Human Growth Hormone EXAM 2

Not ergogenic in those who are not GH deficient

***when they use a prescribed amount, but when they use more than they should, there is a performance benefit//super physiologic

How exercise effects HGH

1. exercise STIMULATES endogenous HGH output in both men and women 2. aerobically and anaerobically 3. is it related to intensity of activity? 4. HGH is attenuated by age and level of activity even through GH levels do spike (post exercise) in elderly men and women who use contraceptives

Avoiding potential complications

1. long term effects of HGH administration are not reversible (acromegaly) 2. needle sharing risk (infection/skin scarring) 3. bad batches of synthetic HGH

human growth hormone

1. polypeptide hormone that stimulates regeneration and growth and cell reproduction 2. amino acid which is anabolic in nature 3. secreted from the anterior pituitary gland 4. used in smaller amounts in season and larger doses when they can't/wont be tested 5. most highly sought drug among athletes enlarges people; it wasn't designed for people

What happens In HGH if abused?

1. somatotrop adenomas (benign tumors) that may grow in and around the brain (headache, blurred vision, etc) 2. Acromegaly 3. pituitary gigantism

So why do athletes use tis stuff...?

1. tissue repair 2. protein synthesis 3. anecdotal reports 4. possible increase effectiveness when used in combination

___ amino acids found in HGH

191

HGH is both ___ and ___

aerobic and anaerobic

HGH is secreted by

anterior pituitary gland

Long term effects of HGH adminsitrion are ___ reversible (acromegaly)

not

a ___ hormone that stimulates ___ and ___ and cell ______

polypeptide; regeneration, growth, and cell reproduction

hgh is "attenuated" (reduced) by age and level of activity ALTHOUGH GH levels spike (___ exercise) for ___ men and women who use ____

post; elderly, contraceptives

HGH increases ___ synthesis

protein

Pituitary gigantism

rare, but results from a GH secreting tumor in childnre

Somatotropin

somatropin; human growth hormone

Acromegaly

thickened jawbone, forehead, fingers and toes

Exogenous GH administration to those who are deficient has been associated with improvement in exercise performance. This causes increased muscle mass and muscle strength.

true

Initially ____ through standard urine screen drug tests

undetectable

NCAA and USCO status on GH

banned; testing, but they wont do blood tests so they cant find it. NFL, NHL, and MLB are currently testing for HGH -they have a union so no one is going to try and open us a lawsuit on you--it will become an issue because more people are using it especially where strength and power are needed in

Somatotrop adenomas

benign tumors that may grow in an around the brain

can be detected through ___ ____

blood draws

HGH decreases ___ ___

body fat; body fat is 8% and now its 3%-thats not normal or just good nutrition

HGH stimulates the growth of all internal organs excluding the ___

brain

Dwarfism

can be corrected supplementary HGH

GH supplementation ___ ___improve the msucualr strength on non deficient endogenous GH power lifters

does not

GH

growth hormone

Originally intended for the use in children who suffer from ___ disorders and ___ who were not endogenously producing enough GH (dwarfism)

growth; adults

HGH related to intensity?

helps those who are deficient but not really sure about the rest of people

HGH plays a rome in ___

homeostatsis

HGH Increases muscle mass through sarcomere ____ (speed-how fast it can regenerate)

hyperplasia

HGH causes _____ - increased amounts of ___ lead to Increased protein synthesis - GH effects on muscle persist and do not wear off like the effects of anabolic steroids -endogenous levels that are elevated cause ____

hyperplasia; RNA; acromegaly

Anabolic steroids cause ____

hypertrophy; cut bicep across the fibers, exercise, cross-sectional thickness will improve

Why athletes use HGH? 1. increased ___ ___ and streghtens and increases ____ of ____

increased calcium retention; mineralization of bone

HGH promotes

lipolysis

HGH reduces ___ reuptake of glucose

liver

exercise stimulates endogenous HGH output in both ___ and ____

men and women

HGH is the ___ highly sought drug among athletes

most