory tract:

Hemoptysis

Seepage of blood through intact capillaries

Hemorrhage per diapedesis

Rupture of the heart or wall of a vessel

Hemorrhage per rhexis

Exudates which contain blood

Hemorrhagic

Blood between the chest cavity and lungs

Hemothorax

Genetic characteristics transmitted from parent to offspring

Hereditary

The increase in the quantity of plasma in the body, therefore resulting in an increase in the total quantity of blood.

Hydremic plethora

Edema of the scrotum

Hydrocele

A condition in which cerebrospinal fluid fails to drain, causing the brain ventricles to fill with fluid:

Hydrocephalus

Excessive cerebrospinal fluid in ventricles of the brain

Hydrocephalus

Distention of the renal pelvis with urine as a result of obstruction

Hydronephrosis

Edema of the pericardial sac around the heart

Hydropericardium

Accumulation of fluid in the pleural (thoracic) cavity

Hydrothorax

An increased flow of blood to an area of the body

Hyperemia (a.k.a. Congestion)

Condition in which the parathyroid glands overproduce hormones

Hyperparathyroidism

Overdevelopment of a body part

Hyperplasia

Disease in which the heart must work harder in people with high blood pressure

Hypertensive Heart Disease

The enlargement of an organ or structure due to the increase in size of cells composing it

Hypertrophy

Condition in which the parathyroid glands underproduce hormones

Hypoparathyroidism

Incomplete development of a body part

Hypoplasia

Underdevelopment of a tissue, organ or the body

Hypoplasia

Any injury or illness that occurs as a result of medical care

Iatrogenic

A patient treated for an infection developing a severe allergic reaction to the antibiotics administered would be an example of which of the following?

Iatrogenic disorder

Of unknown cause

Idiopathic

A body with empyema (pus in the pleural cavity) will require____________during embalming.

Increased cavity care

Likely to be transmitted to people, organisms, etc., through the environment.

Infectious

The presence in or on the body of macroscopic organisms

Infestation

The passage and accumulation of a substance into cells, tissues, or organ

Infiltration

A tissue reaction to irritation, infection, or injury marked by localized heat, swelling, redness, pain and sometimes loss of function

Inflammation

Meningitis is caused by:

Inflammation of the membranes that cover the brain and spinal cord

A projection of the intestine through the inguinal area:

Inguinal hernia

The state of being poisoned by a drug or toxic substance

Intoxication

An obstruction of the hepatic duct can cause:

Jaundice

Tinea Crura is also known as:

Jock itch

Abnormal outward curve of the spine

Kyphosis

A circumscribed area of pathologically altered tissue; an injury or wound

Lesion

An increase in white blood cells, usually as an inflammatory response:

Leukocytosis

A decrease in white blood cells

Leukopenia

Abnormal anterior curvature of the spine

Lordosis

Swelling in an arm or leg caused by a lymphatic system blockage

Lymphedema

Study of disease to ascertain cause and manner of death, as related to a criminal investigation

Medico-legal Pathology (Forensic Pathology)

Black tarry feces usually from stomach bleeding

Melena

The change of tissue from one form to another (i.e. a scar forming)

Metaplasia

Study of microscopic changes that cells, tissues and organs undergo as a result of disease

Microscopic pathology (a.k.a. histopathology/cellular pathology/histology)

A form of tuberculosis that spreads throughout the body

Miliary Tuberculosis

The rate of *illness* in a given population

Morbidity rate

The rate of *death* in a given population

Mortality rate

Autoimmune disease which causes the myelin sheaths of the nerve cells to be damaged

Multiple sclerosis

*Acute* cardiac failure - one or both coronary arteries become occuluded

Myocardial Infarction

Inflammation of the heart muscle

Myocarditis

Benign Neoplasms of Muscle tissue

Myoma (includes rhabdomyoma and Leiomyoma)

Malignant Neoplasms of Muscle tissue

Myosarcoma (includes Rhabdomyosarcoma and leiomyosarcoma)

Form of severe hypothyroidism; gives the skin a waxy or coarsened appearance

Myxedema

Pathological death of cells, tissues and organs while still a part of the living organism

Necrosis

A degenerative disease of the kidneys

Nephrosis

Any non-inflammatory degenerative condition of the kidney

Nephrosis

Benign Neoplasm of Nervous tissue

Neuroma

Infection acquired in a healthcare setting

Nosocomial

A disease related to one's working conditions

Occupational

Inflammation of the ovary

Oophoritis

A disease which creates any structural/anatomical change for the normal human body

Organic disease

Degenerative joint disease; caused by deterioration of joint cartilage

Osteoarthritis

Softening of bones, caused by insufficient vitamin D consumption/production

Osteomalacia (Rickets)

Inflammation of the bone marrow

Osteomyelitis

Loss of bone density, resulting in bone weakness

Osteoporosis

Malignant neoplasm of bone

Osteosarcoma

A chronic, degenerative nervous system disorder, characterized by tremors, muscle weakness, and a peculiar gait:

Parkinson's Disease

A blocked vein, or engorgement of an organ/tissue with blood due to inadequate venous drainage

Passive hyperemia (pathological)

The origin and development of a disease

Pathogenesis

Study of *structural* changes in the body caused by disease

Pathological Anatomy (a.k.a. Morbid Anatomy)

Hyperemia that is related to inflammatory processes

Pathological hyperemia

Inflammation of the tissues surrounding the heart

Pericarditis

A decrease in red blood cells, due to vitamin B deficiency

Pernicious anemia

Small pinpoint hemorrhages visible on the skin

Petechia

Rapidly spreading destructive ulceration of soft tissue.

