Physiological Psychology - Exam 7
For patients suffering with depression, REM sleep ___________. - composes almost 80% of the sleep period - is nonexistent - begins earlier in the sleep cycle - is decreased by about half
begins earlier in the sleep cycle
The anxiolytics that have the highest abuse and addiction potentials are ___________. - benzodiazepines - barbituates - SNRIs - tricyclics
benzodiazepines
Napolean has been diagnosed with major depression and has jumped from conventional antidepressant to conventional antidepressant over a year and a half with no improvement in symptoms. When he switches to bupropion, an atypical antidepressant, at first he thinks it's working as planned. Most of the time, he feels giddy and quick on his feet, but he gets increasingly irritable, anxious, and sleep-deprived, and he runs up $5,000 on his credit card in two weeks. At his next psychiatrist appointment, his provider says Napolean was originally misdiagnosed. What condition is the provider likely to diagnose? - borderline personality disorder - reactive depression - bipolar disorder - seasonal affective disorder
bipolar disorder
Which of the following disorders is characterized by aggression and hostility to others without a clear motive? - borderline personality disorder - PTSD - generalized anxiety disorder - OCD
borderline personality disorder
In resistant patients, __________ combined with antidepressant medication leads to significant improvement in depression scores. - ketamine - cognitive behavioral therapy - a low-dose antipsychotic - systematic desensitization
cognitive behavioral therapy
If someone with anxiety has problems with controlling their emotions when confronted with anxiety-inducing events or thoughts, they have underactivity in the _____________ network, which also engages in self-monitoring and future planning. - default mode - ventral attention - frontoparietal - salience
default mode
How does the heritability for depression appear to vary by gender? - degree of severity is more heritable in women than men - most meaningful genes for major depression are linked to the Y-chromosome - more heritable when a birth mother has depression - depression is more heritable in women than men
depression is more heritable in women than men
How have suicide rates in the United States changed since the early 2000s? - they are now more often committed by those without psychiatric illness - decreased success rate in adolescents whose parents are mentally ill - dramatically increased number of successful attempts in both men and women - suicide rates fell in young adults after SSRI prescriptions to that age group decreased
dramatically increased number of successful attempts in both men and women
In BPD, a poor environment can create _________ changes to genes that result in impulsivity and inappropriate behaviors. - maladaptive - mutation - epigenetic - compensatory
epigenetic
A portion of the SLC6A4 serotonin transporter gene has been associated with _____________. - a decreased vulnerability to depression - exaggerated amygdala response - 15% decrease in white matter in the amygdala - 2% decrease in the subgenual anterior cortex
exaggerated amygdala response
What effect has been reported to occur in the brains of those with schizophrenia? - failure of migration of cells to the outer cortical layers in the frontal lobe - disorganized neurons found in the deeper gray layers of the brain - problems with factors that encourage cellular migration in the hippocampus - increase in reelin, causing abnormal formation of layers in the temporal lobe
failure of migration of cells to the outer cortical layers in the frontal lobe
Which symptom is most characteristic of post-traumatic stress disorder (PTSD)? - flashbacks - flat effect - sensation-seeking - undersensitivity to environmental stimuli
flashbacks
A person who has a feeling of stress and worry most of the time probably has _______________. - panic disorder - a phobia - OCD - generalized anxiety
generalized anxiety
The National Institute of Mental Health would encourage researchers to focus on which aspect of schizophrenia in a proposed study? - identifying genes strongly associated with schizophrenia - linking specific structural abnormalities in the brain to specific symptoms - validating a scale to distinguish paranoid and catatonic schizophrenia - determining the unique disease processes of each category of schizophrenia
identifying genes strongly associated with schizophrenia
Joe claims that he sees ghosts everywhere. If we put him in an fMRI during one of his experiences and asked him to observe ghosts in the room, what would we see in the fMRI scan? - heightened activity in the prefrontal cortex - decreased activity in the parietal lobes - reduced activity in the temporal lobes - increased activity in the occipital lobes
increased activity in the occipital lobes
Cortical activity of depressed patients most consistently shows ____________. - increased activity in the ventral prefrontal cortex - decreased activity in the dorsal prefrontal cortex - increased activity in the caudate nucleus - decreased activity in the amygdala
increased activity in the ventral prefrontal cortex
Lowered 5-HIAA, which may be a potent biochemical indicator of suicide risk, has what effect on at-risk individuals? - creates over-compensatory spikes and valleys of serotonin - increases impulsivity - rebounds energy levels - results in risky sensation-seeking behaviors
increases impulsivity
