Human Growth Hormone EXAM 2
Not ergogenic in those who are not GH deficient
***when they use a prescribed amount, but when they use more than they should, there is a performance benefit//super physiologic
How exercise effects HGH
1. exercise STIMULATES endogenous HGH output in both men and women 2. aerobically and anaerobically 3. is it related to intensity of activity? 4. HGH is attenuated by age and level of activity even through GH levels do spike (post exercise) in elderly men and women who use contraceptives
Avoiding potential complications
1. long term effects of HGH administration are not reversible (acromegaly) 2. needle sharing risk (infection/skin scarring) 3. bad batches of synthetic HGH
human growth hormone
1. polypeptide hormone that stimulates regeneration and growth and cell reproduction 2. amino acid which is anabolic in nature 3. secreted from the anterior pituitary gland 4. used in smaller amounts in season and larger doses when they can't/wont be tested 5. most highly sought drug among athletes enlarges people; it wasn't designed for people
What happens In HGH if abused?
1. somatotrop adenomas (benign tumors) that may grow in and around the brain (headache, blurred vision, etc) 2. Acromegaly 3. pituitary gigantism
So why do athletes use tis stuff...?
1. tissue repair 2. protein synthesis 3. anecdotal reports 4. possible increase effectiveness when used in combination
___ amino acids found in HGH
191
HGH is both ___ and ___
aerobic and anaerobic
HGH is secreted by
anterior pituitary gland
Long term effects of HGH adminsitrion are ___ reversible (acromegaly)
not
a ___ hormone that stimulates ___ and ___ and cell ______
polypeptide; regeneration, growth, and cell reproduction
hgh is "attenuated" (reduced) by age and level of activity ALTHOUGH GH levels spike (___ exercise) for ___ men and women who use ____
post; elderly, contraceptives
HGH increases ___ synthesis
protein
Pituitary gigantism
rare, but results from a GH secreting tumor in childnre
Somatotropin
somatropin; human growth hormone
Acromegaly
thickened jawbone, forehead, fingers and toes
Exogenous GH administration to those who are deficient has been associated with improvement in exercise performance. This causes increased muscle mass and muscle strength.
true
Initially ____ through standard urine screen drug tests
undetectable
NCAA and USCO status on GH
banned; testing, but they wont do blood tests so they cant find it. NFL, NHL, and MLB are currently testing for HGH -they have a union so no one is going to try and open us a lawsuit on you--it will become an issue because more people are using it especially where strength and power are needed in
Somatotrop adenomas
benign tumors that may grow in an around the brain
can be detected through ___ ____
blood draws
HGH decreases ___ ___
body fat; body fat is 8% and now its 3%-thats not normal or just good nutrition
HGH stimulates the growth of all internal organs excluding the ___
brain
Dwarfism
can be corrected supplementary HGH
GH supplementation ___ ___improve the msucualr strength on non deficient endogenous GH power lifters
does not
GH
growth hormone
Originally intended for the use in children who suffer from ___ disorders and ___ who were not endogenously producing enough GH (dwarfism)
growth; adults
HGH related to intensity?
helps those who are deficient but not really sure about the rest of people
HGH plays a rome in ___
homeostatsis
HGH Increases muscle mass through sarcomere ____ (speed-how fast it can regenerate)
hyperplasia
HGH causes _____ - increased amounts of ___ lead to Increased protein synthesis - GH effects on muscle persist and do not wear off like the effects of anabolic steroids -endogenous levels that are elevated cause ____
hyperplasia; RNA; acromegaly
Anabolic steroids cause ____
hypertrophy; cut bicep across the fibers, exercise, cross-sectional thickness will improve
Why athletes use HGH? 1. increased ___ ___ and streghtens and increases ____ of ____
increased calcium retention; mineralization of bone
HGH promotes
lipolysis
HGH reduces ___ reuptake of glucose
liver
exercise stimulates endogenous HGH output in both ___ and ____
men and women
HGH is the ___ highly sought drug among athletes
most