Meperidine Hydrochloride

Considerations DOA

Category C. caution with asthma copd. narcan should be readily available. onset IM: 10-45 min IV immediate Peak: 30-60 min. last: 2-4 hrs.

Meperidine Hydrochloride

Demerol Opioid analgesic schedule II drug

MOA

Synthetic opioid analgesic whose effects on the central nervous system and smooth muscle organs are similar to morphine, primarily acting as an analgesic and a sedative.

Indications

analgesia for moderate to severe pain

Contraindications

diarrhea caused by poisioning, patients taking maois, during labor or delivery of a premature infant, undiagnosed abdominal pain or head injury.

DI

do not give concurrently with maois. exacerbates cns depression when given with cns depressants.

Side Effects

seizures, confusion, sedation, dysphoria, headache, hallucinations, increased icp, resp depression, apnea, hypotension, bradycardia, dysrhthmias.

Dose/Admin

Adult: 50-10mg IM, SC 25-50mg slowly IV. Pedis: 1-2mg/kg/dose IV, IO, IM, SC