Meperidine Hydrochloride
Considerations DOA
Category C. caution with asthma copd. narcan should be readily available. onset IM: 10-45 min IV immediate Peak: 30-60 min. last: 2-4 hrs.
Meperidine Hydrochloride
Demerol Opioid analgesic schedule II drug
MOA
Synthetic opioid analgesic whose effects on the central nervous system and smooth muscle organs are similar to morphine, primarily acting as an analgesic and a sedative.
Indications
analgesia for moderate to severe pain
Contraindications
diarrhea caused by poisioning, patients taking maois, during labor or delivery of a premature infant, undiagnosed abdominal pain or head injury.
DI
do not give concurrently with maois. exacerbates cns depression when given with cns depressants.
Side Effects
seizures, confusion, sedation, dysphoria, headache, hallucinations, increased icp, resp depression, apnea, hypotension, bradycardia, dysrhthmias.
Dose/Admin
Adult: 50-10mg IM, SC 25-50mg slowly IV. Pedis: 1-2mg/kg/dose IV, IO, IM, SC