PATH 370 - In Class quiz 2 (ch. 10, 11, 13, 14, 15)

which type of leukemia primarily affects children?

ALL (acute lymphoid leukemia)

Treatment for hemophilia A includes

Factor VIII replacement

A patient is diagnosed with CML (chronic myeloid leukemia). The patient may experience which of these symptoms? (select all that apply)

Fatigue weight loss abdominal discomfort sweats

Severe combined immunodeficiency (SCID) syndrome is an example of a(n)

deficient immune response

A laboratory test finding helpful in confirming the diagnosis of iron-deficiency anemia is

elevated total iron-binding capacity

The most effective therapy for anemia associated with kidney failure is

erythropoietin administration

Anemia related to vitamin B12 or folate deficiency is chracterized by what laboratory features? (Select all that apply.)

RBC counts of 500,000 to 750,000 cells/mm3 WBC counts of 4000 to 5000 cells/mm3

A patient is diagnosed with stage III non-Hodgkin lymphoma and is preparing to undergo treatment. Which treatments may be used to treat this patient's cancer? (select all that apply)

Radiation Bone marrow transplant Chemotherapy Monocional antibody therapy

Which diseases may be associated with a bleeding problem? (select all that apply)

Renal failure cirrhosis systemic lupus erythematosus ovarian cancer

One of the cardinal features of sickle cell anemia includes acute and chronic dysfunction of which organs? (select all that apply)

Spleen bones brain lungs

Pernicious anemia is caused by a lack of

intrinsic factor

The cause of the most common form of anemia is

iron deficiency

A primary effector cell of the type I hypersensitivity response is

mast cells

The anemia resulting from a deficiency of either vitamin B12 (cobalamin) or folate is caused by a disruption in DNA synthesis of the blast cells in the bone marrow that produces very large abnormal bone marrow cells called ________

megaloblasts

Thalassemia may be confused with iron deficiency anemia because they are both

microcytic

Renal insufficiency is a common complication of which disease?

myeloma

Hemophilia B is also known as ________ disease

Christmas

anaphylaxis may occur in certain hypersensitivity reactions, including type (select all that apply)

I II

The hypersensitivity reaction that does not involve antibody production is type

IV

A newborn patient is diagnosed with hemolytic disease. The nurse may expect to find what signs and symptoms? (select all that apply)

Petechial hemorrhages hepatomegaly splenomegaly kernicterus

Regarding iron deficiency anemia, what laboratory features are typically decreased? (select all that apply)

MCV MCH MCHC

The Philadelphia chromosome is a balanced chromosome translocation that forms a new gene called

bcr-abl

A cause of thrombocytopenia includes

chemotherapy

A patient is diagnosed with hairy cell leukemia. The patient's lab results would most likely indicate a decrease in (select all that apply)

granulocytes platelets red blood cells

an important mediator of a type I hypersensitivity reaction is

histamine

myasthenia gravis is a type II hypersensitivity disorder that involves

impaired muscle function

The effects of histamine release include

increased vascular permeability

The patient is a 12-year-old boy diagnosed with acute lymphoid leukemia. As part of treatment, the patient must undergo chemotherapy. The most serious complication of chemotherapy is

infection

RhoGam (an Rh antibody) would be appropriate in an Rh-________ woman with an Rh-________ antibody titer carrying an Rh-______fetus.

negative;negative;positive

Which disorder is associated with a type III hypersensitivity mechanism of injury?

systemic lupus erythematosus