Subject Review

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What form of immunity is expected to provide long-term protection after hepatitis B vaccine is administered to an immunocompetent person?

Active - Active immunity can be acquired by natural exposure in response to an infection or a natural series of infections, or through intentional infect of an antigen.

The serum from a patient of African-American descent is reactive with all screening and panel cells. Which antibody directed to a high incidence antigen is most likely to be present?

Anti-U - The U antigen is located on glycophorin B, a glycoprotein that carries the S,s, and U antigens in the MNS blood group system. Individuals who are U-negative are also S-s- and are black descent. This phenotype is never found in the white population.

Which of the following is the best media for recovery and presumptive identification of Clostridioides difficile in suspected cases of pseudomembraneous colitis?

Cycloserine-cefoxitin fructose agar (CCFA) - used to recover Clostridioides difficle from stool specimens. This media is selective and differential for the recovery and presumptive identification of the organism.

If a pipette is labeled (TC) "to contain" you would do the following

Drain contents then rinse out with diluting fluid - TC means the total volume contained in the pipette. These pipettes are calibrated to contain a specific volume, but are not calibrated to deliver that specific amount.

Examples of cytokines originating from activated T-cells include

IL-2 and IL-3 - IL-2, IL-3 are cytokines previously called T-cell growth factor (IL-2) and Multicolony stimulating factor (IL-3), and are two of the known cytokines that originated from activated T-cells

A gram positive bacillus that has a rod-coccus cycle (short, thin rods in young cultures and cocci in older cultures) and an odor resembling cheese is

Brevibacterium spp. - Brevibacterium has its habitat in milk and milk products, and responsible for both the color (yellow) and aroma of certain cheeses.

Which of the following best describes the benefits of the RPR or VDRL tests

Monitoring course of treatment - The RPR and VDRL detect nontreponemal antibody proteins called reagin that the body produces in response to infection with T. pallidum. Because reagin proteins are also detected in pregnancy, old age, Lupus, and other syndromes and disease states, the RPR and VDRL tests are very sensitive but not highly specific and so a confirmatory test specifically for treponemal organisms or antibodies needs to be performed.

Washing red cells may be performed to remove what from the unit?

Proteins - Washing red cells removes remaining plasma proteins that are present in the unit


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