Patho Module 9 Pretest

Iron is stored in the tissues in what form? a) All of the above b) Hemosiderin c) Myoglobin d) Ferritin

a) All of the above - Iron is stored in muscles as myoglobin but also is stored as ferritin and hemosiderin in the over and bone marrow

What is a reticulocyte? a) An abnormal red blood cell b) An immature red blood cell c) A spleen cell that destroys erythrocytes d) A kidney cell that secretes erythropoietin

b) An immature red blood cell - A reticulocyte is an immune red blood cell

Which of the following proteins is not a normal component of plasma? a) Immunoglobulins b) Collagen c) Albumin d) Clotting factors

b) Collagen - Collagen is a structural component in the wall of the arteries and veins but is not normally found in the plasma

Which of the following in the most important mineral required for erythropoiesis? a) Calcium b) Iron c) Selenium d) Magnesium

b) Iron - Iron is the most important mineral required for erythropoiesis. Iron is necessary for hemoglobin synthesis

In adults, hematopoiesis occurs in the bone marrow of all of the following bones except the: a) Pelvic bone b) Shaft of the femur c) Ribs d) Vertebrae

b) Shaft of the femur - In adults, hematopoiesis does not occur in the bone marrow of the shaft of the femur. It occurs in the bone marrow of the vertebrae, sternum, ribs, cranium, pelvic bones, and very proximal ends of the humerus and femur

What is a megakaryocyte? a) A large blood cell that participates in blood clotting b) A large phagocytic immune cell in the bone marrow c) A large liver cell that produces bilirubin from hemoglobin d) A large bone marrow cell that breaks apart into platelets

d) A large bone marrow cell that breaks apart into platelets - A megakaryocyte is a large bone marrow cell that breaks apart into platelets

What is a thrombocyte? a) A blood clot in a vein b) An immature blood cell c) A phagocytic cell d) A platelet

d) A platelet - A thrombocyte is a platelet

Which one of the following is a secondary lymphoid organ capable of releasing up to 200 mL of blood into the circulation to restore blood volume in the case of hemorrhage? a) Spleen b) Liver c) Bone marrow d) Pancreas

a) Spleen - The spleen is a secondary lymphoid organ that serves as a blood reservior and also contains macrophages and lymphocytes

Which of the following is a characteristic of mature erythrocytes? a) Are produced in the spleen b) Have a spherical shape c) Have no nucleus d) Contain the protein transferrin

c) Have no nucleus - During the final stages of erythropoiesis, the nucleus is extruded from the developing red blood cell

Red blood cell lysis in the spleen yields which one of the followng? a) Fibrin b) Vitamin B12 c) Hematopoietic growth factor d) Bilirubin

d) Bilirubin - Bilirubin is formed from degraded hemoglobin that gets released after old of injured red blood cells are phagocytized in the spleen

Which one of the following molecules forms a meshwork that stabilizes the platelet plug during hemostasis? a) Collagen b) Fibrinogen c) Thrombin d) Fibrin

d) Fibrin - Fibrin is the insoluble end product of the clotting cascade that forms the meshwork in a blood clot

When plasmin degrades fibrin during the fibrinolytic process, what is (are) the by product(s) called? a) Tissue thromboplastin b) Thrombopoietin c) Clotting factors d) Fibrin degradation products

d) Fibrin degradation products - The degradation of fibrin by plasmin creates fibrin degradation products (FDPs), which also help to dissolve the clot

Erythropoietin is released by the: a) Red blood cells b) Spleen c) Bone marrow d) Kidneys

d) Kidneys - Erythropoietin is released by the kidneys in response to hypoxia

Where in the body are clotting factors synthesized? a) Spleen b) Bone marrow c) Kidneys d) Liver

d) Liver - Clotting factors are proteins synthesized by the liver cells

What is the function of stem cells in the bone marrow? a) They provide the collagen framework in which blood cells reside while maturing b) They destroy blood cells that are developing normally c) They secret antibodies that protect immature blood cells d) They differentiate into the blast cells that differentiate into mature blood cells

d) They differentiate into blast cells that differentiate into mature blood cells - Stem cells differentiate into blast cells that differentiate into mature blood cells