Phagedena

Inflammation of a vein

Phlebitis

Inflammation of soft tissue that spreads under the skin or inside the body

Phlegmon

Congenital condition in which the proximal portions of the limbs are poorly developed or absent

Phocomelia

When Ernest returns home late after an evening of smoking cigars, drinking beer, and playing poker with the boys, his wife clobbers him over the head with a frying pan, causing a bump to form on his scalp. The bump on Earnest's head is an example of inflammation caused by:

Physical irritants

Study of *functional* changes in the body caused by disease

Physiological Pathology

Hyperemia that occurs due to increased blood demand during exercise, etc

Physiological hyperemia

The innermost layer of the meninges

Pia mater

Edema usually in the skin of the extremities. When pressed with a finger, the fingerprint leaves a depression.

Pitting edema

The master gland of the body

Pituitary gland

A disease of the lungs due to inhalation of dust

Pneumoconiosis

Abnormally increased concentration of hemoglobin in the blood

Polycythemia

Birth defect in which one is born with extra fingers or toes

Polydactylism

Increased thirst

Polydipsia

Excessive or an abnormally large production or passage of urine

Polyuria

Number of cases of disease present in a specified population at a given time

Prevalence

Inflammation of the rectum

Proctitis

Prediction of the outcome of a disease

Prognosis

A form of tuberculosis in which only the lungs are affected:

Pulmonary tuberculosis

This disorder is characterized by the appearance of purple patches on the skin

Purpura

Exudates primarily composed of pus resulting from infections

Purulent

Small elevation of the skin containing pus

Pustule

Inflammation of the renal pelvis of the kidney

Pyelitis

Inflammation of the kidney and nephron

Pyelonephritis

An accumulation of pus in the fallopian tube:

Pyosalpinx

A rise in the temperature of the body; frequently a symptom of infection:

Pyrexia

The presence of pus in the urine

Pyuria

Neurotropic infectious disease of warm-blooded animals

Rabies

Treatment used for localized cancer. Since the use of this treatment results in the death of all tissue around the affected area, physicians seek to treat only small areas using this method:

Radiation

Reappearance of symptoms after a period of remission

Recurrent

A cessation of the symptoms of disease

Remission

Usually caused by rheumatic fever, valves of the heart becomes scarred and thickened, leading to stenosis and insufficiency:

Rheumatic Heart Disease

Inflammation of the lining of the joints; result of an autoimmune attack on the synovium

Rheumatoid Arthritis

A form of aneurism that bulges only to one side of a vessel

Saccular

Abnormal lateral curvature of the spine

Scoliosis

Exudates which contain plasma, are rich in proteins and white blood cells

Serous

A condition caused by inhalation of iron dust

Siderosis

*Objective* indications of the presence of disease (can be observed by other people - i.e., swelling)

Signs

Deficiency of function of the pituitary gland, a form of hypopituitarism that leads to atrophy of many of the viscera, including the heart, liver, spleen, kidneys, thyroid, adrenals, and gonads

Simmonds' Disease

Type of fracture in which the skin is not broken

Simple fracture

Deals with the specific features of disease in relation to particular organs or organ systems.

Special pathology

Congenital defect in which part of the vertebral column is absent or there is incomplete closure

Spina bifida

Disease that occurs in a random or isolated manner

Sporadic

Inflammation of the mouth

Stomatitis

Study of tissue specimens excised surgically in an operation

Surgical Pathology

*Subjective* indications of the presence of disease (felt/experienced only by the patient - i.e., headache)

Symptoms

This reproductive disorder is characterized by hard chancres on the genitalia and very contagious

Syphilis

Belief that every disease in the body begins at the cellular level

The Doctrine of Cellular Pathology (Virchow)

The formation or presence of an attached blood clot (thrombus), most commonly found in *veins*

Thrombosis

A thrombus that has broken off and is moving throughout the vascular system.

Thrombotic Embolus

A fungal infection spread among people when the barber uses scissors or instruments that have been contaminated.

Tinea Capita

Inflammation of the trachea

Tracheitis

Temporary, insufficient oxygen supply to the brain

Transient Ischemic Attack

Syphilis is caused by

Treponema pallidum

The scientific term for swelling:

Tumor

Insulin-dependent diabetes mellitus

Type 1

Non-insulin dependent diabetes mellitus

Type 2

Open sore or lesion accompanied by sloughing of inflamed necrotic tissue

Ulcer

Condition caused by retention in the blood of waste products normally excreted in the urine. Kidney failure leads to dangerous levels of urea in the blood.

Uremia

Enlarged veins in the lower extremities; a stagnation of blood.

Varicose veins

Birth mark, usually purplish in color

Vascular Nevus

Blister-like elevation of skin containing serous fluid

Vesicle

Any pneumonia which is caused by a virus.

Viral pneumonia

A form of liquefactive necrosis that results from bacterial or fungal infections developing in areas of dead tissue.

Wet gangrene

Pandemic

Widespread epidemic, possibly worldwide

Puerperal sepsis is also known as:

childbed fever, childbirth fever

An example of a Transient Ischemic Attack:

fainting

Down's Syndrome is a congenital condition caused by:

having three copies of chromosome 21

Inflammation of the ileum

ileitis

Inflammation of the gray matter in the spinal cord as a result of a viral infection

poliomyelitis


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