Hemoglobin Function

¡Supera tus tareas y exámenes ahora con Quizwiz!

Globin Portion

Consisits of amino acids linked together to form a polypeptide chain. Synthesized in the Ribosomes.

OD shift to the left

Hemoglobin has a higher attraction and affinity for oxygen. Decrease in 2,3-DPG, reduced body temperatures, and alkalosis.

Heme Portion

Involves four iron atoms in the ferrous state (Fe2+). Surronded by the protoporphyrin ring (structure formed in the nucleated red blood cells). Synthesized in the mitochondria.

Hemoglobin

Life giving substance of every blood cell, the oxygen carrying component of the red blood cell. A protein, the main cytoplasmic component of the erythrocyte. Picks up oxygen from the lungs and releases it in the tissues.

OD shift to the right

More likely to release oxygen to the tissues. Lower affinity, anemia, acidosis, Increased CO2 levels, and higher body temperature.

2,3-Diphosphoglycerate (2,3-DPG)

Produced via the Embden-meyerhof pathway during anaerobic glycolysis. Intimatly related to oxygen affinity of hemoglobin.

Oxygen Dissasociaton Curve

Represents oxygen release from hemoglobin to the tissues.

Allosteric Changes

The way hemoglobin is able to rotate on its axis, determine the action of salt bridges between the globin structures, and dictate the movement of 2,3-DPG. Has two forms tense and relaxed.


Conjuntos de estudio relacionados

Databases and SQL for Data Science with Python #ditkhitacontre

View Set

FARMACOLOGIA II LAB: Plantas para hacer tinturas y pomadas

View Set

APES Chapter 13 AP review questions

View Set

Topic 3 : Linear Equations and Inequalities in One Variable (Straighterline)

View Set

Econ principles #5 homework (study for Exam #2)

View Set

COMM 100 Chapter 1-What is Communication?

View Set

Principles, Philosophies, and People that influenced the American Government

View Set

PrepU Assignment | Chapter 44 | Assessment and Management of Patients with Biliary Disorders

View Set

ECO231: Exam 1 (Quizzes for Ch 1 - *half of* Ch 5)

View Set