Many people with depression smoke because _____________. - the body's stress response to inhaling smoke increases adrenaline - tobacco inhibits GABA production - nicotine increases their serotonin levels - ingredients in tobacco act as monoamine oxidase inhibitors
ingredients in tobacco act as monoamine oxidase inhibitors
Which side effect of traditional antipsychotics was originally taken as a sign that the dosage was at an appropriate level? - agranulocytosis - cardiac arrhythmia - seizures - involuntary muscle movements
involuntary muscle movements
Which of the following drugs produces the most rapid--yet shortest-acting--effect on symptoms of depression? - iproniazid - fluoxetine - monoamine oxidase inhibitors - ketamine
ketamine
Smoking is more frequent among those with schizophrenia than in the nonschizophrenic population, probably because ___________. - nicotine normalizes sensory gating - nicotine helps to improve long-term memory functioning - routines are highly ingrained in people with schizophrenia - people with schizophrenia have difficulty evaluating long-term risk
nicotine normalizes sensory gating
Which of the following areas shows abnormalities in OCD? - occipital lobe - hippocampus - orbitofrontal cortex - pineal gland
orbitofrontal cortex
What differentiates Type I schizophrenia from Type II schizophrenia? - positive symptoms and negative symptoms, respectively - early onset and late onset, respectively - genetically based and environmentally based, respectively - disabling and mild severity, respectively
positive symptoms and negative symptoms, respectively
The MAOI antidepressant isocarboxazid (Marplan) would have what effect on depression? - block the reuptake of serotonin and norepinephrine - stimulate serotonin production at the synapse - metabolize into nicotine to activate nicotinic resceptors - prevent the destruction of excess monoamines at axon terminals
prevent the destruction of excess monoamines at axon terminals
The decrease in coordination and communication between the prefrontal cortex and hippocampus of individuals with schizophrenia is partly due to ___________. - reductions in glia cells - decreases in serotonin productivity - reductions in myelinated axons - decreases in myelinated cell bodies
reductions in myelinated axons
What type of effects differentiate second generation or atypical antipsychotics from traditional antipsychotics? - serotonergic - dopaminergic - glutamate-regulating - GABA-inhibiting
serotonergic
Genes for which neurotransmitter are most implicated in the anxiety disorders? - glutamate - serotonin - dopamine - adenosine
serotonin
Individuals who carry the VAL66MET allele, _____________. - are especially resilient to traumatic stress - are mostly men - show resistance to fear extinction procedures - show a hyperactive connection between the prefrontal cortex and amygdala
show resistance to fear extinction procedures
The ___________ has been suggested as the switch controlling bipolar cycles. - subgenual prefrontal cortex - dorsolateral prefrontal cortex - caudate nucleus - amygdala
subgenual prefrontal cortex
Rob has a significantly low level of 5-HIAA. His therapist should be most concerned about _____________. - suicidal impulses - schizophrenia-related hallucinations - panic attacks - manic behavior
suicidal impulses
In the U.S., what outcome followed a 22% decrease in SSRI prescriptions to adolescents? - total brain activity increased in adolescents - suicide rates of adolescents increased - adolescents suffered accelerated volume reduction in the hippocampus - diagnosis rates for adolescent depression plateaued
suicide rates of adolescents increased
Which is most strongly associated with patients suffering from schizophrenia? - hyperfrontality - autumn birth effect - grandiosity - suicide risk
suicide risk
At the level or neural functioning, ECT ____________. - increases the sensitivity of autoreceptors on dopamine and norepinephrine neurons - decreases GABA concentrations in the brain - synchronizes neuronal firing over large areas of the brain - decreases the sensitivity of serotonin postsynaptic receptors
synchronizes neuronal firing over large areas of the brain
The high concordance rate for affective disorders in identical twins drops only slightly when they are reared apart, suggesting that ___________. - the most important environmental influences have already occurred - environmental influence is very weak throughout the life course - when one twin is diagnosed, the other twin will be diagnosed at some point in their life - the environmental differences are created by the genetic differences
the most important environmental influences have already occurred
The idea that genes may predispose a person toward schizophrenia but the environment contributes as well is called the ___________ model. - continuum - trigger - etiology - vulnerability
vulnerability
In the U.S., the annual economic burden of schizophrenia amounts to ___________. - $165 thousand - $150 trillion - $100 - $156 billion
$156 billion
__________ are more often afflicted with obsessive-compulsive disorder. - Boys - Adults - Children - Girls
Boys
Which of the following is a reported reason as to why adolescence is a particularly significant period in the development of schizophrenia? - Substance use typically begins in this period. - Frontal myelination is occurring during this period. - Hormonal changes occur. - Sexual activity begins during this time, which can increase stress levels.
Frontal myelination is occurring during this period.
Prolonged suffering from PTSD can particularly damage which area of the brain? - Hippocampus - Amygdala - Insular cortex - Anterior cingulate cortex
Hippocampus
What factor impacts the effectiveness of dopamine-blocking drugs in schizophrenia treatment? - They eventually trigger the formation of new D2 receptors. - Tardive dyskinesia decreases the effectiveness of these drugs. - Patients with low levels of receptor blocking may still respond to the drugs. - Some patients with schizophrenia have a dopamine deficiency.
Some patients with schizophrenia have a dopamine deficiency.
Although visual hallucinations are not as common as auditory ones, the visual hallucinations may be due to ____________. - activity in the occipital lobes - lack of local connections in the temporal lobes - lack of local connectivity in the visual cortex - the hypofrontality effect
activity in the occipital lobes
Which of the following areas of the brain shows increased activity in individuals suffering from PTSD? - thalamus - amygdala - hypothalamus - hippocampus
amygdala
Michael is frustrated and pacing his bedroom because he has had the same line of a pop song he hates intruding in his thoughts for three hours now. He is growing increasingly anxious that it won't ever leave his head. What type of behavior is this? - paranoia - a phobia - an obsession - a compulsion
an obsession
Which of the following is least characteristic of schizophrenia? - paranoia - lack of emotion - hallucinations - anxiety
anxiety
Chronic symptoms of schizophrenia ___________. - are likely to develop gradually - are typically more responsive to treatment - often have a good prognosis - are more common in men than women
are likely to develop gradually
The heritability factor in most studies of schizophrenia is ___________. - 5-10% - 60-90% - 25-50% - 90-100%
60-90%
The first antidepressant was _____________, a drug originally developed as a treatment for tuberculosis. - Iproniazid - Amphetamine - Fluoxetine - L-tryptophan
Iproniazid
Larry was diagnosed with OCD. What might his doctor tell him regarding the diagnosis? - It may occur following head injury. - It involves problems in the occipital lobe. - There is most likely an environmental component. - It can have an acute onset in adults after a bacterial infection.
It may occur following head injury.
_______________ disorders include Tourette syndrome, obsessive-compulsive disorder, and borderline personality disorder. - Affective - Psychotic - Stress-related - Personality
Personality
The most effective pharmacological treatment for obsessive-compulsive disorder is/are ____________. - SSRIs - benzodiazepines - lithium - drugs that increase glutamate
SSRIs
Which neurotransmitters are out of balance for individuals suffering from borderline personality disorder? (NOTE- you may have to select more than one answer for full credit.) - Serotonin - Dopamine - Epinephrine - Acetylcholine - GABA - Norepinephrine
Serotonin and Dopamine
Rico hears voices on the radio mocking him for embarrassing himself at dinner with his partner's parents. He checks the radio and sees that it is unplugged, but the people on the radio just keep laughing at him. What is the current understanding of the source of these voices? - His auditory area is oscillating in synchrony with other brain areas, causing him to hear unpredictable noises. - These are his own thoughts, misinterpreted as an outside noise from another person. - External noises are given excessive significance, so they are perceived as voices. - His brain is stuck in a memory loop, recycling criticisms he has heard from others and projecting them outward.
These are his own thoughts, misinterpreted as an outside noise from another person.
